OVARIAN CANCER INCIDENCE TREND IN THE NIŠAVA DISTRICT

  • Biljana Kocic
Ključne reči: rak jajnika, incidencija, trend

Sažetak


Rak jajnika je na trećem mestu u svetu po učestalosti i sa najvećim letalitetom među ginekološkim malignitetima. Cilj rada bio je da se analizira trend incidencije raka jajnika u Nišavskom okrugu u periodu 1999-2017. Primenjen je deskriptivni epidemiološki metod. Izvor podataka bio je Registar za rak Instituta za javno zdravlje Niš i Populacioni registar za rak Srbije. Izračunavan je linearni trend nestandardizovanih i standardizovanih stopa incidencije (na 100,000 žena). Standardizacija je vršena direktnom metodom. U strukturi svih malignih bolesti žena rak jajnika čini 5,1% sa 791 novoregistrovanim slučajem. Bolest se ne registruje u uzrastu pre 15. godine. Registruje se statistički značajan porast trenda sa uzrastom. Prosečna godišnja nestandardizovana stopa incidencije iznosi 22,0/100,000, dok standardizovana iznosi 13,3/100,000 žena. Najviša standardizovana stopa incidencije beleži se 2016 (20,4) a najniža 2020 (10,1). Registruje se porast trenda nestandardizovanih i standardizovanih stopa incidencije. Najviša standardizovana stopa incidencije beleži se u opštini Svrljig (18,4) i Gadžin Han (14,0) a najniža u opštini Merošina (7,4) i Doljevac (9,0). Registrovanje nepovoljnog trenda incidencije ovog oboljenja ukazuje na nedovoljno sprovođenje mera primarne i sekundarne prevencije u ranijem periodu  te je neophodno intenzivnije i obuhvatnije sprovoditi ove aktivnosti koje će redukovati faktore rizika i omogućiti rano otkrivanje bolesti.

Reference

Alberg AJ, Moorman PG, Crankshaw S, Wang F, Bandera EV, Barnholtz-Sloan JS, et al. Socioeconomic status in relation to the risk of ovarian cancer in African-American Women:a population-based case-control study. Am J Epidemiol 2016;184(4):274-83. [CrossRef] [PubMed]

Antonijevic A, Rancic N, Ilic M, Tiodorovic B, Stojanovic M, Stefanovic J. Incidence and mortality trends of ovarian cancer in central Serbia. JBUON 2017;22(2):508-12. [PubMed]

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68 (6): 394-424. [CrossRef] [PubMed]

Bray F, Loos AH, Tognazzo S, La Vecchia C. Ovarian cancer in Europe: crosssectional trends in incidence and mortality in 28 countries, 1953-2000. Int J Cancer 2005;113(6):977-90. [CrossRef] [PubMed]

Coburn S, Bray F, Sherman M, Trabert B. Interna-tional patterns and trends in ovarian cancer incidence, overall and by histologic subtype. Int J Cancer 2017; 140(11):2451-60. [CrossRef] [PubMed]

Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J Rosso S, Coebergh JW, Comber H, et al. Cancer incidence and mortality patterns in Europe:estimates for 40 countries in 2012. Eur J Cancer 2013;49:1374-403. [CrossRef] [PubMed]

Isherwood A, Bamford J, Dupuy AV. Ovarian cancer in select EU countries: incidence, treatable populations and sales by key drug class. Rev Epidemiol Sante Publique 2018;66:S286. [CrossRef]

Lowe KA, Chia VM, Taylor A, O'Malley C, Kelsh M, Mohamed M, et al. An international assessment of ovarian cancer incidence and mortality. Gynecol Oncol 2013;130(1):107-14. [CrossRef] [PubMed]

Momenimovahed Z , Tiznobaik A, Taheri S, Salehiniya H. Ovarian cancer in the world: epidemiology and risk factors. Int J Womens Health 2019;11:287-99. [CrossRef] [PubMed]

Praestegaard C, Kjaer SK, Nielsen TS, Jensen SM, Webb PM, Nagle CM, et al. The association between socioeconomic status and tumour stage at diagnosis of ovarian cancer: A pooled analysis of 18 case-control studies. Cancer Epidemiol 2016;41:71-9. [CrossRef] [PubMed]

Rahmani K, Moradi-Lakeh M, Mansori K, Bidokhti F, Asadi-Lari M. Global inequalities in incidence and mortality of ovarian cancer and associated factors: an ecological study. Alzheimers Park Res Ther 2018; 1: 1001.

Razi S, Ghoncheh M, Mohammadian-Hafshejani A, Aziznejhad H, Mohammadian M, Salehiniya H. The incidence and mortality of ovarian cancer and their relationship with the human development index in Asia. Cancermedicalscience 2016;10:628. [CrossRef] [PubMed]

Yoneda A, Lendorf ME, Couchman JR, Multhaupt HA. Breast and ovarian cancers: a survey and possible roles for the cell surface heparan sulfate proteo-glycans. J Histochem Cytochem 2012;60(1):9-21. [CrossRef] [PubMed]

Zhang Y, Luo G, Li M, Guo P, Xiao Y, Ji H, et al. Global patterns and trends in ovarian cancer incidence: age, period and birth cohort analysis. BMC Cancer 2019; 19:984. [CrossRef] [PubMed]

Objavljeno
2021/03/17
Rubrika
Originalni rad