Down syndrome incidence during 2007-2012 on Gynaecology and obstrtrics clinic Clinical center Kragujevac
Abstract
During four year period, between January 2007 and December 2011, 8 cases of Down syndrome were diagnosed by amniocentesis of 1208 amnions, which results us incidence of 1 in 151 amnions, also we had 15 cases of liveborn children with Down syndrome in 10822 liveborn babies, which makes an incidence of 1 in 721 liveborns.
1070 pregnancies were with mothers older then 35 years at the time of labor and 5 of 15 live born babies with Down syndrome are from mothers in this group. Also, 9464 pregnancies were with mothers of age 18-35 years and in this group we have 10 cases of Down syndrome. Only 9,99% of all mothers were older then 35 years, and they participated in 33.3% of all Down syndrome. Young mothers had 18-35 years we have 88.3% of all mothers and they participated with only 66,7% children with Down syndrome.
We had 8 fetuses with Down syndrome, all diagnosed with trisomy 21, all were aborted by choice of parents and Ethical committee of Clinical Center Kragujevac.