Evaluation of Nephrolithometric Scoring Systems to Predict Outcomes and Complications of Percutaneous Nephrolithotomy for Staghorn Stone

  • Mehmet Yilmaz bagcilar training and research hospital
  • Gökhan Çil no
Keywords: Kidney stone, Percutaneous nephrolithotomy, Guy's Score, CROES nomogram, S.T.O.N.E. score

Abstract


Background/Aim: Urinary system stone disease develops with a frequency of 1-20 % in the general population. There are various surgical methods and percutaneous nephrolithotomy (PCNL) is a commonly used treatment method, especially in large, staghorn kidney stones. Aim of this study was compare stone nomograms in forecasting operative and complicating parameters subsequent to PCNL in staghorn stones.

Methods: The study analysed 66 patients with staghorn stones who underwent percutaneous nephrolithotomy between 2017 and 2022, retrospectively. The researcher evaluated the Guy, S.T.O.N.E. and CROSS nephrolithotomy scores in patients using non-contrast computed tomography. The Clavien Dindo Classification was used to evaluate the surgical complication.

Results: The mean stone burden, GUY, S.T.O.N.E. and CROES scores were 1114.9 ± 52018 mm²; 3.64 ± 0.48; 10.11 ± 1.2 and 142.9 ± 31.99, respectively. Total stone-free status (SFS) was achieved in 37.9 % of the patients, while the median stone clearance rate was 93.74 (50-100). While no statistical significance was observed between GUY score and SFS, it was observed in S.T.O.N.E. and CROES scores (p = 0.020 and 0.004, respectively). ROC analysis showed that CROES and S.T.O.N.E. scoring systems and the stone burden parameter showed similar accuracy in the estimation of SFS. The results showed that only the S.T.O.N.E. score showed a significant relationship with the presence of complications (p = 0.034).

Conclusion: If the percutaneous nephrolithotomy for staghorn stones in question is, current scoring systems alone couldn't be predictive for postoperative outcomes and degree of complications. Further large scale multicentre prospective studies are needful.

References

1.    Thongprayoon C, Krambeck AE, Rule AD. Determining the true burden of kidney stone disease. Nat Rev Nephrol 2020 Dec;16(12):736-46.

2.    Dave C, Shetty S, Faraj K, Howes DS, Sinert RH, Craig S, et al. Nephrolithiasis treatment & management [Internet]. [Cited: 27-Jun-2015]. Available at: http:// emedicine.medscape.com/article/437096-treatment.

3.    Geraghty RM, Davis NF, Tzelves L, Lombardo R, Yuan C, Thomas K, et al. Best practice in interventional management of urolithiasis: an update from the European Association of Urology Guidelines Panel for Urolithiasis 2022. Eur Urol Focus 2023 Jan;9(1):199-208.

4.    Cracco CM, Scoffone CM. Endoscopic combined intrarenal surgery (ECIRS) - Tips and tricks to improve outcomes: A systematic review. Turk J Urol 2020 Nov;46(Supp. 1):S46-S57.

5.    Yang T, Liu S, Hu J, Wang L, Jiang H. The evaluation of risk factors for postoperative infectious complications after percutaneous nephrolithotomy. Biomed Res Int 2017;2017:4832051. doi: 10.1155/2017/4832051.

6.    Yarimoglu S, Bozkurt IH, Aydogdu O, Yonguc T, Sefik E, Topcu YK, et al. External validation and comparison of the scoring systems (S.T.O.N.E, GUY, CROES, S-ReSC) for predicting percutaneous nephrolithotomy outcomes for staghorn stones: A single center experience with 160 cases. Kaohsiung J Med Sci 2017 Oct;33(10):516-22.

7.    Al Adl AM, Mohey A, Abdel Aal A, Abu-Elnasr HAF, El Karamany T, Noureldin YA. Percutaneous nephrolithotomy outcomes based on S.T.O.N.E., GUY, CROES, and S-ReSC scoring systems: the first prospective study. J Endourol 2020 Dec;34(12):1223-8.

8.    Kumar U, Tomar V, Yadav SS, Priyadarshi S, Vyas N, Agarwal N, et al. STONE score versus Guy's Stone Score - prospective comparative evaluation for success rate and complications in percutaneous nephrolithotomy. Urol Ann 2018;10:76-81.

9.    Ketsuwan C, Kijvikai K, Kongchareonsombat W, Sangkum P, Rongthong S, Leenanupunth C. A comprehensive comparison of Guy’s stone score, CROES nomogram, S.T.O.N.E. nephrolithometry, and the Seoul renal stone complexity scoring system in predicting perioperative outcomes after percutaneous nephrolithotomy. J Med Assoc Thai 2020;103:762-6.

10.  Vicentini FC, Serzedello FR, Thomas K, Marchini GS, Torricelli FCM, Srougi M, et al. What is the quickest scoring system to predict percutaneous nephrolithotomy outcomes? A comparative study among S.T.O.N.E score, guy's stone score and croes nomogram. Int Braz J Urol 2017 Nov-Dec;43(6):1102-9.

11.  de la Rosette JJ, Opondo D, Daels FP, Giusti G, Serrano A, Kandasami SV, et al; CROES PCNL Study Group. Categorisation of complications and validation of the Clavien score for percutaneous nephrolithotomy. Eur Urol 2012 Aug;62(2):246-55.

12.  Tiselius HG, Andersson A. Stone burden in an average Swedish population of stone formers requiring active stone removal: how can the stone size be estimated in the clinical routine? Eur Urol 2003 Mar;43(3):275-81.

13.  Labadie K, Okhunov Z, Akhavein A, Moreira DM, Moreno-Palacios J, Del Junco M, et al. Evaluation and comparison of urolithiasis scoring systems used in percutaneous kidney stone surgery. J Urol 2015 Jan;193(1):154-9.

14.  Lai S, Jiao B, Jiang Z, Liu J, Seery S, Chen X, et al. Comparing different kidney stone scoring systems for predicting percutaneous nephrolithotomy outcomes: A multicenter retrospective cohort study. Int J Surg 2020 Sep; 81:55-60.

15.  Türk C, Petrik A, Sarica K, Seitz C, Skolarikos A, Straub M, et al. EAU guidelines on interventional treatment for urolithiasis. Eur Urol 2016;69:475-82.

16.  Thomas K, Smith NC, Hegarty N, Glass JM. The Guy’s stone score – grading the complexity of percutaneous nephrolithotomy procedures. Urology 2011;78:277–81.

17.  Michel MS, Trojan L, Rassweiler JJ. Complications in percutaneous nephrolithotomy. Eur Urol 2007;51:899-906; discussion 906.

18.  Khan N, Nazim SM, Farhan M, Salam B, Ather MH. Validation of S.T.O.N.E nephrolithometry and Guy's stone score for predicting surgical outcome after percutaneous nephrolithotomy. Urol Ann 2020 Oct-Dec;12(4):324-30.

19.  Kumsar Ş, Aydemir H, Halis F, Köse O, Gökçe A, Adsan O. Value of preoperative stone scoring systems in predicting the results of percutaneous nephrolithotomy. Cent European J Urol 2015;68(3):353-7.

20.  Singla A, Khattar N, Nayyar R, Mehra S, Goel H, Sood R. How practical is the application of percutaneous nephrolithotomy scoring systems? Prospective study comparing Guy's Stone Score, S.T.O.N.E. score and the Clinical Research Office of the Endourological Society (CROES) nomogram. Arab J Urol 2017 Jan 12;15(1):7-16.

21.  Jeong CW, Jung JW, Cha WH, Lee BK, Lee S, Jeong SJ, et al. Seoul National University Renal Stone Complexity Score for predicting stone-free rate after percutaneous nephrolithotomy. PLoS One 2013 Jun 18;8(6):e 65888. doi: 10.1371/journal.pone.0065888.

22.  Mishra S, Sabnis RB, Desai M. Staghorn morphometry: a new tool for clinical classification and prediction model for percutaneous nephrolithotomy monotherapy. J Endourol 2012 Jan;26(1):6-14.

23.  Mishra S, Sabnis RB, Desai MR. Percutaneous nephrolithotomy monotherapy for staghorn: paradigm shift for 'staghorn morphometry' based clinical classification. Curr Opin Urol 2012 Mar;22(2):148-53.

Published
2023/09/20
Section
Original article