METASTASIS OF SUBMANDIBULAR ADENOID CYSTIC CARCINOMA TO THE FEMUR BONE CAUSING PATHOLOGICAL FRACTURE: A CASE REPORT

  • Mustafa Onur Karaca Department of Orthopedics and Traumatology, Faculty of Medicine, Ankara University
  • Kamil Balaban Department of Orthopedics and Traumatology, Faculty of Medicine, Ankara University, Turkey
  • Hüseyin Yusuf Yıldız Department of Orthopedics and Traumatology, Faculty of Medicine, Ankara University, Turkey
DOI: https://doi.org/10.5937/sanamed0-40661
Keywords: Adenoid cystic carcinoma, submandibular gland, bone metastasis, pathological fracture, femur

Abstract


Introduction: Adenoid cystic carcinoma (ACC) is a rare head and neck malignancy and is likely to be diagnosed in the major salivary glands. It's also known for its slow clinical course and prolonged survival unless no distant metastasis occurs. Even after a long period from the detection of the primary tumor, metastasis to the lung, brain, liver, and bone has a tendency to occur.

Case presentation: We report a 53-year-old man who presented with a pathological femur fracture thirteen years after the presentation of submandibular ACC. Our patient reported an improved patient-reported outcome after undergoing resection hemiarthroplasty for his bone metastasis.

 

Conclusion: We tried to accentuate the importance of periodical visits for the probability of distant metastasis and the work-up if it's necessary in such a rare case. It should be kept in mind that proper management of bone metastasis may lead to improvements in the quality of life.

 

References

1.        Coca-Pelaz A, Rodrigo JP, Bradley PJ, Vander Poorten V, Triantafyllou A, Hunt JL, et al. Adenoid cystic carcinoma of the head and neck - An update. Oral Oncol. 2015;51(7):652-61. doi: 10.1016/j.oraloncology.2015.04.005.

2.        Bradley PJ. Adenoid cystic carcinoma evaluation and management : progress with optimism! CurrOpinOtolaryngol Head Neck Surg. 2017;25(2):147-53. doi: 10.1097/MOO.0000000000000347.

3.        Kokemueller H, Eckardt A, Brachvogel P, Hausamen JE. Adenoid cystic carcinoma of the head and neck - A 20 years experience. Int J Oral Maxillofac Surg. 2004;33(1):25-31. doi: 10.1054/ijom.2003.0448.

4.        Zhang J, Sun Y, Li Z, Feng H. Metastasis of submandibular gland carcinoma to the toe bone: a case report. Br J Oral Maxillofac Surg. 2019;57(4):368-70. doi: 10.1016/j.bjoms.2019.03.011.

5.     Thariat J, Fournier LS, Badoual C, Marcy PY, Housset M. Aggressive Adenoid cystic carcinoma with asymptomatic spinal cord compression revealed by a “Curtain sign.” J Radiol Case Rep. 2008;2(1) :12-5. doi: 10.3941/jrcr.v2i1.3. 

6.        Weitzner S. Adenoid cystic carcinoma of submaxillary gland metastatic to the great toe. Am Surg. 1975;41(10):655-8.

7.        Marshall RA, Mandell JC, Weaver MJ, Ferrone M, Sodickson A, Khurana B. Imaging features and management of stress, atypical, and pathologic fractures. RadioGraphics. 2018;38(7):2173-92. doi: 10.1148/rg.2018180073.

8.        Anract P, Biau D, Boudou-Rouquette P. Metastatic fractures of long limb bones. Orthop Traumatol Surg Res. 2017;103(1):S41-S51. doi: 10.1016/j.otsr.2016.11.001.

 

 

Published
2022/12/03
Issue
Vol. 17 No. 3 (2022): SANAMED
Section
Case report

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