EVALUACIJA FAKTORA RIZIKA I PROCENA KVALITETA ŽIVOTA KOD PACIJENATA SA BAZOCELULARNIM KARCINOMOM

  • Stefan D Loncar Stomatoloski fakultet Beograd
  • Dragan S Loncar

Sažetak


Introduction: Basal cell skin cancer is a malignant tumor originating from the epithelium, which is in about 80% of cases develop in the head and neck.

Objective: To estimate the risk factors and quality of life in patients with cutaneous basal cell carcinoma of the head and neck.

Materials and Methods: The study was conducted in a prospective study. The study included 60 patients aged 40 to 87 years, who were diagnosed with basal cell skin cancers. In all patients who were included in this study was previously conducted surgical therapy. Assessment of risk factors was analyzed from bad habits and socio-economic status. The quality of life was used Skin Cancer Index (SCI). Values ​​SCI is numerically quantified on a scale from 0 to 100. For statistical analysis of data, the T-test, and χ2 test, p <0.05 (SPSS program).

Results: The consumption of alcohol was present in 45% of patients, while 32% of respondents said they consumed tobacco. Exposure to UV radiation was observed in 30% of patients. Evaluation SCI noted a decline in the quality of life in 90% of patients. In patients with the affected functional structures of the orofacial region total value of SCI was significantly lower than in those where they were not affected (p = 0.031).

The prevalence of bad habits and exposure to UV radiation in this study is in accordance with contemporary literature data. In patients with cutaneous basal cell carcinoma of the head and neck there is a decreased quality of life.

Keywords: Basal cell carcinoma, risk factors, quality of life

Biografije autora

Stefan D Loncar, Stomatoloski fakultet Beograd
student
Dragan S Loncar
dr sci med

Reference

The WHOQOL Group. The World Health Organizatio Quality of Life Assessment (WHOQOL): Position Paper From the World Health Organization. Social Science and Medicine1995;41(10):1403-9.

Miodrag Gavrić, Aleksa Piščević, Ivan Sjerobabin. Maksilofacijalna hirurgija, Beograd, 2001. Bazocelularni karcinom str. 369-371.

Peterson’s Principles of Oral and Maxillofacia Surgery, Secon Edition.

Ting PT, Kasper R, Arlette JP. Metastatic basal cell carcinoma: report of two cases and literature review. J Cutan Med Surg. 2005 Jan;9(1):10-5.

Teresa T. Fung,2 David J. Hunter, Donna Spiegelman, Graham A. Colditz, Eric B. Rimm, and Walter C. Willett. Intake of Alcohol and Alcoholic Beverages and the Risk of Basal Cell Carcinoma of the Skin. Cancer Epidemiology, Biomarkers & Prevention. Vol. 11, 1119–1122, October 2002.

D. Michal Freedman, Alice Sigurdson, Michele Morin Doody, Kiyohiko Mabuchi, and Martha S. Linet. Risk of Basal Cell Carcinoma in Relation to Alcohol Intake and Smoking. Cancer Epidemiology, Biomarkers & Prevention. Vol. 12, 1540–1543, December 2003.

John S. Rhee, MD, MPH, B. Alex Matthews, PhD, Marcy Neuburg, MD, Brent R. Logan, PhD, Mary Burzynski, RN, and Ann B. Nattinger, MD, MPH. Validation of a Quality-of-Life Instrument for Patients With Nonmelanoma Skin Cancer. Arch Facial Plast Surg. 2006 ; 8(5): 314–318.

John S. Rhee, MD, MPH, B. Alex Matthews, PhD, Marcy Neuburg, MD, Brent R. Logan, PhD, Mary Burzynski, RN, and Ann B. Nattinger, MD, MPH. The Skin Cancer Index: Clinical Responsiveness and Predictors of Quality of Life. Laryngoscope. 2007 March ; 117(3): 399–405.

George Radiotis, MA, Nicole Roberts, MEd, Zofia Czajkowska, MA, Manish Khanna, MD, FRCP(C), and Annett Körner, PhD. Nonmelanoma Skin Cancer:Disease-Specific Quality-of-Life Concerns and Distress. Oncology Nursing Forum. Vol. 41, No. 1, January 2014.

Paula Curitiba Maciel, Joel Veiga-Filho, Marcelo Prado de Carvalh, Fernando Elias Martins Fonseca, Lydia Masako Ferreira, Daniela Francescato Veig. Quality of life and self-esteem in patients submitted to surgical treatment of skin carcinomas: long-term results. An Bras Dermatol. 2014;89(4):594-8.

Rosamaria Corona, Eugenia Doglioti, Mariarosaria Erico, Francesco Serra, Ivano Lavarone, Luca Chinni, Tommaso Gabelo, Pietro Puddu, Paolo Pasquoino. Risk Factors for Basal Cell Carcinoma in a Mediterranean Population. Arch Dermatol. 2001; 137: 1162- 1168.

Tina Chen, MD; Daniel Bertenthal, MPH; Anju Sahay, PhD; Saunak Sen, PhD; Mary-Margaret Chren, MD. Predictors of Skin-Related Quality of Life After Treatment of Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma. Arch Dermatol. 2007;143(11):1386-139.

Moolenburgh SE, Mureau MA, Versnel SL, Duivenvoorden HJ, Hofer SO. The impact of nasal reconstruction following tumour resection on psychosocial functioning, a clinical- empirical exploration. Psychooncology. 2009;18:747-52.

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2016/01/24
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