KOMPARATIVNA ANALIZA DVE METODE PREZERVACIJE POSTEKSTRAKCIONE ALVEOLE PILOT STUDIJA
Ključne reči:
Ključne reči: A-PRF, ksenograft, CBCT, preservacija postekstrakcione alveole, vođena koštana regeneracija.
Sažetak
SAŽETAK
Uvod: Volumetrijske promene rezidualnog alveolarnog grebena počinju nakon ekstrakcije zuba. One su izraženiji u vestibulo-oralnom aspektu nego u koronarno-apikalnom aspektu. U cilju očuvanja volumena tvrdih i mekih tkiva koriščeno je nekoliko vrsta koštanih graftova, koštanih substituenta i biomaterijala. PRF kao autologni krvni derivat je u upotrebi poslednih godina kao samostalni graft material ili u kombinaciji sa drugim graft materijalima.
Cilj: Klinička i radiološka evaluacija dve različite metode prezervacije postekstrakcione alveole.
Materijal I metod: Dve ispitivane grupe sa 10 ispitanika u svakoj sa prezervirane postekstrakcione alveole sa solo-PRF i PRF+ksenograft. Evaluirane su dimenzionalne promene posle 4 i 6 meseci, gustina novoformirane kosti posle 4 meseci i postoperativni morbiditet tokom prvih 7 dana nakon intervencije.
Rezultati: Statističke analize potvrđuju manju koštanu resorpciju u PRF+ksenograft test grupu u poređenju sa PRF grupom. Bolja gustina novoformirane kosti u PRF+ ksenograft grupe, kao I bolji odnos gustine kosti u alveoli naspram gustine u periapikalnoj regiji. Smanjen postoperativni morbiditet u obe grupe.
Zaključak: Preporuka za primenu PRF-a kao adjuvant sa drugih graftova ili substituenta, i kao samostalni graft material.
Reference
1. Araújo MG, Silva CO, Misawa M, Sukekava F. Alveolar socket healing: what can we learn? Periodontol 2000. 2015 Jun;68(1):122-34. doi: 10.1111/prd.12082. PMID: 25867983.
2. Araújo MG, Lindhe J. Dimensional ridge alterations following tooth extraction. An experimental study in the dog. J Clin Periodontol. 2005 Feb;32(2):212-8. doi: 10.1111/j.1600-051X.2005.00642.x. PMID: 15691354.
3. Schropp L, Wenzel A, Kostopoulos L, Karring T. Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. Int J Periodontics Restorative Dent. 2003 Aug;23(4):313-23. PMID: 12956475
4. McAllister BS, Haghighat K. Bone augmentation techniques. J Periodontol. 2007 Mar;78(3):377-96. doi: 10.1902/jop.2007.060048. PMID: 17335361.
5. Hämmerle CH, Araújo MG, Simion M; Osteology Consensus Group 2011. Evidence-based knowledge on the biology and treatment of extraction sockets. Clin Oral Implants Res. 2012 Feb;23 Suppl 5:80-2. doi: 10.1111/j.1600-0501.2011.02370.x. Erratum in: Clin Oral Implants Res. 2012 May;23(5):641. PMID: 22211307.
6. Miron R J, Hedbom N, Saulacic Y et al. Osteogenic Potential of Autogenous Bone Grafts Harvested with Four Different Surgical Techniques. J Dent Res 2011 90: 1428
7. Choukroun J, Adda F, Schoeffler C, Vervelle A. The PRF: an opportunity in implantology. Implantodontie. 2001;42:55–62.
8. Marx RE. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg. 2004;62:489–496
9. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Mar;101(3):e45-50. doi: 10.1016/j.tripleo.2005.07.009. Epub 2006 Jan 10. PMID: 16504850.
10. Al-Hamed FS, Mahri M, Al-Waeli H, Torres J, Badran Z and Tamimi F (2019) Regenerative Effect of Platelet Concentrates in Oral and Craniofacial Regeneration. Front. Cardiovasc. Med. 6:126. doi: 10.3389/fcvm.2019.00126
11. Dolati S, Yousefi M, Pishgahi A, Nourbakhsh S, Pourabbas B, Shakouri SK. Prospects for the application of growth factors in wound healing. Growth Factors. 2020 Jan;38(1):25-34. doi: 10.1080/08977194.2020.1820499. Epub 2020 Nov 5. PMID: 33148072.
12. Baca-Gonzalez L, Serrano Zamora R, Rancan L, González Fernández-Tresguerres F, Fernández-Tresguerres I, López-Pintor RM, López-Quiles J, Leco I, Torres J. Plasma rich in growth factors (PRGF) and leukocyte-platelet rich fibrin (L-PRF): comparative release of growth factors and biological effect on osteoblasts. Int J Implant Dent. 2022 Oct 3;8(1):39. doi: 10.1186/s40729-022-00440-4. PMID: 36184700; PMCID: PMC9527267.
13. Baca-Gonzalez L, Serrano Zamora R, Rancan L, González Fernández-Tresguerres F, Fernández-Tresguerres I, López-Pintor RM, López-Quiles J, Leco I, Torres J. Plasma rich in growth factors (PRGF) and leukocyte-platelet rich fibrin (L-PRF): comparative release of growth factors and biological effect on osteoblasts. Int J Implant Dent. 2022 Oct 3;8(1):39. doi: 10.1186/s40729-022-00440-4. PMID: 36184700; PMCID: PMC9527267.
14. Pitzurra L, Jansen IDC, de Vries TJ, Hoogenkamp MA, Loos BG. Effects of L-PRF and A-PRF+ on periodontal fibroblasts in in vitro wound healing experiments. J Periodontal Res. 2020 Apr;55(2):287-295. doi: 10.1111/jre.12714. Epub 2019 Nov 28. PMID: 31782171; PMCID: PMC7154757.
15. Nguyen M, Nguyen TT, Tran HLB, Tran DN, Ngo LTQ, Huynh NC. Effects of advanced platelet-rich fibrin combined with xenogenic bone on human periodontal ligament stem cells. Clin Exp Dent Res. 2022 Aug;8(4):875-882. doi: 10.1002/cre2.563. Epub 2022 Mar 26. PMID: 35338771; PMCID: PMC9382045.
16. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part III: leucocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Mar;101(3):e51-5. doi: 10.1016/j.tripleo.2005.07.010. PMID: 16504851.
17. Miron RJ, Zhang Y. Autologous liquid platelet rich fibrin: A novel drug delivery system. Acta Biomater. 2018 Jul 15;75:35-51. doi: 10.1016/j.actbio.2018.05.021. Epub 2018 May 15. PMID: 29772345.
18. Misch C.E. Density of bone: effect on treatment plans, surgical approach, and healing, and progressive loading. Int J Oral Implantol. 1990;6:23–31
19. Kollati P, Koneru S, Dwarakanath CD, Gottumukkala SNVS. Effectiveness of naturally derived bovine hydroxyapatite (Cerabone™) combined with platelet-rich fibrin matrix in socket preservation: A randomized controlled clinical trial. J Indian Soc Periodontol. 2019 Mar-Apr;23(2):145-151. doi: 10.4103/jisp.jisp_400_18. PMID: 30983786; PMCID: PMC6434722.
20. Yewale M, Bhat S, Kamath A, Tamrakar A, Patil V, Algal AS. Advanced platelet-rich fibrin plus and osseous bone graft for socket preservation and ridge augmentation - A randomized control clinical trial. J Oral Biol Craniofac Res. 2021 Apr-Jun;11(2):225-233. doi: 10.1016/j.jobcr.2021.01.016. Epub 2021 Feb 3. PMID: 33665072; PMCID: PMC7900600.
21. Jambhekar S, Kernen F, Bidra AS. Clinical and histologic outcomes of socket grafting after flapless tooth extraction: a systematic review of randomized controlled clinical trials. J Prosthet Dent. 2015 May 1;113(5):371–382.
22. Castro AB, Van Dessel J, Temmerman A, Jacobs R, Quirynen M. Effect of different platelet-rich fibrin matrices for ridge preservation in multiple tooth extractions: A split-mouth randomized controlled clinical trial. J Clin Periodontol. 2021 Jul;48(7):984-995. doi: 10.1111/jcpe.13463. Epub 2021 Apr 18. PMID: 33847018.
2. Araújo MG, Lindhe J. Dimensional ridge alterations following tooth extraction. An experimental study in the dog. J Clin Periodontol. 2005 Feb;32(2):212-8. doi: 10.1111/j.1600-051X.2005.00642.x. PMID: 15691354.
3. Schropp L, Wenzel A, Kostopoulos L, Karring T. Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. Int J Periodontics Restorative Dent. 2003 Aug;23(4):313-23. PMID: 12956475
4. McAllister BS, Haghighat K. Bone augmentation techniques. J Periodontol. 2007 Mar;78(3):377-96. doi: 10.1902/jop.2007.060048. PMID: 17335361.
5. Hämmerle CH, Araújo MG, Simion M; Osteology Consensus Group 2011. Evidence-based knowledge on the biology and treatment of extraction sockets. Clin Oral Implants Res. 2012 Feb;23 Suppl 5:80-2. doi: 10.1111/j.1600-0501.2011.02370.x. Erratum in: Clin Oral Implants Res. 2012 May;23(5):641. PMID: 22211307.
6. Miron R J, Hedbom N, Saulacic Y et al. Osteogenic Potential of Autogenous Bone Grafts Harvested with Four Different Surgical Techniques. J Dent Res 2011 90: 1428
7. Choukroun J, Adda F, Schoeffler C, Vervelle A. The PRF: an opportunity in implantology. Implantodontie. 2001;42:55–62.
8. Marx RE. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg. 2004;62:489–496
9. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Mar;101(3):e45-50. doi: 10.1016/j.tripleo.2005.07.009. Epub 2006 Jan 10. PMID: 16504850.
10. Al-Hamed FS, Mahri M, Al-Waeli H, Torres J, Badran Z and Tamimi F (2019) Regenerative Effect of Platelet Concentrates in Oral and Craniofacial Regeneration. Front. Cardiovasc. Med. 6:126. doi: 10.3389/fcvm.2019.00126
11. Dolati S, Yousefi M, Pishgahi A, Nourbakhsh S, Pourabbas B, Shakouri SK. Prospects for the application of growth factors in wound healing. Growth Factors. 2020 Jan;38(1):25-34. doi: 10.1080/08977194.2020.1820499. Epub 2020 Nov 5. PMID: 33148072.
12. Baca-Gonzalez L, Serrano Zamora R, Rancan L, González Fernández-Tresguerres F, Fernández-Tresguerres I, López-Pintor RM, López-Quiles J, Leco I, Torres J. Plasma rich in growth factors (PRGF) and leukocyte-platelet rich fibrin (L-PRF): comparative release of growth factors and biological effect on osteoblasts. Int J Implant Dent. 2022 Oct 3;8(1):39. doi: 10.1186/s40729-022-00440-4. PMID: 36184700; PMCID: PMC9527267.
13. Baca-Gonzalez L, Serrano Zamora R, Rancan L, González Fernández-Tresguerres F, Fernández-Tresguerres I, López-Pintor RM, López-Quiles J, Leco I, Torres J. Plasma rich in growth factors (PRGF) and leukocyte-platelet rich fibrin (L-PRF): comparative release of growth factors and biological effect on osteoblasts. Int J Implant Dent. 2022 Oct 3;8(1):39. doi: 10.1186/s40729-022-00440-4. PMID: 36184700; PMCID: PMC9527267.
14. Pitzurra L, Jansen IDC, de Vries TJ, Hoogenkamp MA, Loos BG. Effects of L-PRF and A-PRF+ on periodontal fibroblasts in in vitro wound healing experiments. J Periodontal Res. 2020 Apr;55(2):287-295. doi: 10.1111/jre.12714. Epub 2019 Nov 28. PMID: 31782171; PMCID: PMC7154757.
15. Nguyen M, Nguyen TT, Tran HLB, Tran DN, Ngo LTQ, Huynh NC. Effects of advanced platelet-rich fibrin combined with xenogenic bone on human periodontal ligament stem cells. Clin Exp Dent Res. 2022 Aug;8(4):875-882. doi: 10.1002/cre2.563. Epub 2022 Mar 26. PMID: 35338771; PMCID: PMC9382045.
16. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part III: leucocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Mar;101(3):e51-5. doi: 10.1016/j.tripleo.2005.07.010. PMID: 16504851.
17. Miron RJ, Zhang Y. Autologous liquid platelet rich fibrin: A novel drug delivery system. Acta Biomater. 2018 Jul 15;75:35-51. doi: 10.1016/j.actbio.2018.05.021. Epub 2018 May 15. PMID: 29772345.
18. Misch C.E. Density of bone: effect on treatment plans, surgical approach, and healing, and progressive loading. Int J Oral Implantol. 1990;6:23–31
19. Kollati P, Koneru S, Dwarakanath CD, Gottumukkala SNVS. Effectiveness of naturally derived bovine hydroxyapatite (Cerabone™) combined with platelet-rich fibrin matrix in socket preservation: A randomized controlled clinical trial. J Indian Soc Periodontol. 2019 Mar-Apr;23(2):145-151. doi: 10.4103/jisp.jisp_400_18. PMID: 30983786; PMCID: PMC6434722.
20. Yewale M, Bhat S, Kamath A, Tamrakar A, Patil V, Algal AS. Advanced platelet-rich fibrin plus and osseous bone graft for socket preservation and ridge augmentation - A randomized control clinical trial. J Oral Biol Craniofac Res. 2021 Apr-Jun;11(2):225-233. doi: 10.1016/j.jobcr.2021.01.016. Epub 2021 Feb 3. PMID: 33665072; PMCID: PMC7900600.
21. Jambhekar S, Kernen F, Bidra AS. Clinical and histologic outcomes of socket grafting after flapless tooth extraction: a systematic review of randomized controlled clinical trials. J Prosthet Dent. 2015 May 1;113(5):371–382.
22. Castro AB, Van Dessel J, Temmerman A, Jacobs R, Quirynen M. Effect of different platelet-rich fibrin matrices for ridge preservation in multiple tooth extractions: A split-mouth randomized controlled clinical trial. J Clin Periodontol. 2021 Jul;48(7):984-995. doi: 10.1111/jcpe.13463. Epub 2021 Apr 18. PMID: 33847018.
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