RISK FACTORS FOR NOSOCOMIAL INFECTIONS IN MECHANICALLY VENTILATED NEONATES АТ INTENSIVE CARE UNIT

Zorana Djordjević; Valentina Opančina; Marija Živković Radojević; Zoran Protrka; Dragana Savić; Gordana Rajković; Dragana Ristić; Slobodan Janković

doi:10.5937/racter10-18728

Zorana Djordjević Epidemiology Department, Clinical Center, Kragujevac, Serbia
Valentina Opančina University of Kragujevac, Serbia, Faculty of Medical Sciences, Department of Radiology
Marija Živković Radojević Department for Oncology, Clinical Center, Kragujevac, Serbia
Zoran Protrka University of Kragujevac, Serbia, Faculty of Medical Sciences, Department of Gynecology and Obstetrics
Dragana Savić University of Kragujevac, Serbia, Faculty of Medical Sciences, Department of Pediatrics
Gordana Rajković Department of Pediatrics, Clinical Center Kragujevac
Dragana Ristić Department of Pediatrics, Clinical Center Kragujevac
Slobodan Janković University of Kragujevac, Serbia, Faculty of Medical Sciences, Department of Pharmacology and Toxicology

DOI: https://doi.org/10.5937/racter10-18728

Keywords: nosocomial infections, mechanic ventilation, neonates, intensive care unit,

Abstract

Introduction and aim. Neonatal nosocomial infection (Nis) is defined as the occurrence of infection 48 hours after birth which is caused by a nosocomial pathogen. Newborns admitted to neonatal intensive care units (NICU) are at increased risk for developing Nis. The aim of our study was to describe risk factors for Nis at mechanically ventilated (MV) neonates in a NICU.

Materials and methods. The study was designed as a case/control study nested in the prospective cohort study. The study population consisted of the neonates supported by MV and admitted at the NICU. Risk factors were identified and their influence quantified by logistic regression.

Results. Our study showed that MV neonates in NICU, who were longer carrying peripheral venous catheter (PVC) and spend more time in a hospital, were more likely to get NIs (OR=1.091, CI=1.035-1.151). The neonates having an infection on admittance were less likely to acquire NIs.

Conclusions. Development of NIs in MV neonates could be prevented by education of hospital staff and shortening of hospitalization. The rate of nosocomial infections will drop if exposure of newborns to pathogens from the hospital environment and to invasive devices is decreased.

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