INFLUENCE OF PSYCHOACTIVE SUBSTANCES ON NEPHROTOXICITY OF THE KIDNEYS

Psychoactive substances and kidneys

  • Radojica Stolić Univerzitet u Kragujevcu Fakultet medicinskih nauka
  • Marija University of Pristina Settled in Kosovska Mitrovica, Faculty of Medicine, Kosovska Mitrovica, Serbia
  • Vekoslav University of East Sarajevo, Faculty of Medicine Foca, Republika Srpska, Bosnia and Herzegovina
  • Andrijana University of Pristina Settled in Kosovska Mitrovica, Faculty of Medicine, Kosovska Mitrovica, Serbia
  • Kristina University of Pristina Settled in Kosovska Mitrovica, Faculty of Medicine, Kosovska Mitrovica, Serbia
  • Dragisa University of Pristina Settled in Kosovska Mitrovica, Faculty of Medicine, Kosovska Mitrovica, Serbia
  • Milica University Clinical Center Kragujevac, Clinical for Nephrology and Dialysis, Serbia
  • Branka University of Nis, Serbia, Faculty of Medicine Nis, Department of Internal Medicine-Nephrology, Faculty of Medicine, Serbia
DOI: https://doi.org/10.5937/afmnai41-46097
Keywords: Abuse, Psychoactive substances, Kidney disease, Nephrotoxicity, Complications

Abstract


Background: The metabolism and effects of the abuse of psychoactive substances are not yet fully understood, but it is evident that they represent a tremendous risk to the health of individuals.

Aim: This narrative review aims to present a summary of published results on the impact of psychoactive substance abuse on kidney function.

Methodology: PubMed and MEDLINE databases were used to search the literature related to drug abuse and their effects on renal function.

Results: For this study we found 79 human studies which aimed to present a summary of published results on the impact of psychoactive substance abuse on kidney function. Renal manifestations of specific illicit drug abuse were included in this review.

Conclusion: Understanding the nephrotoxicological profile caused by the use of psychoactive substances is the basis for adequate risk assessment and improvement of the treatment of the consequential kidney disorders.

Published
2025/11/20
Issue
Vol. 41 No. 2 (2024): Acta facultatis medicae Naissensis
Section
Pregledni rad / Review article