KARAKTERISTIKE TUMORSKIH PROMENA JAJNIKA U DEČJEM UZRASTU
Sažetak
U proseku, trećina svih adneksalnih masa kod devojčica vodi poreklo od jajnika. Klinička prezentacija je nespecifična. Trend lečenja predstavlja hirurgija čiji je cilj očuvanje jajnika.
Cilj rada jeste prikazati karakteristike tumorskih promena jajnika u populaciji devojčica uzrasta do 18 godina.
Ova retrospektivna studija sprovedena je analizom medicinske dokumentacije ženske novorođenčadi i devojčica uzrasta do 18 godina.
U neonatalnoj grupi, uzrasta do 12 meseci, bilo je 44,4% desnostranih i 55,6% levostranih promena. Kod šest beba (66,7%) urađena je cistektomija, dok je ovariektomija i salpingo-ooferoktimija urađena kod po jedne (11,1%) bebe. U grupi devojčica od jedne godine do 18 godina bilo je 63% desnostranih i 34% levostranih promena. Jedna devojčica imala je obostranu promenu. Kod najvećeg broja devojčica urađena je cistektomija ‒ 24 (63,2%). Od neneoplastičnih promena bilo je devet (23,6%) Cystis follicularis, osam (21,1%) Cystis simplex i šest (17,1%) Corpus luteum haemorrhagicum et cysticum; od neoplastičnih benignih promena bilo je jedanaest (28,8%) Teratoma maturum i četiri (11,4%) Cystadenoma serosum.
Incidencija tumorskih promena jajnika u populaciji devojčica do 18 godina vrlo je niska; znatno češće se javljaju neneoplastične promene.
Reference
Bower R, Dehner LP, Ternberg JL. Bilateral ovarian cysts in the newborn: A triad of neonatal abdominal masses, polyhydramnios, and material diabetes mellitus. Am JDis Child 1974;128:731–733. DOI: https://doi.org/10.1001/archpedi.1974.02110300141022. PMID: 4609177.
Brandt ML, Luks FI, Filiatrault D, Garel L, Desjardins JG, Youssef S. Surgical indications in antenatally diagnosed ovarian cysts. J PediatrSurg 1991;26:276–281. DOI: https://doi.org/10.1016/0022-3468(91)90502-k. PMID: 1827651.
Brown MF, Hebra A, McGeehinK, Ross AJ. Ovarian masses in children: A review of 91 cases of malignant and benign masses. Journal of Pediatric Surgery 1993;28(7):930–932. DOI: https://doi.org/10.1016/0022-3468(93)90700-u. PMID: 8229571.
Cass. DL, Hawkins E, Brand M, Chintagumpala M, Bloss R, Milewicz A. et al. Surgery for Ovarian Masses in Infants, Children, and Adolescents: 102 Consecutive Patients Treated in a 15-year period. Journal of Pediatric Surgery 2013;38(5):693-699.DOI: https://doi.org/10.1053/jpsu.2001.22939. PMID: 11329568.
Depoers C, Lebaccon FA, NyangohTimoh K, MorcetJ, ProisyM, Henno, S, et al. A pre-operative scoring system for adnexal mass in children and adolescents to preserve their future fertility. Journal of Pediatric and Adolescent Gynecology 2019;32(1):57-63.DOI: https://doi.org/10.1016/j.jpag.2018.08.009. PMID: 30205159.
Diamond MP, Baxter JW, Peerman CG Jr, Burnett LS. Occurrence of ovarian malignancy in childhood and adolescence: a community-wide evaluation. ObstetGynecol 1988;71(6 Pt 1):858–860.PMID: 3368170.
Diguisto C, Winer N, Benoist G, Laurichesse-Delmas H, Potin J, Binet A, Lardy H, Morel B, Perrotin F. In-utero aspiration vs expectant management of anechoic fetal ovarian cysts: Open randomized controlled trial. Ultrasound Obstet. Gynecol 2018;52:159–164. DOI: https://doi.org/10.1002/uog.18973. PMID: 29205608.
Hara T, Mimura K, Endo M, Fujii M, Matsuyama T, Yagi K, et al. Diagnosis, Management, and Therapy of Fetal Ovarian Cysts Detected by Prenatal Ultrasonography: A Report of 36 Cases and Literature Review. Diagnostics (Basel) 2021;11(12):2224. DOI: https://doi.org/10.3390%2Fdiagnostics11122224. PMID: 34943461; PMCID: PMC8700714.
HeoSH, Kim JW, Shin SS, Jeong SI, Lim HS, Choi YD et al. Review of Ovarian Tumors in Children and Adoelsecents: Radiologic – Pathologic Correlation. RadioGraphics 2014;34:2039-2055.DOI: https://doi.org/10.1148/rg.347130144. PMID: 25384300.
Kirkham YA, Lacy JA, Kives S, Allen L. Characteristics and management of adnexal masses in acanadian pediatric and adolescent population. J ObstetGynaecol Can 2011;33(9):935–943.
Kives S, Gascon S, Dubuc E, Van Eyk N. No. 341-diagnosis and management of adnexal torsion inchildren, adolescents, and adults
Lecarpentier E, Dreux S, Blanc T, Schaub B, Ville Y, Mandelbrot L, Ghoneimi AE, Oury J, Muller F. Biochemical analysis of cystic fluid in the diagnosis of fetal intra-abdominal masses. PrenatDiagn2012;32:627–632. DOI: https://doi.org/10.3390%2Fdiagnostics11122224. PMID: 34943461; PMCID: PMC9700714.
Liu H, Wang X, Lu D, Liu Z et Shi G. Ovarian masses in children and adolescent in China: analysis of 203 cases. J Ovarian Res 2013;6:47.DOI: https://doi.org/10.1186%2F1757-2215-6-47. PMCID: PMC3729529; PMID: 23826706
Luczak J, Baglaj M, Dryjanski P, Kalcowska A, Banaszyk-Pucala N, Boczar M, et al. What Should Be the Topics of a Prospective Study on Ovarian Masses in Children?-Results of a Multicenter Retrospective Study and a Scoping Literature Review. CurrOncol2022;29(3):1488-1500. DOI:https://doi.org/10.1016/j.jpedsurg.2018.08.058. PMID: 35323325; PMCID: PMC8946882.
Luthra M, Kumar C. Surgical Management of Adnexal Masses in the Pediatric and Adolescent Age Group: Our Experience. J Indian AssocPediatrSurg2021;26(5):287-293. DOI:https://doi.org/10.4103%2Fjiaps.JIAPS_136_20. PMID:34728912; PMCID: PMC8515539.
Merino MJ, Jaffe G. Age contrast in ovarian pathology. Cancer 1993;71(2):537–544.DOI: https://doi.org/10.1002/cncr.2820710208. PMID: 8420674.
Monnery-Noche ME, Auber F, JounnicJM, BeniflaJL, Carbonne B, Dommergues M et al. Fetal and neonatal ovarian cyst: is surgery indicated?.PrenatDiagn 2008;28:15-30. DOI: https://doi.org/10.1002/pd.1915. PMID: 18186135.
Peters H, Himelstein-Braw R, Faber M. The normal development of the ovary in childhood. ActaEndocrinol 1976;82:617-630. DOI: https://doi.org/10.1530/acta.0.0820617. PMID: 947131.
Rogers E, Casadiego CG, Lacy J, Gerstle JT, Kives S, Allen L. Preoperative Risk Stratification of Adnexal Masses: Can We Predict the Optimal Surgical Management?, Journal of Pediatric and Adolescent Gynecology 2014;27(3):125-128.DOI: https://doi.org/10.1016/j.jpag.2013.09.003. PMID: 24560684.
Sadeghian N, Sadeghian I, Mirshemirani A, KhaleghnejadTabari A, Ghoroubi J, AbdollahGorji F, Roushanzamir F. Types and frequency of ovarian masses in children over a 10-year period. Caspian J Intern Med2015;6(4):220-223. PMID: 26644896; PMCID: PMC4649271.
Schultz KA, Sencer SF, Messinger Y, Neglia JP, Steiner ME. Pediatric ovarian tumors: a review of 67 cases. Pediatr Blood Cancer 2005;44(2):167–173.DOI: https://doi.org/10.1002/pbc.20233. PMID: 15490488.
Shah RU, Lawrence C, Fickenscher KA, Shao L, Lowe LH. Imaging of pediatric pelvic neoplasms. RadiolClin North Am 2011;49(4):729–748.DOI: https://doi.org/10.1016/j.rcl.2011.05.007. PMID: 21807171.
Skinner MA, Schlatter MG, Heifetz SA, Grosfeld JL. Ovarian neoplasms in children. Arch Surg 1993;128(8):849–853.DOI: https://doi.org/10.1001/archsurg.1993.01420200023004. PMID: 8343057
Sri Paran T, Mortell A, Devaney D, et al: Mucinous cystadenoma of the ovary in perimenarchal girls. PediatrSurgInt 2006;22:224. DOI: https://doi.org/10.1007/s00383-005-1624-1. PMID: 16416281.
Takayasu H, Masumoto K, Tanak N, Aiozoshi T, Sasaki T, Ono K, Chiba F. et al. A Clinical review of ovarian tumors in children and adolescents.PediatrSurgInt 2020;36(6):701-709.DOI: https://doi.org/10.1007/s00383-020-04660-w. PMID: 32346848.
Tyraskis A, Bakalis S, David AL, Eaton S, Coppi PD. A systematic review and meta-analysis on fetal ovarian cysts: Impact of size, appearance and prenatal aspiration. Prenat Diagn 2017;37:951–958. DOI: https://doi.org/10.1002/pd.5143. PMID: 28886226.
Xac MC, JetelinaKK, JarinJ,WilsonE. Benign, Borderline, and Malignant Pediatric Adnexal Masses: A 10-Year Review. Journal of Pediatric and Adolescent Gynecology 2021;34(4):454–461. DOI:https://doi.org/10.1016/j.jpag.2021.01.002. PMID: 33453397.
Zhang M, JiangW, Li G, Xu C . Ovarian Masses in Children and Adolescents - An Analysis of 521 Clinical Cases. Journal of Pediatric and Adolescent Gynecology 2014;27(3):e73–e77. DOI: https://doi.org/10.1016/j.jpag.2013.07.007. PMID: 24157281.