Šta je neobično kod asimptomatskih pacijenata? Izolacija A. urinae kod deteta sa fimozom
Ključne reči:
A. urinae, urinarna infekcija, rezistencija, antibiotici
Sažetak
U ovom radu prikazujemo prvi slučaj izolacije Aerococcus urinae iz uzorka urina petogodišnjeg dečaka sa prebivalištem u AP Vojvodini (Srbija). Pacijent je imao predisponirajuće faktore povezane sa osetljivošću genitourinarnog sistema na infekciju. Onim toga, pacijent nije prijavio nijednu pritužbu u vezi sa aktivnim urinarnim infekcijama. Eradikcija A. urinar je postignuta nakon 10-dnevnog lečenja meropenemom.
Iz ovog slučaja nameće se pitanje - da li postoji mogućnost da su infekcije urinarnog trakta sa A. urinae zanemarene kod pedijatrijskih pacijenata sa predisponirajućim faktorima genitourinarnog sistema za infekciju? Tek nakon širokog uvođenja MALDI-TOF MS u nadležne laboratorije, moći ćemo da damo precizan odgovor.
Reference
References:
1. Rasmussen M. Aerococcus : an increasingly acknowledged human pathogen. Clin Microbiol Infect. 2016;22(1):22-27. doi:10.1016/j.cmi.2015.09.026
2. Aguirre M, Collins MD. Phylogenetic analysis of some Aerococcus-like organisms from urinary tract infections: description of Aerococcus urinae sp. nov. J Gen Microbiol. 1992;138(2):401-405. doi:10.1099/00221287-138-2-401
3. Rasmussen M. Aerococci and aerococcal infections. J Infect. 2013;66(6):467-474. doi:10.1016/j.jinf.2012.12.006
4. Forsvall A, Wagenius M, Rasmussen M. Perigenital necrotizing soft tissue infection caused by Aerococcus urinae. IDCases. 2019;18. doi:10.1016/j.idcr.2019.e00590
5. Yabes JM, Perdikis S, Graham DB, Markelz A. A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature. BMC Infect Dis. 2018;18. doi:10.1186/s12879-018-3414-0
6. Varughese R, Mathew A, Chadha R, Kostka J, Regelmann D. Prosthetic valve endocarditis caused by Aerococcus Urinae. IDCases. 2020;21:e00912. doi:10.1016/j.idcr.2020.e00912
7. Murray TS, Muldrew KL, Finkelstein R, Hampton L, Edberg SC, Cappello M. Acute Pyelonephritis Caused by Aerococcus urinae in a 12-Year-Old Boy. Pediatr Infect Dis J. 2008;27(8):760–762. doi:10.1097/INF.0b013e318170af46
8. Skalidis T, Papaparaskevas J, Konstantinou D, Kapolou E, Falagas ME, Legakis N. Aerococcus urinae, a cause of cystitis with malodorous urine in a child: clinical and microbiological challenges. JMM Case Rep. 2017;4(2):e005083. doi:10.1099/jmmcr.0.005083
9. Gibb AP, Sivaraman B. A second case of foul smelling urine in a boy caused by Aerococcus urinae. Pediatr Infect Dis J. 2013;32(11):1300-1301. doi:10.1097/INF.0b013e3182a64054
10. de Vries TW, Brandenburg AH. Foul smelling urine in a 7-year-old boy caused by Aerococcus urinae. Pediatr Infect Dis J. 2012;31(12):1316-1317. doi:10.1097/INF.0b013e318268d25e
11. Lenherr N, Berndt A, Ritz N, Rudin C. Aerococcus urinae: a possible reason for malodorous urine in otherwise healthy children. Eur J Pediatr. 2014;173(8):1115-1117. doi:10.1007/s00431-014-2348-9
12. Sierra-Hoffman M, Watkins K, Jinadatha C, Fader R, Carpenter JL. Clinical significance of Aerococcus urinae: a retrospective review. Diagn Microbiol Infect Dis. 2005;53(4):289-292. doi:10.1016/j.diagmicrobio.2005.06.021
1. Rasmussen M. Aerococcus : an increasingly acknowledged human pathogen. Clin Microbiol Infect. 2016;22(1):22-27. doi:10.1016/j.cmi.2015.09.026
2. Aguirre M, Collins MD. Phylogenetic analysis of some Aerococcus-like organisms from urinary tract infections: description of Aerococcus urinae sp. nov. J Gen Microbiol. 1992;138(2):401-405. doi:10.1099/00221287-138-2-401
3. Rasmussen M. Aerococci and aerococcal infections. J Infect. 2013;66(6):467-474. doi:10.1016/j.jinf.2012.12.006
4. Forsvall A, Wagenius M, Rasmussen M. Perigenital necrotizing soft tissue infection caused by Aerococcus urinae. IDCases. 2019;18. doi:10.1016/j.idcr.2019.e00590
5. Yabes JM, Perdikis S, Graham DB, Markelz A. A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature. BMC Infect Dis. 2018;18. doi:10.1186/s12879-018-3414-0
6. Varughese R, Mathew A, Chadha R, Kostka J, Regelmann D. Prosthetic valve endocarditis caused by Aerococcus Urinae. IDCases. 2020;21:e00912. doi:10.1016/j.idcr.2020.e00912
7. Murray TS, Muldrew KL, Finkelstein R, Hampton L, Edberg SC, Cappello M. Acute Pyelonephritis Caused by Aerococcus urinae in a 12-Year-Old Boy. Pediatr Infect Dis J. 2008;27(8):760–762. doi:10.1097/INF.0b013e318170af46
8. Skalidis T, Papaparaskevas J, Konstantinou D, Kapolou E, Falagas ME, Legakis N. Aerococcus urinae, a cause of cystitis with malodorous urine in a child: clinical and microbiological challenges. JMM Case Rep. 2017;4(2):e005083. doi:10.1099/jmmcr.0.005083
9. Gibb AP, Sivaraman B. A second case of foul smelling urine in a boy caused by Aerococcus urinae. Pediatr Infect Dis J. 2013;32(11):1300-1301. doi:10.1097/INF.0b013e3182a64054
10. de Vries TW, Brandenburg AH. Foul smelling urine in a 7-year-old boy caused by Aerococcus urinae. Pediatr Infect Dis J. 2012;31(12):1316-1317. doi:10.1097/INF.0b013e318268d25e
11. Lenherr N, Berndt A, Ritz N, Rudin C. Aerococcus urinae: a possible reason for malodorous urine in otherwise healthy children. Eur J Pediatr. 2014;173(8):1115-1117. doi:10.1007/s00431-014-2348-9
12. Sierra-Hoffman M, Watkins K, Jinadatha C, Fader R, Carpenter JL. Clinical significance of Aerococcus urinae: a retrospective review. Diagn Microbiol Infect Dis. 2005;53(4):289-292. doi:10.1016/j.diagmicrobio.2005.06.021
Objavljeno
2025/12/22
Broj časopisa
Rubrika
Prikaz slučaja / Case report