Primarne intestinalne limfangiektazije kod odraslih – dijagnostički i terapijski izazov

  • Tatiana Jocic Clinical Center of Vojvodina, Clinic of Gastroenterology and Hepatology
  • Olgica Latinovic Bosnjak University of Novi Sad, Medical faculty, Novi Sad, Serbia
  • Mirjana Zivojinov University of Novi Sad, Medical faculty, Novi Sad, Serbia
  • Mirjana Stojsic
  • Jelena Ilic Sabo
DOI: https://doi.org/10.2298/VSP160210320J
Ključne reči: dijareja;, limfangiektazija;, hipoalbuminemija;, limfocitopenija;, enteropatije sa gubitkom proteina

Sažetak


Uvod. Primarne intestinalne limfangiektazije su retko oboljenje koje karakterišu abnormalno dilatirani crevni limfni sudovi i ekstenzivan enterični gubitak limfe koja je bogata proteinima plazme, limfocitima i hilomikronima. Osnovne karakteristike oboljenja su hipoalbuminemija, hipogamaglobulinemija, limfocitopenija, ređe deficit liposolubilnih vitamina i anemija. Osim primarne, limfangiektazije mogu biti i sekundarne, u sklopu celijakije, malignih, infektivnih i zapaljenskih bolesti tankog creva, fibroze, bolesti jetre i kardiovaskularnih oboljenja. Prikaz bolesnika. Muškarac, star 33 godine, javio se na pregled sa tegobama u vidu proliva i edema potkolenica. Dijagnoza je postavljena patohistološkim pregledom biopsija tankog creva pri double balloon enteroskopiji gde su promene viđene samo u jednom segmentu pregledanog creva, što je kasnije potvrđeno i videoendoskopskom kapsulom. Zaključak. Dijagnoza intestinalnih limafangiektazija postavlja se uglavnom pre treće godine života, ali može se dijagnostikovati i kod starijih osoba. Osnov dijagnoze je patohistološka analiza bioptata sluznice creva dobijenih endoskopskim procedurama. Dijagnoza primarnih intestinalnih limfangiektazija se postavlja i isključivanjem sekundarnih uzroka.

Biografije autora

Tatiana Jocic, Clinical Center of Vojvodina, Clinic of Gastroenterology and Hepatology

specijalista interne medicine- gastroenterolog,

asistent u nastavi katedre za internu medicinu, Medicinski fakultet, Univerzitet u Novom Sadu

Olgica Latinovic Bosnjak, University of Novi Sad, Medical faculty, Novi Sad, Serbia
Clinical Centre of Vojvodina, Clinic for gastroenterology and hepatology, Novi Sad, Serbia
Mirjana Zivojinov, University of Novi Sad, Medical faculty, Novi Sad, Serbia

Clinical centre of Vojvodina, Center for Pathology and Histology, Novi Sad, Serbia

Mirjana Stojsic

Institute of Child and Youth Health Care, Department of Gastroenterohepatology and Nutrition, Novi Sad, Serbia

 

Jelena Ilic Sabo
Clinical centre of Vojvodina, Center for Pathology and Histology, Novi Sad, Serbia

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Objavljeno
2020/10/22
Broj časopisa
Vol. 75 Br. 1 (2018)
Rubrika
Prikaz bolesnika