EFIKASNOST LAKA SA FLUOROM U PREVENCIJI DEMINERALIZACIJE GLEĐI
Sažetak
Abstract
Demineralization is a process in which the inorganic content of the enamel structure is lost leading to occurrence of white spot lesions.
The purpose of this study was to examine fluoride varnish effect on enamel.
Material and methods
The study involved 20 premolars extracted for orthodontic reasons. Before the extractions brackets were bonded with one type of adhesive according to manufacturers ‘bonding instructions. After bracket bonding, ten left premolars (test group) were kept dried by careful tooth isolation and the enamel received a topical application of a fluoride varnish (Duraphat®, Germany). Ten right premolars (control group) did not receive any varnish application and brackets were fixed using identical procedures.
After two months, the premolars were extracted and prepared for SEM analysis.
Results
Samples treated with fluoride varnish showed a nearly smooth surface, with complete obtrusion of inter-rod spaces in some fields. The rods appeared as they were fused together with some globules deposited on the surface, relatively no evidence of porosities or irregularities. Within control group demineralization started on enamel surface, but still with adequate and genuine prisms together within interprismatic space. Micro-morphological surface observation of the enamel surfaces showed demineralised surface as rough and uneven tooth enamel (shrinking of prisms, due to the widening of the prismatic spaces).
Conclusion
Fluoride varnish application on enamel surface prevents demineralisation processes.
Fluoride application could act as a ‘barrier’ against the demineralization processes on enamel.
Keywords fluoride varnish, demineralization
Reference
Alessandri Bonetti G, Pazzi E, Zanarini M, Marchionni S, Checchi L. The effect of zinc-carbonate hydroxy-apatite versus fluoride on enamel surfaces after inter-proximal reduction. Scanning 2014;36(3):356-361. [CrossRef] [PubMed]
Ali Abou Neel E, Anas A, Strange A, Salwa I, Melanie C, Young AM, et al. Demineralization–remineralization dynamics in teeth and bone. Int J Nanomedicine 2016;11:4743-63. [CrossRef] [PubMed]
Bruun C, Givskov H. Formation of CaF2 on sound enamel and in caries-like enamel lesions after different forms of fluoride applications in vitro. Caries Res 1991;25:96-100. [CrossRef] [PubMed]
Castillo JL, Milgrom P, Kharasch E, Izutsu K, Fey M. Evaluation of fluoride release from commercially avail-able fluoride varnishes. J Am Dent Assoc 2001;132: 1389-92. [CrossRef] [PubMed]
Cury JA, Tenuta LMA. Enamel remineralization: con-trolling the caries disease or treating early caries lesions? Braz Oral Res 2009;23:23-30. [CrossRef] [PubMed]
Elkassas D, Arafa A. Remineralizing efficacy of dif-ferent calcium-phosphate and fluoride-based delivery vehicles on artificial caries like enamel lesions. J Dent 2014;42(4):466-74. [CrossRef] [PubMed]
He T, Li X, Dong Y, Zhong Y, Yin W, Hu D. Com-parative assessment of fluoride varnish and fluoride film for remineralization of postorthodontic white spot lesions in adolescents and adults over a 6-month period: A single-center, randomized controlled clinical trial. Am J Orthod Dentofacial Orthop 2016;149(6): 810-9. [CrossRef] [PubMed]
Hedman J, Sjöman R, Sjöström I, Twetman S. Fluoride concentration in saliva after consumption of a dinner meal prepared with fluoridated salt. Caries Res 2006;40:158-62. [CrossRef] [PubMed]
Lussi A, Hellwig E, Klimek J. Fluorides-mode of action and recommendations for use. Schweiz Monatsschr Zahnmed 2012;122:1030-6.
Madan N, Madan N, Sharma V, Pardal D, Madan N. Tooth remineralization using bio-active glass - A novel approach. J Academy Adv Dental Research 2011;2: 45-50. [CrossRef]
Paganelli C, Zanarini M, Pazzi E, Marchionni S, Visconti L, Giulio AB. Interproximal enamel reduction: an in vivo study. Scanning 2015;37(1):73-81. [CrossRef] [PubMed]
Peng Y, Qian Z, Ting Z, Jie F, Xiaomei X, Li M. The effect of resin infiltration vs. fluoride varnish in enhancing enamel surface conditions after inter-proximal reduction. Dent Mater J 2016;35:756-61. [CrossRef] [PubMed]
Perrini F, Lombardo L, Arreghini A, Medori S, Siciliani G. Caries prevention during orthodontic treatment: In-vivo assessment of high-fluoride varnish to prevent white spot lesions. Am J Orthod Dentofacial Orthop 2016;149(2):238-43. [CrossRef] [PubMed]
Petzold M. The influence of different fluoride com-pounds and treatment conditions on dental enamel: A descriptive in vitro study of the CaF2 precipitation and microstructure. Caries Res 2001;35(1):45-51. [CrossRef] [PubMed]
Pfarrer AM, Karlinsey RL. Challenges of implementing new remineralization technologies. Adv Dent Res (serial online) 2009 “cited 2015 Dec 15”; Available from: http://adr.sagepub.com/cgi/doi/10.1177/0895937409335643. [CrossRef] [PubMed]
Prabhakar AR, Arali V. Comparison of the remine-ralizing effects of sodium fluoride and bioactive glass using bioerodible gel systems. J Dent Res Dent Clin Dent Prospects 2009;3:117-21. [PubMed]
Retief DH, Sorvas PG, Bradley EL, Taylor RE, Walker AR. In vitro fluoride uptake, distribution and retention by human enamel after 1- and 24-hour application of various topical fluoride agents. J Dent Res 1980;59: 573-582. [CrossRef] [PubMed]
Ritwik P, Aubel JD, Xu X, Fan Y, Hagan J. Evaluation of short-term fluoride release from fluoride varnishes. J Clin Pediatr Dent 2012;36:275-8. [CrossRef] [PubMed]
Roberts MW, Hempton TJ. The Dynamic Process of Demineralization and Remineralization. Dimensions of Dental Hygiene 2009;7(7):16-21.
Shen C, AutiGold J. Assessing fluoride concentration uniformity and fluoride release from three varnishes. J Am Dent Assoc 2002;133:176-82. [CrossRef][PubMed]
Tenuta LM, Cerezetti RV, Del Bel Cury AA, Tabchoury CP, Cury JA. Fluoride release from CaF2 and enamel demineralization. J Dent Res 2008;87:1032-36. [CrossRef] [PubMed]
Weir MD, Chow LC, Xu HHK. Remineralization of demineralized enamel via calcium phosphate nano-composite. J Dent Res. 2012;91(10):979-84. [CrossRef] [PubMed]
Zhang Q, Zou J, Ran Y, Zhou X. Remineralization effects of casein phosphopeptide-amorphous on arti-ficial early enamel lesions of primary teeth. Int J Paediatr Dent 2011;21:374-81. [CrossRef] [PubMed]