HUMAN PAPILLOMAVIRUS: A CROSS-SECTIONAL SURVEY ON KNOWLEDGE AND ATTITUDES AMONG STUDENTS OF UNDERGRADUATE HEALTH STUDIES

  • Irma Salimović-Bešić Clinical Center of the University of Sarajevo, Unit for Clinical Microbiology
  • Selma Mujkić
  • Arzija Pašalić
Keywords: human papillomavirus, papillomavirus infection; students, vaccination, surveys, questionnaires

Abstract


The study aimed to assess the knowledge and attitudes of future healthcare professionals in Bosnia and Herzegovina (BIH) regarding the nature of human papillomavirus (HPV), HPV testing, and vaccination.

This descriptive-analytical, prospective, cross-sectional survey was conducted using a standardised questionnaire among students in the first and third year of undergraduate studies considering different study programs at the Faculty of Health Studies, University of Sarajevo.

The research resulted in 110 fully completed questionnaires. The percentage of students who had heard about HPV was 88.9% in the first year and 92.3% in the third year of health studies. Third-year students had better general knowledge of HPV (p = 0.007) and attitudes toward HPV testing (p = 0.009). Significant differences were in general knowledge of HPV among students of all study programs (p < 0.001) and in the knowledge of HPV testing (p = 0.001) and vaccination (p = 0.001). Health Care and Physiotherapy students had more knowledge and better attitudes when compared with other study programs.

The level of knowledge about HPV infection among students in BIH is low regardless of study year and program. Targeted interventions in health education could have a positive impact on spreading knowledge about HPV and adopting preventive methods in the future.

References

George C, Roberts R, Brennen D, Deveaux L, Read SE. Knowledge and awareness of Human Papillomavirus (HPV) and HPV vaccines among Caribbean youth: the case of the Bahamas. Hum Vaccin Immunother 2020;16(3):573-80. [CrossRef] [PubMed]

Alba A, Cararach M, Rodriguez-Cardeira C. The human papillomavirus (HPV) in human pathology: description, pathogenesis, oncogenic role, epidemiology, and detection techniques. The Open Dermatology Journal 2009;3:90-102. [CrossRef]

Badgujar VB, Fadzil FSA, Singh HKB, Sami F, Badgujar S, Ansari MT. Knowledge, understanding, attitude, perception, and views on HPV infection and vaccination among health care students and professionals in Malaysia. Hum Vaccin Immunother 2019;15(1):156-62. [CrossRef] [PubMed]

Brendle SA, Bywaters SM, Christensen ND. Pathogenesis of infection by human papillomavirus. Curr Probl Dermatol 2014;45:47-57. [CrossRef] [PubMed]

Bzhalava D, Eklund C, Dillner J. International standardization and classification of human papillomavirus types. Virology 2015;476:341-4. [CrossRef] [PubMed]

Castle PE, Sadorra M, Lau T, Aldrich C, Garcia FAR, Kornegay J. Evaluation of a prototype real-time PCR assay for carcinogenic human papillomavirus (HPV) detection and simultaneous HPV genotype 16 (HPV16) and HPV18 genotyping. J Clin Microbiol 2009;47(10):3344-7. [CrossRef] [PubMed]

Cuschieri K, Ronco G, Lorincz A, Smith L, Ogilvie H, Mirabello L, et al. Eurogin roadmap 2017: Triage strategies for the management of HPV-positive women in cervical screening programs. Int J Cancer 2018; 143(4):735-45. [CrossRef] [PubMed]

Doorbar J, Egawa N, Griffin H, Kranjec C, Murakami I. Human papillomavirus molecular biology and disease association. Rev Med Virol 2015;25:2-23. [CrossRef] [PubMed]

Durusoy R, Yamazhan M, Taşbakan MI, Ergin I, Aysin M, Pullukçu H et al. HPV Vaccine awareness and willingness of first-year students entering the University of Western Turkey. Asian Pac J Cancer Prev 2010;11:1-7. [PubMed]

Egawa N, Egawa K, Griffin H, Doorbar J. Human papillomaviruses; epithelial tropisms, and the development of neoplasia. Viruses 2015;7(7):3863-90. [CrossRef] [PubMed]

Ferlay J, Colombet M, Soerjomataram I, Mathers C, Parkin DM, Pineros M, et al. Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods. Int J Cancer 2019;144(8):1941-53. [CrossRef] [PubMed]

Harper DM, DeMars LR. HPV vaccines – A review of the first decade. Gynecol Oncol 2017;146(1):196-204. [CrossRef] [PubMed]

Herbert J, Coffin J. Reducing patient risk for human papillomavirus infection and cervical cancer. J Am Osteopath Assoc 2008;108(2):65-70. [PubMed]

Keser G, Yilmazy G, Pekiner FN. Assessment of knowledge level and awareness about human papillomavirus among dental students. J Cancer Educ 2021;36(4):664-9. [PubMed]

Khan TM, Buksh MA, Rehman IU, Saleem A. Knowledge, attitudes, and perception towards human papillomavirus among university students in Pakistan. Papillomavirus Res 2016;2:122-7. [CrossRef] [PubMed]

Kops NL, Hohenberger GF, Bessel M, Horvath JDC, Domingues C, Maranhao AGK, et al. Knowledge about HPV and vaccination among young adult men and women: Results of a national survey. Papillomavirus Res 2019;7:123-8. [CrossRef] [PubMed]

Mahmutović Vranić S, Ademović E, Šeremet M, Jusić A, Vukaš E. Sexual behaviors toward sexually transmitted infections: A cross-sectional survey among undergraduate medical students. HealthMED Journal 2013;7(7):2208.

Mahmutović Vranić S, Aljičević M, Šegalo S, Jogunčić A. Knowledge and attitudes of sexually transmitted infections among high school students in Sarajevo. Acta Med Acad 2019;48(2):147-58. [CrossRef] [PubMed]

Martin E, Senior N, Abdullah A, Brown J, Collings S, Racktoo S, et al. Perceptions of HPV vaccine amongst UK university students. Health Education 2011;111(6):498-513. [CrossRef]

Matranga D, Lumia C, Gurneri R, Arculeo VM, Noto M, Pivetti A, et al. The vaccination & Hpv Knowledge (THinK) questionnaire: A reliability and validity study on a sample of women living in Sicily (southern-Italy). PeerJ 2019;7:e6254. [CrossRef] [PubMed]

Morshed K, Gruszka-Polz D, Szymanski M, Polz-Dacewicz M. Human papillomavirus (HPV) – Structure, epidemiology, and pathogenesis. Otolaryngol Pol 2014;68(5):213-9. [CrossRef] [PubMed]

Pando MA, Balan IC, Marone R, Dolezal C, Leu CS, Squiquera L, et al. HIV and other sexually transmitted infections among men who have sex with men recruited by RDS in Buenos Aires, Argentina: High HIV and HPV infection. PLoS One 2012;7(6):e39834. [CrossRef] [PubMed]

Salimović-Bešić I, Hukić M. Potential coverage of circulating HPV types by current and developing vaccines in a group of women in Bosnia and Herzegovina with abnormal Pap smears. Epidemiol Infect 2015;143(12):2604-12. [CrossRef] [PubMed]

Salimović-Bešić I, Tomić-Čiča A, Hukić M. Genotyping test based on viral DNA, RNA or both as a management option for high-risk human papillomavirus positive women: a cross-sectional study. Med Glas (Zenica) 2019;16(2):172-8. [CrossRef] [PubMed]

Selak S, Jurić V, Hren D, Jurić M. What do young people from Mostar, Bosnia and Herzegovina know about contraception and sexual health? Croat Med J 2004;45(1):44-9. [PubMed]

Sorbye SW, Suhrke P, Reva BW, Berland J, Maurseth RJ, Al-Shibli K. Accuracy of cervical cytology: Comparisons of diagnosis of 100 Pap smears read by four pathologists at three hospitals in Norway. BMC Clin Pathol 2017;17:18. [CrossRef] [PubMed]

Swarnapriya K, Kavitha D, Reddy GMM. Knowledge, attitude and practices regarding HPV vaccination among medical and paramedical students, India a cross-sectional study. Asian Pac J Cancer Prev 2015;16(18):8473-7. [CrossRef] [PubMed]

Trucchi C, Amicizia D, Tafuri S, Sticchi L, Durando P, Constantino C, et al. Assessment of knowledge, attitudes, and propensity towards HPV vaccine of young adult students in Italy. Vaccines 2020;8(1):74. [CrossRef] [PubMed]

Voidăzan S, Morariu SH, Tarcea M, Moldovan H, Curticăpian I, Dobreanu M. Human papillomavirus (HPV) infection and HPV vaccination: Assessing the level of knowledge among students of the University of Medicine and Pharmacy of Tĭrgu Mureş, Romania. Acta Dermatovenerol Croat 2016;24(3):193-202. [PubMed]

Waller J, Ostini R, Marlow LAV, McCaffery K, Zimet G. Validation of a measure of knowledge about human papillomavirus (HPV) using item response theory and classical test theory. Prev Med 2013;56(1):35-40. [CrossRef] [PubMed]

Wang R, Guo XL, Wisman GBA, Shuuring E, Wang WF, Zeng ZY, et al. Nationwide prevalence of human papillomavirus infection and viral genotype distribution in 37 cities in China. BMC Infect Dis 2015;15:257. [CrossRef] [PubMed]

Zhao FH, Tiggelaar SM, Hu SY, Zhao N, Hong Y, Niyazi M, et al. A multi-center survey of HPV knowledge and attitudes toward HPV vaccination among women, government officials, and medical personnel in China. Asian Pac J Cancer Prev 2012;13(5):2369-78. [CrossRef] [PubMed]

Published
2024/07/03
Section
Original article