Medical Word

Editor’s note

2022-12-23T07:20:45+01:00

Dear colleagues and authors, dear readers,

Here is the fourth issue of the journal “Medical Word” which represents the collection of abstracts and introductory lectures submitted for the XV Congress of the National Association of Health Workers of Serbia, which was planned and accredited for October 2020, but because of the current epidemiological situation caused by the spread of the COVID-19 pandemic, it has been delayed. In this way, the Editorial Board of the journal expresses their gratitude and support to all health workers who were selfless and worked hard during the entire period of the pandemic. We sincerely hope that the conditions will be agreeable to the planned congress to be held, and for us to exchange the knowledge and experiences that we are transmitting to you in this issue of “Medical Word”.

We thank all the authors so far for their work. We also invite interested authors to submit their papers from the medical fields they deal with and also participate in the creation of our journal. In the end, thank you all, dear friends, for reading the journal all this time, noticing our efforts, and supporting us.

Until the next issue,

Prim. Ana Antić, MD, PhD,

Editor-in-chief

XV Congress of the National Association of Health Workers of Serbia - Abstracts

2022-12-23T07:20:46+01:00

Effects of aerosol from the Tobacco Heating System (THS) on human organotypic cultures of the aerodigestive tract

2022-12-23T07:20:46+01:00

Cigarette smoking is responsible for a multitude of health risks and is one of the major modifiable risk factors for many smoking-related diseases. Tobacco Heating System (THS) is an electronic device, which heats tobacco instead of burning it. The THS aerosol has a different chemical composition to cigarette smoke, with its levels of harmful and potentially harmful constituents reduced on average by 90-95%. Advances in tissue engineering have enabled the development of sophisticated, three-dimensional organotypic culture systems that closely resemble human physiology. In several recent studies, buccal, gingival, nasal, bronchial, and small airway human epithelial organotypic cultures were exposed to aerosol from the THS and cigarette smoke. Standard toxicological assays were combined with network-based systems toxicology analyses to identify otherwise undetectable cellular-level effects. The results showed that the THS aerosol has a minimal biological impact on cells in comparison to cigarette smoke.