Nodular lesion in the tongue: a rare case of low grade myofibroblastic sarcoma

  • Jefferson Rocha Tenorio Dentistry School of University os São Paulo Department of Oral Pathology
  • Frederico Buhatem Medeiros Department of Dentistry, Society of Cardiology of the State of São Paulo, and Hospital Samaritano of the State of São Paulo, São Paulo, Brazil.
  • Suzana Sousa C. O. M. Sousa Dentistry School of University os São Paulo Department of Oral Pathology
  • Décio Santos Pinto-Júnior Dentistry School of University os São Paulo Department of Oral Pathology
Keywords: Immunohistochemistry, Rare, Tongue, Sarcoma, Neoplasms, Diagnosis,

Abstract


Low grade myofibroblastic sarcoma is an atypical myofibroblastic malignant neoplasm that rarely affects the oral cavity and presents a challenging histological diagnosis. Here we report the case of a 38-year-old woman who had a nodular and symptomatic lesion on the lateral border of the tongue. After the biopsy, the histopathological analysis revealed a spindle cell lesion with fascicular and storiform pattern. We performed immunohistochemical analysis that showed intense labeling for vimentin, smooth muscle actin and moderate labeling for calponin and S-100. We emphasize the rarity of low grade myofibroblastic sarcoma such as a nodular lesion on the tongue and the need for accurate diagnosis.

Author Biographies

Jefferson Rocha Tenorio, Dentistry School of University os São Paulo Department of Oral Pathology
PhD student at Dentistry School of University os São PauloDepartment of Oral Pathology
Frederico Buhatem Medeiros, Department of Dentistry, Society of Cardiology of the State of São Paulo, and Hospital Samaritano of the State of São Paulo, São Paulo, Brazil.
PhD at Department of Dentistry, Society of Cardiology of the State of São Paulo,  and Hospital Samaritano of the State of São Paulo, São Paulo, Brazil.
Suzana Sousa C. O. M. Sousa, Dentistry School of University os São Paulo Department of Oral Pathology
Professor at Dentistry School of University os São PauloDepartment of Oral Pathology
Décio Santos Pinto-Júnior, Dentistry School of University os São Paulo Department of Oral Pathology
Professor at Dentistry School of University os São PauloDepartment of Oral Pathology

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Published
2019/10/16
Section
Short Report