ABH SECRETOR STATUS AMONG THE UNIVERSITY OF CALABAR UNDERGRADUATES, NIGERIA
Abstract
Introduction: Secretor status is a critical component of human biology that depends on specific glycoproteins in body fluids and secretions. Its importance lies in its significant impact on health and disease, making it a compelling subject for medical research. This study aimed to determine the prevalence and understanding of secretor status among undergraduates at the University of Calabar, Nigeria. The findings could revolutionize our understanding of secretor status and open new research opportunities.
Materials and Methods: The study used across-sectional approach, analyzing blood samples from 100 undergraduate students using the adsorption-inhibition method. Most participants were single (94.0%), and the majority were 100-level students (51.0%). 48 students were in the 21 to 28-year range, while 6.0% were 30 or older.
Results: The findings of this study are significant, revealing that a substantial proportion of the participants were secretors, 82(82.0%), while 18(18.0%) were non-secretors.Interestingly, most participants (83.0%) were unaware of their secretor status, indicating a potential knowledge gap. Blood group O had the highest number of secretors, 58(96.7%), followed by blood group A 11 (55.0%), blood group B 7(63.6%), and the minor blood group AB 6(66.7%). The most prevalent ethnic group was found among the Efiks (18.1%) followed by Yakurr (16.6%) and the least the Ijaws (3.8%).
Conclusion: This study underscores the importance of public education and awareness regarding secretor status and its impact on health and disease
References
Etura JE, Effiong UI, Asemota EA, Okoroiwu HU. ABO phenotypes, Rhesus and Kell 2 antigens of blood donors attending University of Calabar Teaching Hospital. The Nig Health J. 2023; 23(4):1010-6.
Harmening DM. Modern Blood Banking & Transfusion Practices. https://books.google.com.ng/books. 2018; Retrieved January 18, 2022, from https://books.google.com.ng/books?id=vxyDDwAAQBAJ&redir_esc=y
Marionnea S, Cailleau-Thomas A, Rocher J, Le Moullac-Vaidye B, Ruvoën N, Clément M, et al. ABH and Lewis histo-blood group antigens, a model for the meaning of oligosaccharide diversity in the face of a changing world. Biochimie, 2001; 83(7): 565-73.
Dean L. Blood groups and red cell antigens (Vol. 2). Bethesda: National Center for Biotechnology Information. 2005.
Harmening DM, Forneris G, TubbyBJ. The ABO blood group system. Modern blood banking and transfusion practices. 6th ed. Philadelphia: FA Davis Company Publications, 2012; 119-45.
Rydell GE, Kindberg E, Larson G, Svensson L. Susceptibility to winter vomiting disease: a sweet matter. Rev MedVirol, 2011; 21(6): 370-382.
Bakhtiari S, Yadegari Z, Kaviyani M, Namazi Z, Bakhshi M. Secretor status of ABO antigens in saliva of a defined group of Iranian patients with Pemphigus Vulgaris: a Case-Control study. Scientifica (Cairo). 2020;2020:2950856. doi: 10.1155/2020/2950856.
Emeribe AO, Igweagu CA, Osim EE. (1992). ABH secretor status in the saliva of Calabar Municipality residents. East Afr Med J. 1992; 69(1): 27-30. doi: 10.1055/s-0041-1723083.
Jaff MS. Higher frequency of secretor phenotype in O blood group–its benefits in prevention and/or treatment of some diseases. Int J Nanomedicine. 201; 5:901-5. doi: 10.2147/IJN.S13980.
Tejasvi MA, Bukkya JL, Rao PR, Bhayya H. Evaluation of the secretor status of ABO blood group antigens in saliva using absorption inhibition method. Global Med Genet. 2021;8(1): 19-23.
Akhter S, Kibria GM, Akhter NR, Habibullah MM, Islam SMK, Zakariah M. ABO and Lewis blood grouping with ABH secretor and non-secretor status: a cross- sectional study in Dhaka. Faridpur Med College J. 2011; 6(1): 3840.
Sherwani SK, Ahmad H, Ahmad T, Hussain T, Akbar S, Zaidi SA, Kazmi S. U.. Status of secretor and non–secretor with respect to ABO blood group system in Young Population in Karachi-Pakistan. World J Med Sci. 2014; 10(1): 22-5.
McGovern DPB, Jones MR, Taylor KD, Marciante K, Yan X, Dubinsky M, et al. Fucosyltransferase 2 (FUT2) non- secretor status is associated with Crohn's disease, Hum Mol Genet. 2010; 19 (17) : 3468–76. doi:10.1093/hmg/ddq248.
Etura J, Andrew K, Akpan U, Jeremiah Z. Haematological variations associated with alcohol consumption in a Nigerian university community.Sanamed.2024;19(2): 171-80. doi: 10.5937/sanamed0-51524.
Apollos V, Jacob R, Jeremiah Z. Performance evaluation of Veri-Q Red haemoglobin meter for point-of-care haemoglobin and packed cell volume estimations. Sanamed. 2024; 19(1): 33–8. doi: 10.5937/sanamed19-48722.
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