Uticaj flaširane Prolom vode na litogenezu urinarnog trakta

  • prof. dr Dragoslav Bašić prof. Dragoslav Bašić (e-mail: basicdr@gmail.com).
Ključne reči: Flaširana Prolom voda, litogeneza, urinarni trakt

Sažetak


Urolitijaza predstavlja najčešće urološko oboljenje danas, sa rastućim trendom incidencije i prevalencije, u zavisnosti od geografskih, klimatskih, etničkih, dijetalnih i genetskih faktora. Profilaktičko lečenje urolitijaze u smislu visokog unosa tečnosti od velikog je značaja u prevenciji svih vrsta urolitijaze. Flaširana Prolom voda kategorisana je kao natrijum hidrokarbonatna alkalna hipotermalna oligomineralna voda. Cilj studije bio je da se ispitaju efekti unosa Prolom vode na serumske i urinarne vrednosti kalcijuma i magnezijuma, kao i na pH urina i bubrežnu mikrolitijazu. Multicentričnom prospektivnom studijom uključeno je ukupno 345 pacijenata koji su tokom 14 dana oralno unosili flaširanu prolom vodu u količini od 2,5 do 3 litra dnevno, uz praćenje u tri perioda. Prosečne vrednosti kalcijuma u serumu (mmol / l) nultog, 7. i 14. dana bile su: 2,24; 2,312 i 2,242, ponaosob. Prosečne vrednosti kalcijuma u urinu (mmol / l) nultog, 7. i 14. dana bile su: 1.046; 1,582 i 1,564, ponaosob. Prosečne vrednosti magnezijuma u serumu (mmol / l) nultog, 7. i 14. dana bile su: 0,89; 0,82 i 0,81, ponaosob. Prosečne vrednosti magnezijuma u urinu (mmol / l) nultog, 7. i 14. dana bile su: 1,09; 1,51 i 1,61, ponaosob. Srednje vrednosti pH u urinu bile su: 6,3 nultog; 5,9 sedmog i 6,8 četrnaestog dana. Svakodnevni unos 2,5-3 litra flaširane Prolom vode ima povoljan i antitilitogeni uticaj na kalcijum-oksalatnu i kalcijum-fosfatnu urolitijazu.

Reference

Alelign T, Petros B. Kidney Stone Disease: An Update on Current Concepts. Adv Urol. 2018 Feb 4;2018:3068365. [CrossRef] [PubMed]

Basavaraj DR, Biyani CS, Browning AJ, J. J. Cartledge JJ. The role of urinary kidney stone inhibitors and promoters in the pathogenesis of calcium containing renal stones. EAU-EBU Update Series 2007(5);3:126-136. [CrossRef]

Borghi L, Meschi T, Amato F, Briganti A, Novarini A, Giannini A. Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomi-zed prospective study. J Urol 1996;155:839. [CrossRef] [PubMed]

Borghi L, Meschi T, Amato F, Briganti A, Novarini A, Giannini A. Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomi-zed prospective study. J Urol 1996;155(3):839-43. [CrossRef] [PubMed]

Brikowski TH, Lotan Y, Pearle MS. Climate-related increase in the prevalence of urolithiasis in the United States. Proc Natl Acad Sci U S A 2008;105:9841-6. [CrossRef] [PubMed]

Chen YK, Lin HC, Chen CS, Yeh SD. Seasonal varia-tions in urinary calculi attacks and their association with climate: a population based study. J Urol 2008; 179:564-9. [CrossRef] [PubMed]

Curhan GC, Willett WC, Rimm EB, Stampfer MJ. A prospective study of dietary calcium and other nutri-ents and the risk of symptomatic kidney stones. N Engl J Med 1993;328:833-8. [CrossRef] [PubMed]

Hesse A, Brändle E, Wilbert D, Köhrmann KU, Alken P. Study on the prevalence and incidence of urolithiasis in Germany comparing the years 1979 vs. 2000. Eur Urol 2003;44:709. [CrossRef] [PubMed]

Knoll T. Epidemiology, Pathogenesis, and Pathophysio-logy of Urolithiasis. European urology supplements 2010;9:802-806. [CrossRef]

Kompletna fizičko hemijska analiza oligomineralne vode “Prolom“- Banja Prolom. Uzorak: Originalna flaša 1,5 l. Institut za rehabilitaciju. Služba za balneo-klimatologiju. Beograd, Sokobanjska 17. Datum 07.02.2004.

Milović N, Elaković D, Aleksić P. Influences of Prolom water on crystalizatiom factor concentration and inhi-bitors of crystaliyation with patients with urolithiasis. 4th Mediterranean Congress of Urology; 1995; Rhodes, Greece.

Pak CY. Kidney stones. Lancet 1998;351:1797-801 [CrossRef] [PubMed]

Pearle MS, Lotan Y. Urinary Lithiasis: Etiology, Epidemiology, and Pathogenesis. Pathogenesis of upper urinary tract calculi. Table 45-2: Diagnostic Classification of Nephrolithiasis. In: Campbell-Walsh Urology, Tenth Edition, Vol I, Wein AJ, editor in chief; Elsevier Saunders, Philadelphia; 2012. p. 1268-9.

Pearle MS, Lotan Y. Urinary Lithiasis: Etiology, Epidemiology, and Pathogenesis. Physicochemistry: 1260-6. In: Campbell-Walsh Urology, Tenth Edition, Vol I, Wein AJ, editor in chief; Elsevier Saunders, Philadelphia 2012. [CrossRef]

Phillips SJ, Whisnant JP. Hypertension and stroke. In: Laragh JH, Brenner BM, editors. Hypertension: patho-physiology, diagnosis, and management. 2nd ed. New York: Raven Press; 1995. p. 465-78.

Sarica K, Inal Y, Erturhan S, Yağci F. The effect of calcium channel blockers on stone regrowth and recurrence after shock wave lithotripsy. Urol Res 2006;34:184. [CrossRef] [PubMed]

Sigurjonsdottir VK, Runolfsdottir HL, Indridason OS, Palsson R, Edvardsson VO. Impact of nephrolithiasis on kidney function. BMC Nephrology 2015;16(1):149. [CrossRef] [PubMed]

Stamatelou KK, Francis ME, Jones CA, Nyberg LM, Curhan GC. Time trends in reported prevalence of kidney stones in the United States:1976-1994. Kidney Int 2003;63:1817. [CrossRef] [PubMed]

Strauss AL, Coe FL, Deutsch L, Parks JH. Factors that predict relapse of calcium nephrolithiasis during treat-ment: a prospective study. Am J Med 1982;72:17-24. [CrossRef] [PubMed]

Taylor EN, Stampfer MJ, Curhan GC. Obesity, weight gain and the risk of kidney stones. Journal of the American Medical Association 2005;293(4):455-62. [CrossRef] [PubMed]

Trinchieri A, Curhan G, Karlsen S, Wu KJ. Epide-miology. In: Segura J, Conort P, Khoury S, editors. Stone Disease. Distributed by Editions 21. Paris, France: ICUD; 2003.

Trinchieri A, Ostini F, Nespoli R, Rovera F, Zanetti G. A prospective study of recurrence rate and risk factors for recurrence after a first renal stone. J Urol 1999; 162:27-30. [CrossRef] [PubMed]

Turk C, Neisius A, Petric A, Seitz C, Scolarikos A, Thomas K. Prevalence, aetiology, risk of recurrence. In: EAU Guidelines of urolithiasis (European Associa-tion of Urology 2019, ed; Urolithiasis – limited update March 2019; EAU Guidelines Office, Arnhem, The Netherlands);8-9. https://uroweb.org/guideline/urolithiasis/ [CrossRef] [PubMed]

Umekawa T, Iguchi M, Kurita T. The effect of osteopontin immobilized collagen granules in the seed crystal method. Urol Res. 2001;29(4):282-6. [CrossRef] [PubMed]

Worcester EM, Coe FL. Nephrolithiasis. Primary Care 2008;35(2):369-91. [CrossRef] [PubMed]

Objavljeno
2020/12/29
Rubrika
Originalni rad