POJAVA RAZLIČITIH VRSTA DEPRESIJE KOD PACIJENTKINJA SA KARCINOMOM GRLIĆA MATERICE
Sažetak
Informacija da osoba boluje od teške bolesti koja je opasna po život, iznenadnа hospitalizacijа, hirurškа intervencijа i drugе mogućnosti lečenja koje mogu ugroziti biopsihosocijalni integritet pojedinca predstavljaju stresnu situaciju koja može dovesti do akutne reakcije na stres ili poremećaja prilagođavanja.
Globalni cilj ovog istraživanja bio je da se ispita uticaj vrste terapije karcinoma grlića materice na psihički status pacijentkinja i pojavu depresije.
Osnovni princip istraživanja bila je komparativna analiza rezultata dobijenih korišćenjem instrumenata za procenu stepena depresije u eksperimentalnoj i kontrolnoj grupi. U okviru prve eksperimentalne grupe izvršeno je poređenje pacijentkinja koje su podvrgnute operaciji i postoperativnoj hemoradijaciji. U okviru druge eksperimentalne grupe urađeno je poređenje pacijentkinja koje nisu bile operisane, ali su bile podvrgnute radikalnoj hemoradijaciji. Korišćeni su sledeći instrumenti istraživanja: polustrukturirani psihijatrijski intervju, ginekološki parametri (lokalni nalazi i stadijum bolesti) i Hamiltonova skala za depresiju.
Univarijantna logistička regresiona analiza pokazala je da je kod pacijentkinja pre operacije (OR = 24,17; 95% PI: 4,81–121,57 i p < 0,001) i kod pacijentkinja pre radikalne hemoradijacije (OR = 45,99; 95% PI: 8,70–243,15 i p < 0,001) postojao značajno veći rizik od razvoja depresije nego kod pacijentkinja iz kontrolne grupe.
Radikalna histerektomija je praćena porastom depresivnosti i u preoperativnom periodu i nakon operativnog lečenja. Radikalna hemoradijacija dovodi do povećanja depresivnosti u većem stepenu nego radikalna histerektomija i pre i posle tretmana.
Reference
Alipour A, Pour Y. Effect of cognitive behavioral therapy in hastening recovery of women after hysterectomy surgery. J Behav Sci 2010;4(2):91–5.
Awadalla AW, Ohaeri JU, Gholoum A, Khalid AO, Hamad HM, Jacob A. Factors associated with quality of life of outpatients with breast cancer and gynecologic cancers and their family caregivers: a controlled study. BMC Cancer 2007;7:102. [CrossRef][PubMed]
Azizi A, Achak D, Boutib A, Chergaoui S, Saad E, Hilali A, et al. Association between cervical cancer-related anxiety and depression symptoms and health-related quality of life: A Moroccan cross-sectional study. Clinical Epidemiology and Global Health 2023;22:101328. [CrossRef]
Bahri N, Tohidinik HR, Fathi Najafi T, Larki M, Amini T, Askari Sartavosi Z. Depression Following Hysterectomy and the Influencing Factors. Iran Red Crescent Med J 2016;18(1):e30493. [CrossRef][PubMed]
Carlson LE, Bultz BD. Benefits of psychosocial oncology care: improved quality of life and medical cost offset. Health Qual Life Outcome 2003;1:8. [CrossRef][PubMed]
Choi HG, Rhim CC, Yoon JY, Lee SW. Association between hysterectomy and depression: a longitudinal follow-up study using a national sample cohort. Menopause 2020;27(5):543-9. [CrossRef][PubMed]
Conic I, Miljkovic S, Tosic-Golubovic S, Stanojevic Z, Milenkovic D, Djordjevic B, et al. Anxiety levels related to the type of therapy for cervical cancer. Cent Eur J Med 2012;7:490-6. [CrossRef]
Conic I, Stanojevic Z, Dedovic I, Lilic G. Anxiety and depression in patients suffering from cervical cancer estimated before surgery. Acta Medica Medianae 2008;47:49-53.
Dhakal K, Chen C, Wang P, Faustine Mboineki J, Adhikari B. Existing psychological supportive care interventions for cervical cancer patients: a systematic review and meta-analysis. BMC Public Health 2024;24(1):1419. [CrossRef][PubMed]
Distefano M, Riccardi S, Capelli G, Costantini B, Petrillo M, Ricci C, et al. Quality of life and psychological distress in locally advanced cervical cancer patients administered pre-operative chemoradiotherapy. Gynecol Oncol 2008;7:25-9. [CrossRef][PubMed]
Filho AM, Laversanne M, Ferlay J, Colombet M, Pineros M, Znaor A, et al. The GLOBOCAN 2022 cancer estimates: Data sources, methods, and a snapshot of the cancer burden worldwide. Int J Cancer 2024;156(7):1336-46. [CrossRef][PubMed]
Kain ZN, Sevarino F, Alexander GM, Pincus S, Mayes LC. Preoperative anxiety and postoperative pain in women undergoing hysterectomy. J Psychosom Res 2000;49(6):417–22. [CrossRef][PubMed]
Kelly D, Campbell P, Torrens C, Charalambous A, Östlund U, Eicher M, et al. The effectiveness of nurse-led interventions for cancer symptom management 2000–2018: a systematic review and meta-analysis. Heal Sci Rev 2022;4:100052. [CrossRef]
Krebber AMH, Buffart LM, Kleijn G, Riepma IC, de Bree R, Leemans CR, et al. Prevalence of depression in cancer patients: a meta-analysis of diagnostic interviews and self-report instruments. Psycho Oncol 2014;23(2):121–30. [CrossRef][PubMed]
Lee Y, Lim MC, Kim SI, Joo J, Lee DO, Park SY. Comparison of quality of life and sexuality between cervical cancer survivors and healthy women. Cancer Res Treat 2016;48(4):1321–9. [CrossRef][PubMed]
Lemogne C, Niedhammer I, Khlat M, Ravaud JF, Guillemin F, Consoli SM, et al. Gender differences in the association between depressive mood and mortality: a 12-year follow-up population-based study. J Affect Disord 2012;136(3):267-75. [CrossRef][PubMed]
Li H, Wu X, Cheng X. Advances in diagnosis and treatment of metastatic cervical cancer. J Gynecol Oncol 2016;27(4):e43. [CrossRef][PubMed]
Li LJ, Chen Q, Zhang N, Yao X, Wang CX. Use of antidepressants following hysterectomy with or without oophorectomy: A national sample in the US. Maturitas 2023;167:32-8. [CrossRef][PubMed]
Linden AH, Hönekopp J. Heterogeneity of research results: a new perspective from which to assess and promote progress in psychological science. Perspect Psychol Sci 2021;16(2):358–76. [CrossRef][PubMed]
Mantegna G, Petrillo M, Fuoco G, Venditti L, Terzano S, Anchora LP, et al. Long-term prospective longitudinal evaluation of emotional distress and quality of life in cervical cancer patients who remained disease-free 2-years from diagnosis. BMC Cancer 2013;13:127. [CrossRef][PubMed]
Mayadev JS, Ke G, Mahantshetty U, Pereira MD, Tarnawski R, Toita T. Global challenges of radiotherapy for the treatment of locally advanced cervical cancer. Int J Gynecol Cancer 2022;32(3):436-45. [CrossRef][PubMed]
McQuellon RP, Wells M, Hofman S, Craven KB, Russel KG, Gruz J. Reducing distress in cancer patients with an orientation program. Psycho-Oncology 1998;7:207-17. [CrossRef][PubMed]
Mendlowicz MV, Stein MB. Quality of life in individuals with anxiety disorders. Am J of Psychiatry 2000;157:669-82. [CrossRef][PubMed]
Peterson RW, Graham G, Quinlivan JA. Psychological changes after a gynecologic cancer. J Obstet Gynaecol Res 2005;31(2):152-7. [CrossRef][PubMed]
Pinquart M, Duberstein PR. Depression and cancer mortality: a meta-analysis. Psychol Med 2010;40(11):1797-810. [CrossRef][PubMed]
Shyu IL, Hu LY, Chen YJ, Wang PH, Huang BS. Risk factors for developing depression in women with cervical cancer: a nationwide population-based study in Taiwan. Int J Womens Health 2019:11:135-41. [CrossRef][PubMed]
Tosic Golubovic S, Binic I, Krtinic D, Djordjevic V, Conic I, Gugleta U, et al. Risk Factors and Predictive Value of Depression and Anxiety in Cervical Cancer Patients. Medicina (Kaunas) 2022;58(4):507. [CrossRef][PubMed]
Vaz AF, Pinto-Neto AM, Conde DM, Costa-Paiva L, Moralis SS, Esteves SB. Quality of life of women with gynecologic cancer: associated factors. Arch Gynecol Obstet 2007;276(6):583-9. [CrossRef][PubMed]
Vistad I, Fossa SD, Kristensen GB, Dahi AA. Chronic fatigue and its correlates in long-term survivors of cervical cancer treated with radiotherapy. BJOG 2007;114(9):1150-8. [CrossRef][PubMed]
Wang F, Li CB, Li S, Li Q. Integrated interventions for improving negative emotions and stress reactions of young women receiving total hysterectomy. Int J Clin Exp Med 2014;7(1):331–6. [PubMed]
Yi Wu C, Chan TF , Shi HY, Kuo YL. Psychiatric problems of anxiety and depression disorder are associated with medical service utilization and survival among patients with cervical cancer. Taiwan J Obstet Gynecol 2021;60(3):474-9. [CrossRef][PubMed]
Zhao H, Zhao Z, Chen C. Prevalence, risk factors and prognostic value of anxiety and depression in cervical cancer patients underwent surgery. Transl Cancer Res 2020;9(1):65-74.[CrossRef][PubMed]
