SPONTANA RUPTURA MATERICE U TRUDNOĆI

  • Radojka Cerović Popović Klinika za ginekologiju i akušerstvo Univerzitetski klinički centar Srbije
  • Radmila Sparić Klinika za ginekologiju i akušerstvo Univerzitetski klinički centar Srbije, Medicinski fakultet Univerzitet u Beogradu https://orcid.org/0000-0003-0515-1951
Ključne reči: ruptura materice, faktor rizika, dijagnoza, tretman

Sažetak


Ruptura materice je životno ugrožavajuća komplikacija trudnoće i povezana je sa visokom učestalošću maternalnog i neonatalnog morbiditeta i mortaliteta. Cilj ovog rada je da prikaže faktore rizika, kliničku sliku, dijagnostičke i terapijske mogućnosti za zbrinjavanje rupture materice. U radu su prikazani podaci iz radova selektovanih pretraživanjem PubMed baze podataka korišćenjem kombinacije ključnih reči: uterine rupture, pregnancy, delivery, risk factors, diagnosis, treatment. 

U razvijenim zemljama ruptura materice je najčešće komplikacija prethodnog carskog reza, a ređe drugih operacija na materici. U zemljama u razvoju se javlja češće i obično je posledica opstrukcije porođaja ili neadekvatne upotrebe medikamenata za indukciju i/ili stimulaciju porođaja. Tipična klinička slika rupture materice podrazumeva pojavu abdominalnog bola i znakova hemoragičnog šoka kod trudnice uz poremećaj rada srca fetusa. Nespecifični simptomi i znaci rupture materice predstavljaju otežavajući faktor za pravovremeno postavljanje dijagnoze. Tretman rupture materice zavisi od obima rupture, starosne dobi, pariteta i opšteg stanja pacijentkinje. Primarni cilj hirurškog zahvata je zaustavljanje krvarenja i hemodinamska stabilizacija pacijentkinje, a podrazumeva histerektomiju ili ušivanje materice. 

Kao posledica sve veće učestalosti porođaja carskim rezom, koji u novije vreme predstavlja najčešći faktor rizika za nastanak rupture materice u trudnoći i porođaju, ruptura materice i dalje predstavlja veoma značajnu komplikaciju trudnoće. Na rupturu materice treba misliti kod trudnica sa prisutnim faktorima rizika, naročito u slučaju pojave nespecifičnog bola u abdomenu i patoloških promena u kardiotokografskom zapisu. U ovakvim situacijama, postavljanje pravovremene dijagnoze i hitno lečenje mogu značajno doprineti povoljnom, kako maternalnom, tako i neonatalnom ishodu. 

Reference

1. Tinelli A. Uterine rupture: up to date. J-DReAM. 2017;1(1):61-74. doi: 10.1285/i25327518v1i1p61

2. Turner MJ. Uterine rupture. Best Pract Res Clin Obstet Gynaecol. 2002;16(1):69-79. doi: 10.1053/beog.2001.0256

3. Tinelli A, Kosmas IP, Carugno JT, Carp H, Malvasi A, Cohen SB, et al. Uterine rupture during pregnancy: The URIDA (uterine rupture international data acquisition) study. Int J Gynaecol Obstet. 2022;157(1):76-84. doi: 10.1002/ijgo.13810.

4. Sparić R, Malvasi A, Kadija S, Babović I, Nejković L, Tinelli A. Cesarean myomectomy trends and controversies: an apprisal. J Matern Fetal Neonatal Med 2017;30(9)1114-23. doi: 10.1080/14767058.2016.1205024.

5. Sparić R, Kadija S, Stefanović A, Spremović Radjenović S, Ladjević Likić I, Popović J, Tinelli A. Cesarean myomectomy in modern obstetrics: more light and less shadows. J Obstet Gynaecol Res 2017;43(5)798-804. doi: 10.1111/jog.1329

6. Berhe Y, Wall LL. Uterine Rupture in Resource-Poor Countries. Obstet Gynecol Surv. 2014;69(11):695–707. doi: 10.1097/OGX.0000000000000123.

7. Tinelli A, Mynbaev OA, Stark M, Sparić R, Kadija S, Gerli S, et al. Spontaneous Uterine Rupture During Pregnancy. In: Non-Obstetrics Surgery During Pregnancy. A Comprehensive Guide. Nezhat CH, Ed. Springer International Publishing AG, Cham, Switzerland, 2019, p. 381-400.

8. Al-Zirqi I, Vangen S. Prelabour uterine rupture: characteristics and outcomes. BJOG. 2020;127(13):1637-44. doi: 10.1111/1471-0528.16363.

9. Abdalla N, Bachanek M, Cendrowski K, Sawicki W. Rupture of Unscarred Uterus: A Rare Cause of Abdominal Pain in Pregnancy. Pain Manage Med. 2015;2(1):106–7. doi:10.4172/jpmme.1000106.

10. Cunningham FG, Leveno KJ, Bloom SL, Dashe JS, Hoffman BL, Casey BM, et al. Obstetrical Hemorrhage. In: Williams Obstetrics, Twenty-Fifth Edition. 2018. p. 755–802.

11. Sturzenegger K, Schäffer L, Zimmermann R, Haslinger C. Risk factors of uterine rupture with a special interest to uterine fundal pressure. J Perinat Med. 2017;45(3):309–13. doi: 10.1515/jpm-2016-0023.

12. Al-Zirqi I, Stray-Pedersen B, Forsén L, Daltveit AK, Vangen S. Uterine rupture: trends over 40 years. BJOG. 2016;123(5):780–7. doi: 10.1111/1471-0528.13394.

13. Chang Y. Uterine rupture over 11 years: A retrospective descriptive study. AustN Z J Obstet Gynaecol. 2020;60(5):709–13. doi: 10.1111/ajo.13133.

14. Vandenberghe G, Bloemenkamp K, Berlage S, Colmorn L, Deneux-Tharaux C, Gissler M, et al. The International Network of Obstetric Survey Systems study of uterine rupture: a descriptive multi-country population-based study. BJOG. 2019;126(3):370–81. doi: 10.1111/1471-0528.1527.

15. Motomura K, Ganchimeg T, Nagata C, Ota E, Vogel JP, Betran AP, et al. Incidence and outcomes of uterine rupture among women with prior caesarean section: WHO Multicountry Survey on Maternal and Newborn Health. Sci Rep. 2017;7(1):1–9. doi: 10.1038/srep44093. doi: 10.1016/j.ajog.2016.10.017.

16. Al-Zirqi I, Daltveit AK, Forsén L, Stray-Pedersen B, Vangen S. Risk factors for complete uterine rupture. Am J Obstet Gynecol. 2017;216(2):165.e1-165.e8.

17. Abdalla N, Reinholz-Jaskolska M, Bachanek M, Cendrowski K, Stanczak R, Sawicki W. Hemoperitoneum in a patient with spontaneous rupture of the posterior wall of an unscarred uterus in the second trimester of pregnancy. BMC Research Notes. 2015;8(1):603. doi: 10.1186/s13104-015-1575-0.

18. Kim HS, Oh SY, Choi SJ, Park HS, Cho GJ, Chung JH, et al. Uterine rupture in pregnancies following myomectomy: A multicenter case series. Obstet Gynecol Sci. 2016;59(6):454–62. doi: 10.5468/ogs.2016.59.6.454.

19. Eshkoli T, Weintraub AY, Baron J, Sheiner E. The significance of a uterine rupture in subsequent births. Arch Gynecol Obstet. 2015;292(4):799–803. doi:10.1007/s00404-015-3715-0.

20. Gambacorti-Passerini Z, Gimovsky AC, Locatelli A, Berghella V. Trial of labor after myomectomy and uterine rupture: a systematic review. Acta Obstet Gynecol Scand. 2016;95(7):724–34. doi: 10.1111/aogs.12920.

21. Sparić R, Mirković L, Ravlić U, Janjić T. Obstetric complications of placenta previa percreta. Vojnosanit Pregl 2014;71(12): 1163-6. doi: 10.2298/VSP1412163S.

22. Igwegbe AO, Eleje GU, Udegbunam OI. Risk factors and perinatal outcome of uterine rupture in a low-resource setting. Niger Med J. 2013;54(6):415-9. doi: 10.4103/0300-1652.126300.

23. Olumide A, Oluwaseun IB, Lawrence AA, Olugbemi OT, Ramon OS. A four-year review of uterine rupture at a secondary health facility in Okitipupa, Southwest Nigeria. J Basic Clin Physiol Pharmacol. 2021 doi: 10.1515/jbcpp-2020-0398.

24. Craver Pryor E, Mertz H, Beaver B, Koontz G, Martinez-Borges A, Smith J, et al. Intrapartum Predictors of Uterine Rupture. Am J Perinatol. 2007;24(5):317–21. doi: 10.1055/s-2007-981433.

25. Cunningham FG, Leveno KJ, Bloom SL, Dashe JS, Hoffman BL, Casey BM, et al. Prior Cesarean Delivery. In: Williams Obstetrics, Twenty-Fifth Edition. 2018. p. 591–603.

26. Langhe R, Shah UF, Alfathil A, Gannon M. Silent uterine rupture in scarred uterus. BMJ Case Reports. 2017:bcr2016218189. doi: 10.1136/bcr-2016-218189.

27. Rottenstreich M, Rotem R, Hirsch A, Farkash R, Rottenstreich A, Samueloff A, et al. Delayed diagnosis of intrapartum uterine rupture – maternal and neonatal consequences. J Matern Fetal Neonatal Med. 2021;34(5):708–13. doi:10.1080/14767058.2019.1613366.

28. Baird EJ. Identification and Management of Obstetric Hemorrhage. Anesthesiol Clin. 2017;35(1):15–34. doi: 10.1016/j.anclin.2016.09.004.

29. Walsh CA, Baxi LV. Rupture of the Primigravid Uterus: A Review of the Literature. Obstet Gynecol Surv. 2007;62(5):327–34. doi: 10.1097/01.ogx.0000261643.11301.56.

30. Al-Zirqi I, Daltveit AK, Vangen S. Maternal outcome after complete uterine rupture. Acta Obstet Gynecol Scand. 2019;98(8):1024–31. doi: 10.1111/aogs.13579.

31. Desta M, Kassa GM, Getaneh T, Sharew Y, Alemu AA, Birhanu MY, et al. Maternal and perinatal mortality and morbidity of uterine rupture and its association with prolonged duration of operation in Ethiopia: A systematic review and meta-analysis. PLoS One. 2021;16(4):e0245977. doi: 10.1371/journal.pone.0245977.

32. Al-Zirqi I, Daltveit AK, Vangen S. Infant outcome after complete uterine rupture. Am J Obstet Gynecol. 2018;219(1):109.e1-109.e8. doi: 10.1016/j.ajog.2018.04.010.

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2023/06/30
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