NEW DAWN FADES: FROM IMAGING TO QUANTITATIVE IMAGING BIOMARKERS AND BEYOND

  • Miloš A. Lučić 1 Medical Faculty, University of Novi Sad, Serbia 2 Medical Faculty, University of Banja Luka, RS, BiH 3 Diagnostic Imaging Center, Oncology Institute of Vojvodina, Sremska Kamenica/Novi Sad, Serbia

Abstract


In the modern ages of rapid technological and computational advances, development of numerous novel diagnostic imaging techniques have enabled not only visual detection of disease processes, but also provided the tools to achieve quantified functional, structural, dynamic, metabolic, and molecular information. A pathway toward the quantitative imaging by use of quantitative imaging biomarkers analysis has been widely opened, enabling further development of radiomics, radiogenomics, and radioproteinomics analysis in addition, and initiating the dawn of theranostics, eventually bringing the wishful personalized medicine concept closer to reality.

References

Raunig DL, McShane LM, Pennello G, Gatsonis C, Carson PL, Voyvodic JT, et al; QIBA Technical Performance Working Group. Quantitative imaging biomarkers: a review of statistical methods for technical performance assessment. Stat Methods Med Res 2015;24(1):27-67.

Cha S. Update on brain tumor imaging: from anatomy to physiology. AJNR Am J Neuroradiol 2006;27(3):475-87.

Buckler AJ, Paik D, Ouellette M, Danagoulian J, Wernsing G, Suzek BE. A novel knowledge representation framework for the statistical validation of quantitative imaging biomarkers. J Digit Imaging 2013;26(4):614-29.

Radiological Society of North America [Accessed on June 24, 2019]; Quantitative Imaging Biomarkers Alliance. Available at: https://www.rsna.org/en/research/quantitative-imaging-biomarkers-alliance

Rosenkrantz AB, Mendiratta-Lala M, Bartholmai BJ, Ganeshan D, Abramson RG, Burton KR, et al. Clinical utility of quantitative imaging. Acad Radiol 2015;22(1):33-49.

Anderson CJ, Lewis JS. Current status and future challenges for molecular imaging. Philos Trans A Math Phys Eng Sci 2017;375(2107). pii: 20170023. doi: 10.1098/rsta.2017.0023.

Martín Noguerol T, Martínez Barbero JP. Advanced diffusion MRI and biomarkers in the central nervous system: a new approach. Radiologia 2017;59(4):273-85.

Cook GJR, Azad G, Owczarczyk K, Siddique M, Goh V. Challenges and Promises of PET Radiomics. Int J Radiat Oncol Biol Phys 2018;102(4):1083-9.

Lee JW, Lee SM. Radiomics in Oncological PET/CT: Clinical Applications. Nucl Med Mol Imaging 2018;52(3):170-89.

Tofts PS, Collins DJ. Multicentre imaging measurements for oncology and in the brain. Br J Radiol 2011;84(Spec. No. 2):S213-26.

Saadatpour Z, Rezaei A, Ebrahimnejad H, Baghaei B, Bjorklund G, Chartrand M, et al. Imaging techniques: new avenues in cancer gene and cell therapy. Cancer Gene Ther 2017;24(1):1-5.

European Society of Radiology. Medical imaging in personalised medicine: a white paper of the research committee of the European Society of Radiology (ESR). Insights Imaging 2015;6(2):141-55.

Acharya UR, Hagiwara Y, Sudarshan VK, Chan WY, Ng KH. Towards precision medicine: from quantitative imaging to radiomics. J Zhejiang Univ Sci B 2018;19(1):6-24.

Lambin P, Leijenaar RTH, Deist TM, Peerlings J, de Jong EEC, van Timmeren J, Sanduleanu S, et al. Radiomics: the bridge between medical imaging and personalized medicine. Nat Rev Clin Oncol 2017;14(12):749-62.

Gillies RJ, Kinahan PE, Hricak H. Radiomics: Images Are More than Pictures, They Are Data. Radiology 2016 Feb;278(2):563-77.

Lee DY, Li KC. Molecular theranostics: a primer for the imaging professional. AJR Am J Roentgenol 2011;197(2):318-24.

Jones KM, Pollard AC, Pagel MD. Clinical applications of chemical exchange saturation transfer (CEST) MRI. J Magn Reson Imaging. 2018;47(1):11-27. doi: 10.1002/jmri.25838.

Ma D, Gulani V, Seiberlich N, Liu K, Sunshine JL, Duerk JL, Griswold MA. Magnetic resonance fingerprinting. Nature. 2013;495(7440):187-92. doi: 10.1038/nature11971.

Cohen O, Huang S, McMahon MT, Rosen MS, Farrar CT. Rapid and quantitative chemical exchange saturation transfer (CEST) imaging with magnetic resonance fingerprinting (MRF). Magn Reson Med. 2018;80(6):2449-63. doi: 10.1002/mrm.27221.

Published
2019/08/08
Section
Editorial