Nodular lesion in the tongue: a rare case of low grade myofibroblastic sarcoma

Jefferson Rocha Tenorio; Frederico Buhatem Medeiros; Suzana Sousa C. O. M. Sousa; Décio Santos Pinto-Júnior

doi:10.2298/AOO190827009T

Jefferson Rocha Tenorio Dentistry School of University os São Paulo Department of Oral Pathology
Frederico Buhatem Medeiros Department of Dentistry, Society of Cardiology of the State of São Paulo, and Hospital Samaritano of the State of São Paulo, São Paulo, Brazil.
Suzana Sousa C. O. M. Sousa Dentistry School of University os São Paulo Department of Oral Pathology
Décio Santos Pinto-Júnior Dentistry School of University os São Paulo Department of Oral Pathology

DOI: https://doi.org/10.2298/AOO190827009T

Keywords: Immunohistochemistry, Rare, Tongue, Sarcoma, Neoplasms, Diagnosis,

Abstract

Low grade myofibroblastic sarcoma is an atypical myofibroblastic malignant neoplasm that rarely affects the oral cavity and presents a challenging histological diagnosis. Here we report the case of a 38-year-old woman who had a nodular and symptomatic lesion on the lateral border of the tongue. After the biopsy, the histopathological analysis revealed a spindle cell lesion with fascicular and storiform pattern. We performed immunohistochemical analysis that showed intense labeling for vimentin, smooth muscle actin and moderate labeling for calponin and S-100. We emphasize the rarity of low grade myofibroblastic sarcoma such as a nodular lesion on the tongue and the need for accurate diagnosis.

Author Biographies

Jefferson Rocha Tenorio, Dentistry School of University os São Paulo Department of Oral Pathology

PhD student at Dentistry School of University os São PauloDepartment of Oral Pathology

Frederico Buhatem Medeiros, Department of Dentistry, Society of Cardiology of the State of São Paulo, and Hospital Samaritano of the State of São Paulo, São Paulo, Brazil.

PhD at Department of Dentistry, Society of Cardiology of the State of São Paulo, and Hospital Samaritano of the State of São Paulo, São Paulo, Brazil.

Suzana Sousa C. O. M. Sousa, Dentistry School of University os São Paulo Department of Oral Pathology

Professor at Dentistry School of University os São PauloDepartment of Oral Pathology

Décio Santos Pinto-Júnior, Dentistry School of University os São Paulo Department of Oral Pathology

Professor at Dentistry School of University os São PauloDepartment of Oral Pathology

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