Adult-Onset Still’s Disease in Clinical Practice of Infectious Diseases: A Case Report
Keywords:
adult onset Still’s disease, fever, rash, arthritis.
Abstract
Adult-onset Still's disease is a rare autoimmune disorder accompanied by a triad of fever, exanthema, and arthralgia. In addition to this dominant presentation, it has a wide spectrum of clinical symptoms, with extensive involvement of multiple organs. Because of this diagnostic of adult-onset Still's disease remains one of exclusion and fulfilling sets of diagnostic criteria
We report on the case of a 20-year-old female who was initially treated for a suspected allergic reaction to a drug and then referred to an infectious disease specialist as Fever of unknown origin accompanied with rash.
References
1. Efthimiou P, Kontzias A, Hur P, Rodha K, Ramakrishna GS, Nakasato P. Adult-onset Still’s disease in focus: Clinical manifestations, diagnosis, treatment, and unmet needs in the era of targeted therapies. Semin Arthritis Rheum [Internet]. 2021;51(4):858–74. Available from: https://doi.org/10.1016/j.semarthrit.2021.06.004
2. Imboden JB, Hellmann DB, Stone JA. Current Diagnosis & Treatment in Rheumatology, Fourth Edition. 2020.
3. Ma Y, Meng J, Jia J et al. Current and emerging biological therapy in adult-onset Still’s disease. Rheumatology (Oxford) [Internet]. 2021 Sep 1 [cited 2023 Nov 21];60(9):3986. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410009/
4. Mehta B, Efthimiou P. Ferritin in Adult-Onset Still’s Disease: Just a Useful Innocent Bystander? Int J Inflam [Internet]. 2012 [cited 2023 Dec 17];2012. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321299/
5. Gerfaud-Valentin M, Jamilloux Y, Iwaz J, Sève P. Adult-onset Still’s disease. Autoimmun Rev. 2014 Jul 1;13(7):708–22.
6. Kim BJ, Kim SY, Kim GM. Adult onset Still’s disesae: A case report. Korean J Dermatology. 2009;47(10):1203–5.
7. Agha-Abbaslou M, Bensaci AM, Dike O, Poznansky MC, Hyat A. Adult-onset still’s disease: Still a serious health problem (a case report and literature review). Am J Case Rep. 2017;18:119–24.
8. Zhu G, Liu G, Liu Y, Xie Q, Shi G. Liver abnormalities in adult onset still’s disease: A retrospective study of 77 chinese patients. J Clin Rheumatol [Internet]. 2009 Sep [cited 2023 Dec 17];15(6):284–8. Available from: https://journals.lww.com/jclinrheum/fulltext/2009/09000/liver_abnormalities_in_adult_onset_still_s.5.aspx
9. Antoniou KM, Margaritopoulos GA, Giannarakis I et al. Adult onset still’s disease: A case report with a rare clinical manifestation and pathophysiological correlations. Case Rep Med. 2013;2013.
10. Giampietro C, Ridene M, Lequerre T et al. Anakinra in adult-onset still’s disease: Long-term treatment in patients resistant to conventional therapy. Arthritis Care Res. 2013 May;65(5):822–6.
2. Imboden JB, Hellmann DB, Stone JA. Current Diagnosis & Treatment in Rheumatology, Fourth Edition. 2020.
3. Ma Y, Meng J, Jia J et al. Current and emerging biological therapy in adult-onset Still’s disease. Rheumatology (Oxford) [Internet]. 2021 Sep 1 [cited 2023 Nov 21];60(9):3986. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410009/
4. Mehta B, Efthimiou P. Ferritin in Adult-Onset Still’s Disease: Just a Useful Innocent Bystander? Int J Inflam [Internet]. 2012 [cited 2023 Dec 17];2012. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321299/
5. Gerfaud-Valentin M, Jamilloux Y, Iwaz J, Sève P. Adult-onset Still’s disease. Autoimmun Rev. 2014 Jul 1;13(7):708–22.
6. Kim BJ, Kim SY, Kim GM. Adult onset Still’s disesae: A case report. Korean J Dermatology. 2009;47(10):1203–5.
7. Agha-Abbaslou M, Bensaci AM, Dike O, Poznansky MC, Hyat A. Adult-onset still’s disease: Still a serious health problem (a case report and literature review). Am J Case Rep. 2017;18:119–24.
8. Zhu G, Liu G, Liu Y, Xie Q, Shi G. Liver abnormalities in adult onset still’s disease: A retrospective study of 77 chinese patients. J Clin Rheumatol [Internet]. 2009 Sep [cited 2023 Dec 17];15(6):284–8. Available from: https://journals.lww.com/jclinrheum/fulltext/2009/09000/liver_abnormalities_in_adult_onset_still_s.5.aspx
9. Antoniou KM, Margaritopoulos GA, Giannarakis I et al. Adult onset still’s disease: A case report with a rare clinical manifestation and pathophysiological correlations. Case Rep Med. 2013;2013.
10. Giampietro C, Ridene M, Lequerre T et al. Anakinra in adult-onset still’s disease: Long-term treatment in patients resistant to conventional therapy. Arthritis Care Res. 2013 May;65(5):822–6.