PAIN MANAGEMENT OF SENSORIMOTOR POLYNEUROPATHY IN COVID-19 INFECTIONS
Abstract
A 73-year-old man has tested positive for SARS-CoV-2. On the tenth day of the disease, a symmetrical distribution of spontaneous pain and dysesthesia occurs in both feet. Initial pain management, ordered by general practitioner was not effective, so he was referred to the pain specialist. The new therapy included combination of anticonvulsants, antidepressants and adjuvant therapy with partial, but satisfactory reduction in pain. Education/reeducation of general practitioners would accelerate the detection and symptomatic treatment in the early stages of COVID-19. An even better suggestion would be to refer these patients to pain medicine specialists.
References
Abdelnour L, Eltahir Abdalla M, Babiker S. COVID 19 infection presenting as motor peripheral neuropathy. J Formos Med Assoc 2020;119(6):1119-20. [CrossRef][PubMed]
Binder A, Baron R. The Pharmacological Therapy of Chronic Neuropathic Pain. Dtsch Arztebl Int 2016;113(37):616-25. [CrossRef][PubMed]
Bureau BL, Obeidat A, Dhariwal MS, Jha P. Peripheral Neuropathy as a Complication of SARS-Cov-2. Cureus 2020;12(11):e11452. [CrossRef][PubMed]
Córdova-Martínez A, Caballero-García A, Pérez-Valdecantos D, Roche E, Noriega-González DC. Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment. Biomedicines 2022;10(5):1051. [CrossRef][PubMed]
Córdova-Martínez A, Caballero-García A, Pérez-Valdecantos D, Roche E, Noriega-González DC. Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment. Biomedicines. 2022;10(5):1051.
Correia AO, Feitosa PWG, Moreira JLS, Nogueira SÁR, Fonseca RB, Nobre MEP. Neurological manifestations of COVID-19 and other coronaviruses: A systematic review. Neurol Psychiatry Brain Res 2020;37:27-32. [CrossRef][PubMed]
Dai W, Zhang B, Jiang XM, Su H, Li J, Zhao Y, et al. Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Science 2020;368(6497):1331-5. [CrossRef][PubMed]
Dai W, Zhang B, Jiang XM, Su H, Li J, Zhao Y, et al. Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Science. 2020;368(6497):1331-1335.
Dragomanova S, Miteva S, Nicoletti F, Mangano K, Fagone P, Pricoco S, et al. Therapeutic Potential of Alpha-Lipoic Acid in Viral Infections, including COVID-19. Antioxidants (Basel) 2021;10(8):1294. [CrossRef][PubMed]
Drożdżal S, Rosik J, Lechowicz K, Machaj F, Szostak B, Majewski P, et al. COVID-19: Pain Management in Patients with SARS-CoV-2 Infection-Molecular Mechanisms, Challenges, and Perspectives. Brain Sci 2020;10(7):465. [CrossRef][PubMed]
Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, et al. Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol 2015;14(2):162-73. [CrossRef][PubMed]
Garg RK. Spectrum of Neurological Manifestations in Covid-19: A Review. Neurol India 2020;68(3):560-72. [CrossRef][PubMed]
Lai CC, Ko WC, Lee PI, Jean SS, Hsueh PR. Extra-respiratory manifestations of COVID-19. Int J Antimicrob Agents 2020;56(2):106024. [CrossRef][PubMed]
Lunn MP, Hughes RA, Wiffen PJ. Duloxetine for treating painful neuropathy or chronic pain. Cochrane Database Syst Rev 2009;(4):CD007115. [CrossRef][PubMed]
Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, et al. Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China. JAMA Neurol 2020;77(6):683-90. [CrossRef][PubMed]
Rifino N, Censori B, Agazzi E, Alimonti D, Bonito V, Camera G, et al. Neurologic manifestations in 1760 COVID-19 patients admitted to Papa Giovanni XXIII Hospital, Bergamo, Italy. J Neurol 2021;268(7):2331-8. [CrossRef][PubMed]
Suh J, Mukerji SS, Collens SI, Padera RF Jr, Pinkus GS, Amato AA, et al. Skeletal Muscle and Peripheral Nerve Histopathology in COVID-19. Neurology 2021;97(8):e849-e858. [CrossRef][PubMed]
Vo T, Rice ASC, Dworkin RH. Non‐steroidal anti‐inflammatory drugs for neuropathic pain: How do we explain continued widespread use?. Pain 2009;143(3):169‐71. [CrossRef][PubMed]
Yachou Y, El Idrissi A, Belapasov V, Ait Benali S. Neuroinvasion, neurotropic, and neuroinflammatory events of SARS-CoV-2: understanding the neurological manifestations in COVID-19 patients. Neurol Sci 2020;41(10):2657-69. [CrossRef][PubMed]