https://aseestant.ceon.rs/index.php/medrec/issue/feedMedical Word2025-09-18T07:49:57+02:00Ana Antićdrana.antic@gmail.comSCIndeks Assistant<p>The journal Medicinska reč publishes papers from the field of biomedical sciences that have not been published before or submitted for publication in other journals.</p> <p>Publication frequency – one volume, four issues per year</p>https://aseestant.ceon.rs/index.php/medrec/article/view/61562Inflammatory Myofibroblastic Tumor of the Knee in a 7-year-old Child: A Case Report2025-09-18T07:49:57+02:00Aleksandar Jankovićaleksandar-jankovic@outlook.comZoran Marjanovićdrzmarjanovic@gmail.comNikola Bojovićniboj.nb@gmail.comNikola Vacićvacic1410@gmail.comDejana Božićdejana.bozic@imd.org.rs<p>Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm with intermediate malignant potential, typically occurring in children and young adults. We report a case of seven-year-old boy with a well-defined, extra-articular medial knee mass. MRI demonstrated a solid lesion with strong homogeneous enhancement without joint or bone invasion. Complete surgical excision was performed. Histopathology revealed myofibroblastic spindle-cell proliferation in a myxoid stroma with mixed inflammatory infiltrate. Immunohistochemistry showed SMA positivity and ALK negativity; molecular testing identified ROS1 rearrangement and COL1A1–PDGFRα fusion. The postoperative course was uneventful with no recurrence on follow-up. This case underscores the value of comprehensive molecular profiling in atypical IMT locations and the potential for targeted therapy in unresectable or recurrent disease. </p>2025-09-18T07:39:31+02:00Copyright (c) 2025 Medical Word