Hemangioma of uterine cervix associated with high-grade squamous intraepithelial lesion

Matilda Djolai; Tamara Bošković; Srdjan Djurdjevic; Sandra Trivunić Dajko; Bojana Andrejić Višnjić; Ranko Rajović

doi:10.2298/4910

Matilda Djolai Clinical Center of Vojvodina, Novi Sad, Serbia; Department of Histology and Embryology, Medical Faculty, Novi Sad, University of Novi Sad, Novi Sad, Serbia
Tamara Bošković Clinical Center of Vojvodina, Novi Sad, Serbia; Department of Histology and Embryology, Medical Faculty, Novi Sad, University of Novi Sad, Novi Sad, Serbia
Srdjan Djurdjevic Clinical Center of Vojvodina, Novi Sad, Serbia; Department of Gynecology and Obstetrics, Medical Faculty, Novi Sad, University of Novi Sad, Novi Sad, Serbia
Sandra Trivunić Dajko Clinical Center of Vojvodina, Novi Sad, Serbia; Department of Pathology, Medical Faculty, Novi Sad, University of Novi Sad, Novi Sad, Serbia
Bojana Andrejić Višnjić Department of Histology and Embryology, Medical Faculty, Novi Sad, University of Novi Sad, Novi Sad, Serbia
Ranko Rajović Department of Science, Mensa Serbia, Center for Education NTC, Novi Sad, Serbia

DOI: https://doi.org/10.2298/4910

Keywords: cervix uteri, hemangioma, uterine cervical dysplasia, comorbidity,

Abstract

Introduction. Benign, especially polypoid, lesions of the cervix are common in everyday work. Rare tumors of this region are vascular ones, particularly capillary and/or cavernous hemangiomas. Cervical hemangiomas are especially rare, usually asymptomatic and only one third of the cases is clinically manifested as vaginal bleeding, polyps, etc. Case report. We reported a 54-year-old postmenopausal female patient who had undergone conization due to high-grade squamous intraepithelial lesion (H-SIL). Microscopic analysis of slices confirmed the existence of dysplastic changes in the endocervical epithelium and in small part in the epithelium of the gland of H-SIL type. In 2 of 15 slices, within the walls of the cervix, dilated, amplified and abnormal blood vessels lined with endothelium were observed, vaguely limited by the surrounding connective tissue of lamina propria and smooth muscle wall of the cervix. According to the pathological characteristics, the change corresponded to the hemangioma. Both changes were completely removed. Conclusion. In comparison with the available literature data, the presented case is the first to describe the association of hemangioma and dysplastic changes in the endocervical epithelium. Hemangioma was incidentally discovered in the histological sections of the material after the conization in a postmenopausal women.

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