Tumor mass in the lung with superior vena cava syndrome
Abstract
Group of symptoms due to vena cava superior obstruction is named superior vena cava syndrome. A 65-year-old female, long-standing smoker was presented with a two-week history of dry cough and facial swelling. The patient noticed a palpable mass on the right side of the neck. Computer tomography scan with contrast showed extensive, irregular, non-homogenous consolidation in the right upper lobe, involving the right hilus, surrounding the aortic arch, supra aortic branches and pleural effusion at the right side of the body. Also, ultrasound examination of supra clavicular space showed enlarged pathologic hypoehogenic lymph node without an echogenic hilum. Ultrasound guided fine needle biopsy of lymph node was performed, and cytopathology findings showed metastatic lesion from primary microcellular lung cancer, IIIC stadium, cT4N3M0. Venous angioplasty was performed showing stenosis in the superior vena cava. After balloon dilatation, the stent was placed at the site of stenosis. The patient received chemio- and radiotherapy and survival time was seven months. Superior vena cava syndrome is an urgent clinical condition, and lung cancer is the leading cause of this syndrome. Computer tomography imaging findings and endovascular stent
placement are important for detection and management of the superior vena cava thrombosis.
References
Friedman T, Quencer KB, Kishore SA, Winokur RS, Madoff DC. Malignant Venous Obstruction: Superior Vena Cava Syndrome and Beyond. Semin Intervent Radiol. 2017;34 (4):398.
Kalra M, Sen I, Gloviczki P. Endovenous and Operative Treatment of Superior Vena Cava Syndrome. Surg Clin North Am. 2018; 98 (2):321.
García Mónaco R, Bertoni H, Pallota G, Lastiri R, Varela M, Beveraggi EM, Vassallo BC. Use of self-expanding vascular endoprostheses in superior vena cava syndrome. Eur J Cardiothorac Surg. 2003;24(2):208.
Wilson LD, Detterbeck FC, Yahalom J. Superior Vena Cava Syndrome with Malignant Causes. N Engl J Med. 2007;356:1862-9.
Katabathina VS, Restrepo CS, Betancourt Cuellar SL et-al. Imaging of oncologic emergencies: what every radiologist should know. Radiographics. 2013;33 (6): 1533-53.
RE Drews, DJ Rabkin. Malignancy-related superior vena cava syndrome. Uptodate [journal on the Internet]. 2019 Jun 27 [cited 2020 Jan 20]. Available from: https://www.uptodate.com/contents/malignancy-related-superior-vena-cava-syndrome
Straka C, Ying J, Kong FM, Willey C, Kaminski J,Kim DW. Review of evolving etiologies, implications and treatment strategies for the superior vena cava syndrome. Springerplus. 2016; 29(5):229.
Rowell NP, Gleeson FV. Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus: a systematic review. Clin Oncol (R Coll Radiol). 2002;14(5):338.
Lepper PM, Ott SR, Hoppe H, Schumann C, Stammberger U, Bugalho A et al.Superior Vena Cava Syndrome in Thoracic Malignancies. Respiratory Care. 2011, 56 (5) 653-666.
Sonavane SK, Milner DM, Singh SP, Abdel Aal AK, Shahir KS, Chaturvedi A. Comprehensive Imaging Review of the Superior Vena Cava. Radiographics. 2015;35(7):1873-92.
Karakhanian WK., Karakhanian WZ, Belczak SQ. Superior vena cava syndrome: endovascular management. J Vasc Bras. 2019; 18: e20180062.