AN ANALYSIS OF LABORATORY PARAMETERS OF CHRONIC KIDNEY FAILURE IN ELDERLY PATIENTS
Abstract
Aim: The main aim of this study is monitoring of laboratory parameters of chronic kidney failure in elderly patients.
Materials and methods: All samples were taken and processed by standard methods and according to the principles of good laboratory practice. Data were collected in an organized and systematic manner in the form of a questionnaire with respect to ethical principles and as such were analyzed by statistical tests and analyzes (Student t test, analysis of variance - ANOVA, Pearson and Spearman correlation coefficient). The limit of statistical significance is P <0.05.
Results: Mean values of creatinine clearance and proteinuria for the total study population were: 41.30 ± 21.43 mL/min, 1.5 ± 2.3 g/L/24h, respectively. Hematological parameters did not show significant differences from normal values. The highest frequency of comorbidities was observed in subjects aged ≥80 years with an average of 2.03 comorbidities per subject. Serum creatinine and urea values as well as creatinine clearance are good indicators of disease progression.
Conclusion: The results of the presented research suggest that old age is a predisposing risk factor for the development of chronic kidney disease, and that in combination with comorbidities (hypertension and/or diabetes) it contributes to poor prognosis or disease progression.
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