CELIJAČNA BOLEST KOD DECE

Zoran Lekovic; Vladimir Radlović; Marija Mladenović; Siniša Dučić; Bojan Bukva; Petar Rosić; Nedeljko Radlović

doi:10.5937/medi56-43306

Zoran Lekovic University of Belgrade, Faculty of Medicine https://orcid.org/0000-0002-9927-0881
Dr. Vladimir Radlović University Children’s Hospital, 10 Tiršova St, Belgrade, Serbia;
Marija Mladenović University „Singidunum“, Faculty of Health, Legal and Business Studies, Valjevo, Serbia
Dr. Siniša Dučić University Children’s Hospital, 10 Tiršova St, Belgrade, Serbia;
Bojan Bukva University Children’s Hospital, 10 Tiršova St, Belgrade, Serbia;
Petar Rosić University of Belgrade Faculty of Medicine, Dr Subotića 8, Belgrade, Serbia
Nedeljko Radlović Academy of Medical Sciences of the Serbian Medical Society, Serbia;

DOI: https://doi.org/10.5937/medi56-43306

Keywords: celiac disease, children, clinical forms, diagnostics, therapy

Abstract

Celiac disease is a multisystemic autoimmune disease induced by gluten in wheat, rye and barley. It is characterized by polygenic predisposition, high prevalence in members of the white population (1%), especially in close relatives (5-15%), very heterogeneous expression and frequent association with other autoimmune diseases (3-10%), as well as selective deficiency of IgA and Down, Turner and Williams syndromes. The basis of the disease and the key finding in its diagnostics is symptomatic or asymptomatic inflammation of the small intestinal mucosa which resolves by gluten-free diet. Accordingly, the basis of the treatment involves an elimination diet, so that the disorder, if timely recognized and adequately treated, also characterizes an excellent prognosis.

CELIAC DISEASE IN CHILDREN

Abstract