POVEZANOST IZMEĐU LABORATORIJSKIH PARAMETARA I ISHODA LEČENJA KOD COVID-19

  • Ruzica Radojevic-Marjanovic 1- University Clinical Centre Kragujevac, Clinic for infectious and tropic diseases, Kragujevac, Serbia
  • Slobodan Jankovic 5- University of Kragujevac, Serbia, Faculty of Medical Sciences, Department of Pharmacology and toxicology
  • Kristijan Krstic 4- University of Kragujevac, Serbia, Faculty of Medical Sciences, Department of Physical medicine and rehabilitation
  • Valentina D Opancina Fakultet medicinskih nauka, Univerzitet u Kragujevcu
DOI: https://doi.org/10.5937/mckg54-31020
Ključne reči: COVID-19; laboratorija; albumini

Sažetak


Cilj. Cilj ove studije bio je da istraži osnovne karakteristike i korelaciju između C-reaktivnog proteina, D-dimera, Ferritina i albumina sa ishodom lečenja infekcije COVID-19.

Metode. Naše istraživanje je sprovedeno na Klinici za infektivne bolesti Univerzitetskog Kliničkog centra Kragujevac u periodu od 1. novembra 2020. do 1. februara 2021. Dizajnirano je kao serija slučajeva i obuhvatilo je pacijente starije od 18 godina sa pozitivnim  rezultatom PCR testa ili serološkog (antigenskog) test na SARS-COV-2, koji su lečeni u našoj klinici.

Rezultati. Pronađena je značajna korelacija između humanih serumskih albumina (g/L) sa ishodom lečenja p = 0,009, dok je koeficijent korelacije bio 0,466. Takođe niži nivo albumina bio je u značajnoj korelaciji sa intrahospitalnim mortalitetom, dok je p = 0,007 i koeficijent korelacije bio 0,484.

Zaključak. Rezultati našeg istraživanja sugerišu da bi hipoalbuminemija mogla da se koristi kao značajan prognostički faktor za intrahospitalni mortalitet kod pacijenata sa COVID-19.

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Objavljeno
2021/03/25
Broj časopisa
Vol. 54 Br. 4 (2020): MEDICINSKI ČASOPIS
Rubrika
Originalni naučni članak