Potential of Naringin, Hesperidin and Rutin: Phytochemical and Biological Benefits

Loveleen Kaur; Athrv  Arora; Shifali  Gupta; Sapna  Kumari; Madhukar Garg; Hitesh Chopra

doi:10.5937/scriptamed56-54680

Loveleen Kaur Chitkara University
Athrv Arora Chitkara University
Shifali Gupta Chitkara University
Sapna Kumari Shiva Institute of Pharmacy
Madhukar Garg Chitkara University
Hitesh Chopra Saveetha college of Engineering

DOI: https://doi.org/10.5937/scriptamed56-54680

Keywords: Flavonoids, Cytokines, Signal transduction, Neuroprotective agents, Hesperidine, Rutin, Naringin

Abstract

This review provides an overview of the recent biological and phytochemical advancements of the compounds such as naringin, hesperidin and rutin, which are bioactive flavonoids mainly present in citrus fruits with substantial therapeutic potential. Naringin possesses beneficial properties such as antioxidant, antitumor, antiviral and many more discussed in the article. Studies have indicated that naringin aids in slowing the progression of cancer in different regions of the body. Its anticancer effects are so extensive that it can change how cells interact and transmit signals, decrease the production of specific proteins such as cytokines and growth factors, and also impede the proliferation of cancer cells. Hesperidin has demonstrated notable anticancer and neuroprotective potential. Rutin is widely recognised or known for its venotonic, anti-thrombotic, anti-inflammatory and anticancer properties. This review offers in-depth analysis and details of their constituents and their industrial applications.

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