StaTips Part V: The adjustment of the P value in the context of multiple comparisons

  • Perinetti Giuseppe Private practice, Nocciano (PE)

Abstract


Very often researchers face the problem of multiple comparisons using the same data sets. When performing multiple comparisons,it happens that some P values below the desired cut-off level will be retrieved by chance, thus leading the researcher to havefalse positives. To reduce the risk of making wrong conclusions, statistical adjustment of the P values in the context of multiplecomparisons has been proposed over the last decades. This article will deal with two simple procedures, Bonferroni and Holm,commonly used in dental literature to adjust the P values in case of multiple comparisons.

References

Perinetti G. StaTips Part I: Choosing statistical test when dealing with differences. South Eur J Orthod Dentofac Res. 2016;3:4-5.

Glantz S. Primer of Biostatistics. 7th ed. Columbus: McGraw-Hill Education; 2011.

Holm S. A simple sequentially rejective multiple test procedure. Scand J Statistics. 1979;6:65-70.

Shaffer JP. Multiple hypothesis testing. Ann Rev Psychol. 1995;46:561-84.

Aickin M, Gensler H. Adjusting for multiple testing when reporting research results: the Bonferroni vs. Holm methods. Am J Public Health. 1996;86:726-8.

Published
2018/11/23
Section
Short Communication