PERSPECTIVES IN REGENERATION OF ALVEOLAR BONE DEFECTS
Abstract
Bone atrophy of the alveolar process is an important parameter in patients undergoing dental implants. There are several possibilities for preserving the alveolar process, with the autologous bone graft being the gold standard. Other approaches include the use of allografts, xenografts and synthetic bone grafts.
In recent years the use of stem cells has increased in importance. The most commonly type of stem cells exploit and use are mesenchymal stem cell from various sources, included bone marrow, adipose tissue and from dental pulp. Discovery of the induced pluripotent stem cell, as well as the continued research on embryonic stem cell, opens new possibilities in this field.
However, further research is needed to optimize protocols for isolation, differentiation and transplantation of cells with or without appropriate scaffolds and to determine correct clinical and therapeutic implications.
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