GENERALIZOVANA PREOSETLJIVOST NA BOL KOD OBOLELIH OD FIBROMIJALGIJE
Sažetak
Hronični široko rasprostranjeni bol je jedan od glavnih karakteristika fibromijalgije. Kod ovih pacijenata često se uočavaju znaci generalizovane hiperalgezije. Međutim, nije jasno da li je prisutna povećana osetljivost na bol za različite bolne stimuluse. Stoga, cilj ove studije bio je da se ustanovi da li postoje razlike u pragu bola za pritisak (engl. pressure pain threshold – PPT), pragu bola za toplo (engl. Heat pain threshold – HPT) i pragu bola za hladno (engl. Cold pain threshold – CPT) između pacijenata sa fibromijalgijom i zdravih ispitanika. Ova studija preseka uključila je 45 ispitanika (prosečne starosti 54.60 ± 7.96 godina, 88,9% žena), od kojih 23 (51.1%) boluje od fibromijalgije, dok su 22 (48%) bili kontrolna grupa zdravih ispitanika kod kojih PPT, HPT i CPT mereni na podlaktici i na paraspinalnoj muskulaturi lumbosakralne regije kičmenog stuba. Pacijenti oboleli od fibromijalgije imaju značajno niži prag bola na pritisak u poređenju sa grupom zdravih ispitanika: 26.13N/cm2 naspram 53.54N/cm2, (Z=-4.439, p<0.001); HPT 39.70 °C naspram 44.85 °C, (Z=-3.871, p<0.001); CPT 20.51 °C naspram 12.51 °C, (Z=-2.612, p=0.009). U regiji paraspinalne musculature PPT je bio 37.01 N/cm2 naspram 75.77 N/cm2, (Z=-4.178, p<0.001); HPT - 38.18°C naspram 44.13°C (Z=-3.758, p<0.001); CPT - 21.52°C naspram 11.16°C (Z=-2.737, p=0.006). Kod pacijenata obolelih od fibromijalgije prisutna je generalizovana hiperalgezija za sve testirane modalitete (pritisak, toplotu i hladnoću).
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