the The Improvement of Fbg, Ang-1, VEGF, BDNF in Postoperative Patients with Brain Trauma Through Target Task Oriented Phrase Training
Fbg, Ang-1, VEGF, BDNF in Postoperative Patients
Abstract
Objective:It aims to explore the effect of target task oriented phase training on fibrinogen (Fbg), angiopoietin (Ang-1), vascular endothelial growth factor (VEGF), serum brain derived neurotrophic factor (BDNF) and quality of life in postoperative patients with brain trauma. Methods:142 patients with brain trauma who were operated in neurosurgery of our hospital from March 2020 to March 2023 are chosen and separated into two groups by random number table. The control group (n=71) receive routine postoperative training, and the experimental group (n=71) receive target task oriented training based on the control group, and the serum cell levels of nursing for 3, 7 and 14 days are compared. Improvement of limb function and quality of life after 2, 4, and 6 weeks of nursing care is observed. Results: Before nursing, the comparison in serum factor levels, limb function scores, and quality of life scores between the two groups was with P>0.05; After 3, 7, and 14 days of nursing, the Fbg of the control group was higher than that of the experimental group; The Ang-1, VEGF, and BDNF levels in the experimental group were higher than those in the control group (P<0.05); After 2, 4, and 6 weeks of nursing care, the FMA scores of the upper and lower limbs in the control group were lower than those in the experimental group, with P<0.05; The scores in the physiological, environmental, psychological, and social fields of thecontrol group were lower than those of the experimental group, with P<0.05. Conclusion: The application of target task oriented phase training in patients with brain trauma after surgery can help promote the serum levels of Fbg, Ang-1, VEGF, and BDNF, improve limb function, and enhance quality of life.
References
1. Bujok J, Bobiński R, Dutka M,et al. Open craniocerebral trauma in a patient atwork: A case report[J]. Work. 2022,72(3):989-995.
2. Rong X .Effects of Continuous Nursing Intervention on Postoperative Rehabilitation of Patients with Craniocerebral Trauma[J].Journal of Clinical and Nursing Research, 2022, 6(1):86-90.
3. Güneş Gencer GY, Yilmaz Ö. The effect of trunk training on trunk control, upperextremity, andpulmonary function in children with Duchenne muscular dystrophy: A randomized clinical trial[J]. Clin Rehabil. 2022,36(3):369-378.
4. Naeeni Davarani M, Arian Darestani A, Hassani-Abharian P,et al. RehaCom rehabilitation training improves a wide-range of cognitive functions in multiple sclerosis patients[J]. Appl Neuropsychol Adult. 2022,29(2):262-272.
5. Guo P C , Li N , Zhong H M ,et al.Clinical effectiveness of a pneumatic compression device combined with low-molecular-weight heparin for the prevention of deep vein thrombosis in trauma patients:A single-center retrospective cohort study[J].World Journal of Emergency Medicine, 2022,(003)013:189-195.
6. Langarita R, Armejach A, Setoain J, et al. Compressed Sparse FM-Index: Fast Sequence Alignment Using Large K-Steps[J]. IEEE/ACM Trans Comput Biol Bioinform. 2022,19(1):355-368.
7. [1] Yang G .Progress in Analgesic-Sedative Treatment in Perioperative Period of Hypertensive Intracerebral Hemorrhage[J]. Surgical Science, 2022,(007)013:327-334.
8. West ML, Parrish EM, Green J, et al. Individualized vocational and educational support and training for youth at clinical high risk for psychosis[J]. Early Interv Psychiatry. 2022 ,16(5):492-499.
9. Handelzalts S, Volk M, Zendler JD,et al. Physical Activity Patterns in Frail and Nonfrail Patients With End-Stage Liver Disease[J]. J Clin Exp Hepatol. 2022 ,12(3):887-892.
10. Manavi Roodsari S, Freund S, Zam A,et al. Fabrication and Characterization of a Flexible FBG-Based Shape Sensor Using Single-Mode Fibers. IEEE Trans Biomed Eng. 2022,69(8):2488-2498.
11. Ahmad A, Nawaz MI. Molecular mechanism of VEGF and its role in pathological angiogenesis[J]. J Cell Biochem. 2022,123(12):1938-1965.
12. Ahuja P, Ng CF, Pang BPS,et al. Muscle-generated BDNF (brain derived neurotrophic factor) maintains mitochondrial quality control in female mice[J]. Autophagy. 2022,18(6):1367-1384.
13. Talmor-Barkan Y, Bar N, Shaul AA,et al. Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease[J]. Nat Med. 2022 Feb;28(2):295-302.
14. Koyama S, Ohno Y, Haseda Y,et al. Verification of embedding conditions for FBG sensor into textile product for the development of wearable healthcare sensor[J]. Technol Health Care. 2022,30(4):787-798.
15. De Deus LA, Neves RVP, Corrêa HL,et al. Improving the prognosis of renal patients: The effects of blood flow-restricted resistance training on redox balance and cardiac autonomic function[J]. Exp Physiol. 2021 ,106(4):1099-1109.
16. Castro MCZ, Santos CMD, Lucas RE,et al. Oral motor function in obesity[J]. J Oral Rehabil. 2022 ,49(5):529-534.
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