EVALUATION OF ABO BLOOD GROUPS DISTRIBUTION IN PATIENTS WITH DIABETES MELLITUS TYPE 2 FROM SERBIA

Ivana Kucevic; Jelena Vasic; Jelena Zvekic Svorcan; Brankica Radisic

doi:10.5937/sjecr14-4214

Ivana Kucevic Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia
Jelena Vasic Department of Public Health "Serbian Railways”, Belgrade, Serbia
Jelena Zvekic Svorcan Medical Faculty, University of Novi Sad, Novi Sad, Serbia
Brankica Radisic Aleksandar MN, Belgrade, Serbia

DOI: https://doi.org/10.5937/sjecr14-4214

Abstract

The aim of our study was to evaluate distribution of ABO blood groups in sample of patients with diagnosed diabetes mellitus type 2 from Serbia. We have evaluated 62 patients from Serbia that were diagnosed with diabetes mellitus type 2. Further ABO blood groups were analyzed: A, B, AB and O. The presence of following risk factors was analyzed: positive family history, elevated triglycerides, increased blood pressure and overweight. Separately male and female genders were evaluated. The most frequent type of blood group in patients with diabetes mellitus type 2 was A blood group, while the least frequent was AB blood group. There is significant increase in distribution of AB blood group in patients with DM type 2 from Serbia compared with frequencies in Serbian population (p<0.05), while for other types of blood groups within ABO system we found non significant distinctions. The highest proportion of evaluated risk factors was noticed for patients with O blood group, while the least proportion for those with A blood group but without statistical significance. Although the sample size of patients is small, the values of our results cold be the initial trends of possible correlation between ABO blood groups and diabetes mellitus type 2 and correlation between ABO blood groups and risk factors in patients with diagnosed diabetes mellitus type 2. Therefore, further studies are needed on larger number of patients.

Author Biographies

Ivana Kucevic, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia

Jelena Vasic, Department of Public Health "Serbian Railways”, Belgrade, Serbia

Jelena Zvekic Svorcan, Medical Faculty, University of Novi Sad, Novi Sad, Serbia

Brankica Radisic, Aleksandar MN, Belgrade, Serbia

References

Chhabra L, Liti B, Kuraganti G, Kaul S, Trivedi N.Challenges in the management of type 2 diabetes mellitus and cardiovascular risk factors in obese subjects: what is the evidence and what are the myths? Int J Endocrinol. 2013;2013:856793.

Boyle JP, Thompson TJ, Gregg EW, Barker LE, Williamson DF. Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence. Population Health Metrics 2010;8:29.

El Ela MH, Azeem AA, Elbastawisy HI, Osman ZM. Population genetic study of diabetes and diabetic retinopathy among Egyptians. Bratisl Lek Listy. 2012;113(10):595-598.

Mandrup-Poulsen T. Type 2 diabetes mellitus: a metabolic autoinflammatory disease. Dermatol Clin. 2013;31(3):495-506.

Bastard JP, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, Capeau J, Feve B. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw. 2006;17(1):4-12.

Jaff MS. Relation between ABO blood groups and Helicobacter pylori infection in symptomatic patients. Clin Exp Gastroenterol. 2011;4:221-226.

Roberts JA. Blood groups and susceptibility to disease: a review. Br J Prev Soc Med. 1957;11:107-125.

Greer JB, Yazer MH, Raval JS, Barmada MM, Brand RE, Whitcomb DC. Significant association between ABO blood group and pancreatic cancer. World J Gastroenterol. 2010;16:5588-5591.

Savic S. PhD thesis. Serbia: School of Medicine, University of Belgrade; 1994. Immunological characteristics of ABO blood group system.

National Blood Pressure Education Program Working group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004;114(2 suppl 4th Report):555-576.

Gong Y, Yang YS, Zhang XM, Su M, Wang J, Han JD, Guo MZ.ABO blood type, diabetes and risk of gastrointestinal cancer in northern China. World J Gastroenterol. 2012;18(6):563-956.

Vioque J, Walker AM. Pancreatic cancer and ABO blood types: a study of cases and controls. Med Clin (Barc) 1991;96:761-764.

Shavakhi A, Hajalikhani M, Minakari M, Norian A, Riahi R, Azarnia M, Liaghat L.The association of non-O blood group and severity of liver fibrosis in patients with chronic hepatitis C infection. J Res Med Sci. 2012;17(5):466-9.

Kamil M, Al-Jamal HA, Yusoff NM. Association of ABO blood groups with diabetes mellitus. Libyan J Med. 2010;5: 10.3402/ljm.v5i0.4847.

Garratty G, Glynn SA, McEntire R; Retrovirus Epidemiology Donor Study. ABO and Rh(D) phenotype frequencies of different racial/ethnic groups in the United States. Transfusion 2004;44(5):703-6.

Nemesure B, Wu SY, Hennis A, Leske MC; Barbados Eye Study Group.Hypertension, type 2 diabetes, and blood groups in a population of African ancestry. Ethn Dis 2006;16(4):822-829.