ATOPIJSKI DERMATITIS
Sažetak
Atopijski dermatitis je hronična, nezarazna, multifaktorijalna upalna dermatoza sa pruritusom kao glavnim nalazom. Patofiziologija atopijskog dermatitisa je kompleksna. Uključuje genetske poremećaje, defekt epidermalne barijere, izmenjen imuni odgovor i poremećaj mikrobne ravnoteže kože, koji oštećuju epidermis izazivajući lezije kože sa svrabom. Prevalencija varira, ali je generalno prisutan kod 15% ‒ 30% dece, a 85% slučajeva manifestuje se pre pete godine života. Atopijski dermatitis, alergijski rinitis i astma čine trijadu atopičnih bolesti. Retrospektivnom analizom dokumentacije dece koja su lečena na Klinici za pedijatriju Univerzitetskog kliničkog centra Niš u periodu od 2018. do 2019. godine analizirani su anamnestički podaci, kliničke manifestacije i laboratorijski parametri dobijeni iz medicinske dokumentacije ispitanika. Ukupan broj ispitivane dece je 40 ‒ 21 ispitanik bio je muškog pola, a njih 19 bilo je ženskog pola. Podeljeni su u tri grupe po uzrastu (od dva meseca do sedam godina). Anamnestički podaci ukazuju na postojanje udruženosti AD sa drugim poremećajima po tipu atopijskih bolesti ‒ astmom, alergijskim rinitom, respiratornim infekcijama i alergijama na mleko.
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