Role of biochemical markers in the monitoring of COVID-19 patients

  • Pablo Letelier Precision Health Research Laboratory, Departamento de Procesos Diagnósticos y Evaluación, Facultad Ciencias de la Salud, Universidad Católica de Temuco
  • Nicole Encina Precision Health Research Laboratory, Departamento de Procesos Diagnósticos y Evaluación, Facultad de Ciencias de la Salud, Universidad Católica de Temuco, Chile.
  • Pablo Morales Precision Health Research Laboratory, Departamento de Procesos Diagnósticos y Evaluación, Facultad de Ciencias de la Salud, Universidad Católica de Temuco, Chile.
  • Alejandra Riffo Precision Health Research Laboratory, Departamento de Procesos Diagnósticos y Evaluación, Facultad de Ciencias de la Salud, Universidad Católica de Temuco, Chile.
  • Halett Silva Precision Health Research Laboratory, Departamento de Procesos Diagnósticos y Evaluación, Facultad de Ciencias de la Salud, Universidad Católica de Temuco, Chile.
  • Ismael Riquelme Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Chile
  • Neftalí Guzmán Precision Health Research Laboratory, Departamento de Procesos Diagnósticos y Evaluación, Facultad de Ciencias de la Salud, Universidad Católica de Temuco, Chile.
DOI: https://doi.org/10.5937/jomb0-29341
Keywords: Coronavirus disease; COVID-19; SARS-CoV-2; Laboratory diagnosis; Biomarkers

Abstract


COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which has given rise to a global sanitary emergency. The clinical characteristics of COVID-19 are varied and can range from an asymptomatic infection to a mild to severe pneumonia. Recent studies have shown that different laboratory parameters become altered in these patients, and as such are useful as biomarkers to assess the progression of the disease and categorize patients that may present a severe and/or fatal clinical condition.

This review analyzes biochemical and immunological markers that become altered in COVID-19 patients and their impact on different organs at a hepatic, cardiac, renal and pancreatic level, as well as markers of inflammation, analyzing their implications in the evolution of the disease.

Published
2020/12/09
Issue
Vol. 40 No. 2 (2021): Journal of Medical Biochemistry
Section
Review article

Copyright (c) 2020 Pablo Letelier, Nicole Encina, Pablo Morales, Alejandra Riffo, Halett Silva, Ismael Riquelme , Neftalí Guzmán

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