Kongenitalna displazija mitralne valvule kod ženskog deteta:infektivni endokarditis ili nasledni poremećaj vezivnog tkiva

Jelena M Nestorovic Tanaskovic

doi:10.5937/mckg48-6133

Jelena M Nestorovic Tanaskovic Univerzitet u Kragujevcu Fakultet Medicinskih nauka

DOI: https://doi.org/10.5937/mckg48-6133

Sažetak

Uvod. Displastična ili miksomatozna mitralna valvula se karakteriše miksomatoznom degeneracijom kolagena i elastina koja dovodi do bujanja mitralnih zalistaka. Vremenom mogu da se razviju patološke karakrteristike, kao što je prolaps valvula sa značajnom regurgitacijom, a površinske abnormalnosti takvih zalistaka mogu da predisponiraju tromboembolijske komplikacije ili infektivni endokarditis.

Prikaz bolesnika. Kod devojčice uzrasta 3 godine i 7 meseci na osnovu anamneze, klničke slike i učinjenih ispitivanja postavljena je ozbiljna sumnja na infektivni endokarditis. Ispunjavala je prema Dukeovim kriterijumima: 1 major - pozitivan ehokardiografski nalaz na srcu, (prisustvo "veruke" na mitralnom aparatu) i 3 minor znaka - prolongirana febrilnost praćena groznicom, pozitivna jedna hemokultura i artralgije. Posle primene antibiotske terapije, kontrolni ehokardiagrafski nalaz je bio nepromenjen, laboratorijske analize u granicama normale, opšte stanje deteta dobro. Zato smo uzeli u razmatranje da se radi o miksomatoznoj degeneraciji mitralnog aparata, koja jako podseća na verukozne promene.

Zaključak. Na osnovu sličnih fenotipskih i ehokardiografskih karakteristika devojčice i njenog oca mišljenja smo da se radi o kongenitalnoj displaziji mitralne valvule, sa mogućim naslednim poremećajem vezivnog tkiva.

Ključne reči: kongenitalana displazija mitralne valvule, dete, nasledni poremećaji vezivnog tkiva.

Biografija autora

Jelena M Nestorovic Tanaskovic, Univerzitet u Kragujevcu Fakultet Medicinskih nauka

Dr Jelena Nestorović Tanasković, pedijatar zaposlena na Odeljenju intenzivne nege u Klinici za Pedijatriju KC Kragujevac

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