GUIDELINES FOR MONITORING WOMEN WITH COAGULATION DISORDERS
Abstract
Irrespective of the progress in the recognition and treatment of women who suffer from bleeding disorders, modern medical science has yet to adjust the diagnosis, therapy and care to their needs. An increasing number of women are being diagnosed with the mentioned disorders. Some who consult a gynaecologist owing to heavy menstrual bleeding actually have a coagulation disorder. Failure to recognise this disorder is widespread. Heavy menstrual bleeding is a condition that women with such disorders experience from the onset of the reproductive period. It affects their quality of life. What is more, they face the problem of accepting the potential risks of transmitting the disease to their child. Timely recognition and registration of these patients are essential. It is important to talk with and consult healthcare professionals, as well as to prescribe adequate therapy that enables physicians to cope with the various needs of women during the reproductive period.
References
ACOG Committee on Practice Bulletins--Gynecology. ACOG practice bulletin: management of anovulatory bleeding. Int J Gynaecol Obstet 2001; 72(3):263-71. [CrossRef][PubMed]
American College of Obstetricians and Gynecologists. ACOG committee opinion no. 557: Management of acute abnormal uterine bleeding in nonpregnant reproductive-aged women. Obstet Gynecol 2013; 121(4):891-6. [CrossRef][PubMed]
American College of Obstetricians and Gynecologists. Screening and Management of Bleeding Disorders in Adolescents With Heavy Menstrual Bleeding: ACOG COMMITTEE OPINION, Number 785. Obstet Gynecol 2019; 134(3):e71-e83. [CrossRef][PubMed]
Bradley LD, Gueye NA. The medical management of abnormal uterine bleeding in reproductive-aged women. Am J Obstet Gynecol 2016; 214(1):31-44. [CrossRef][PubMed]
Chi C, Pollard D, Tuddenham EG, Kadir RA. Menorrhagia in adolescents with inherited bleeding disorders. J Pediatr Adolesc Gynecol 2010; 23(4):215-22. [CrossRef][PubMed]
Elmaoğulları S, Aycan Z. Abnormal Uterine Bleeding in Adolescents. J Clin Res Pediatr Endocrinol 2018; 10(3):191-7. [CrossRef][PubMed]
James AH. Von Willebrand disease. Obstet Gynecol Surv 2006; 61(2):136-45. [CrossRef][PubMed]
James AH. Women and bleeding disorders. Haemophilia 2010; 16:160-7. [CrossRef][PubMed]
Kadir RA, Edlund M, Von Mackensen S. The impact of menstrual disorders on quality of life in women with inherited bleeding disorders. Haemophilia 2010; 16:832-9. [CrossRef][PubMed]
Kadir RA, Lukes AS, Kouides PA, Fernandez H, Goudemand J. Management of excessive menstrual bleeding in woman with hemostatic disorders. Fertil Steril 2005; 84(5):1352-9. [CrossRef][PubMed]
Kirtava A, Drews C, Lally C, Dilley A, Evatt B. Medical, reproductive and psychosocial experiences of women diagnosed with von Willebrand’s disease receiving care in haemophilia treatment centres: a case-control study. Haemophilia 2003; 9:292–7. [CrossRef][PubMed]
Lacroix AE, Gondal H, Shumway KR, Langaker MD. Physiology, Menarche. [Updated 2022 Mar 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 ‘’cited 2022 October 12’’. Available from: URL: https://www.ncbi.nlm.nih.gov/books/NBK470216/ [PubMed]
Munro MG, Critchley HO, Broder MS, Fraser IS; FIGO Working Group on Menstrual Disorders. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. Int J Gynaecol Obstet 2011; 113(1):3-13. [CrossRef][PubMed]
Plu-Bureau G, Horellou MH. Prise en charge thérapeutique des ménométrorragies liées aux coagulopathies et traitement anticoagulant [Therapeutic management of menometrorrhagia in hemostasis disorders]. J Gynecol Obstet Biol Reprod (Paris) 2008; 37(8):S365-7. French. [CrossRef][PubMed]
Van Galen K, Lavin M, Skouw-Rasmussen N, Fischer K, Noone D, Pollard D, et al; European Haemophilia Consortium (EHC) and the European Association for Haemophilia and Allied Disorders (EAHAD). European principles of care for women and girls with inherited bleeding disorders. Haemophilia 2021; 27(5):837-47. [CrossRef][PubMed]
