CERVICOBRACHIAL SYNDROME: PREVALENCE AND CLINICAL CORRELATION WITH CORONAVIRUS 2019 DISEASE AMONG HOSPITALIZED PATIENTS

Keywords: coronavirus disease 2019, cervical pain, cervicobrachial neuralgia, coronavirus disease 2019 vaccines, neutrophil-to-lymphocyte ratio

Abstract


There are currently emerging concerns about the multisystem involvement of the coronavirus disease 2019 (COVID-19) infection as well as potential long-term complications. The aim of our study was to examine the prevalence and clinical characteristics of cervicobrachial syndrome among hospitalized patients with  COVID-19. The research was conducted as a prospective study on 147 patients with previously confirmed COVID-19 infection by using a Real-Time Polymerase Chain Reaction assay for SARS-Cov-2. After neurological assessment and meticulous patient history-taking, the patients were divided into a group with and a group without a previous history of cervicobrachialgia. The pain intensity was self-assessed by patients using a numerical scale ranging from 0 to 10, while routine laboratory analyzes related to COVID-19 were performed from venous blood samples. Our data demonstrate a statistically significant association between previous history and recurrence of cervicobrachialgia (LR = 28.655; p = 0.000). Moreover, the pain intensity assessment in patients with a previous history of cervicobrachialgia statistically significantly correlates with the current degree of cervicobrachialgia during hospitalization (p = 0.000). Furthermore, a weak positive correlation (r = 0.168; p = 0.046) was noted between the current degree of cervicobrachiialgia and the neutrophil to lymphocyte ratio. The present study demonstrates a statistically significant association between the previous history of cervicobrachial syndrome and its recurrence, as well as pain intensity assessment in hospitalized patients due to COVID-19. The neutrophil-to-lymphocyte ratio positively correlates with the  degree of cervicobrachialgia and may indicate an increase in the local inflammatory response in cervicobrachial syndrome. 

Author Biographies

Jovan Ilić, Department of Neurosurgery, University Clinical Center of Niš, Niš, Serbia

https://orcid.org/

0000-0003-0730-1060
Aleksandar Kostić, Department of Neurosurgery, University Clinical Center of Niš, Niš, Serbia

1Department of Neurosurgery, University Clinical Center of Niš, Niš, Serbia

2Faculty of Medicine, University of Niš, Niš, Serbia

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Published
2024/10/31
Section
Original article