An economic evaluation of phacoemulsification and extracapsular cataract extraction in cataract surgery

  • Katarina Radujević University of Belgrade, Faculty of Pharmacy, Department of Social Pharmacy and Pharmacy Legislation
  • Nataša Bogavac Stanojević University of Belgrade, Faculty of Pharmacy, Department of Medical Biochemistry
  • Rade Nedeljković General Hospital Kruševac
  • Dragana Lakić University of Belgrade, Faculty of Pharmacy, Department of Social Pharmacy and Pharmacy Legislation
Keywords: cataract;, cost-benefit analysis;, ophthalmologic surgical procedures;, phacoemulsification;, economics, pharmaceutical;, serbia

Abstract


Background/Aim. Cataract surgery is one of the most often performed surgical interventions. The predominant method in Western countries is phacoemulsification, while in developing countries, the extracapsular cataract extraction (ECCE) method remains popular. The aim of the study was to evaluate the cost-effectiveness of these two cataract surgery techniques from the provider’s perspective if operation complications were the outcome of the interest. Methods. The data were obtained from the Department of Ophthalmology of the General Hospital Kruševac during a one-year period. A total of 1,179 surgeries by five surgeons were performed. The cost-effectiveness was evaluated using the decision tree. All probabilities were calculated based on the likelihood of the occurrence during the study period. Only direct costs were considered, and values were taken from the documentation at the hospital and the official price list of health services. One- and two-way sensitivity analyses were performed. Results. The total cost per patient in the phacoemulsification group was 71,008.70 Serbian dinars (RSD), while the total cost in the ECCE group was 74,340.36 RSD. At the same time, phacoemulsification shows higher effectiveness than the ECCE method, with 87% and 57% of patients without complications, respectively. With these results, phacoemulsification was the dominant strategy compared to ECCE. The sensitivity analysis revealed that the results are sensitive to the number of performed operations per year. Conclusion. The phacoemulsification technique seems to be the preferred technique for cataract surgery. All the investment in phacoemulsification equipment and consumables is justified if the number of surgeries per year exceeds 350.

Author Biographies

Nataša Bogavac Stanojević, University of Belgrade, Faculty of Pharmacy, Department of Medical Biochemistry

Katedra za medicinsku biohemiju

Dragana Lakić, University of Belgrade, Faculty of Pharmacy, Department of Social Pharmacy and Pharmacy Legislation

Department for Social Pharmacy and Pharmacy Legislation

References

800x600

Normal

0

false

false

false

EN-US

X-NONE

X-NONE

MicrosoftInternetExplorer4

DefSemiHidden="false" DefQFormat="false" DefPriority="99"

LatentStyleCount="371">

UnhideWhenUsed="true" QFormat="true" Name="heading 2"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 3"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 4"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 5"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 6"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 7"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 8"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 9"/>

Name="index 1"/>

Name="index 2"/>

Name="index 3"/>

Name="index 4"/>

Name="index 5"/>

Name="index 6"/>

Name="index 7"/>

Name="index 8"/>

Name="index 9"/>

UnhideWhenUsed="true" Name="toc 1"/>

UnhideWhenUsed="true" Name="toc 2"/>

UnhideWhenUsed="true" Name="toc 3"/>

UnhideWhenUsed="true" Name="toc 4"/>

UnhideWhenUsed="true" Name="toc 5"/>

UnhideWhenUsed="true" Name="toc 6"/>

UnhideWhenUsed="true" Name="toc 7"/>

UnhideWhenUsed="true" Name="toc 8"/>

UnhideWhenUsed="true" Name="toc 9"/>

Name="Normal Indent"/>

Name="footnote text"/>

Name="annotation text"/>

Name="header"/>

Name="footer"/>

Name="index heading"/>

UnhideWhenUsed="true" QFormat="true" Name="caption"/>

Name="table of figures"/>

Name="envelope address"/>

Name="envelope return"/>

Name="footnote reference"/>

Name="annotation reference"/>

Name="line number"/>

Name="page number"/>

Name="endnote reference"/>

Name="endnote text"/>

Name="table of authorities"/>

Name="macro"/>

Name="toa heading"/>

Name="List"/>

Name="List Bullet"/>

Name="List Number"/>

Name="List 2"/>

Name="List 3"/>

Name="List 4"/>

Name="List 5"/>

Name="List Bullet 2"/>

Name="List Bullet 3"/>

Name="List Bullet 4"/>

Name="List Bullet 5"/>

Name="List Number 2"/>

Name="List Number 3"/>

Name="List Number 4"/>

Name="List Number 5"/>

Name="Closing"/>

Name="Signature"/>

UnhideWhenUsed="true" Name="Default Paragraph Font"/>

Name="Body Text"/>

Name="Body Text Indent"/>

Name="List Continue"/>

Name="List Continue 2"/>

Name="List Continue 3"/>

Name="List Continue 4"/>

Name="List Continue 5"/>

Name="Message Header"/>

Name="Salutation"/>

Name="Date"/>

Name="Body Text First Indent"/>

Name="Body Text First Indent 2"/>

Name="Note Heading"/>

Name="Body Text 2"/>

Name="Body Text 3"/>

Name="Body Text Indent 2"/>

Name="Body Text Indent 3"/>

Name="Block Text"/>

Name="Hyperlink"/>

Name="FollowedHyperlink"/>

Name="Document Map"/>

Name="Plain Text"/>

Name="E-mail Signature"/>

Name="HTML Top of Form"/>

Name="HTML Bottom of Form"/>

Name="Normal (Web)"/>

Name="HTML Acronym"/>

Name="HTML Address"/>

Name="HTML Cite"/>

Name="HTML Code"/>

Name="HTML Definition"/>

Name="HTML Keyboard"/>

Name="HTML Preformatted"/>

Name="HTML Sample"/>

Name="HTML Typewriter"/>

Name="HTML Variable"/>

Name="Normal Table"/>

Name="annotation subject"/>

Name="No List"/>

Name="Outline List 1"/>

Name="Outline List 2"/>

Name="Outline List 3"/>

Name="Table Simple 1"/>

Name="Table Simple 2"/>

Name="Table Simple 3"/>

Name="Table Classic 1"/>

Name="Table Classic 2"/>

Name="Table Classic 3"/>

Name="Table Classic 4"/>

Name="Table Colorful 1"/>

Name="Table Colorful 2"/>

Name="Table Colorful 3"/>

Name="Table Columns 1"/>

Name="Table Columns 2"/>

Name="Table Columns 3"/>

Name="Table Columns 4"/>

Name="Table Columns 5"/>

Name="Table Grid 1"/>

Name="Table Grid 2"/>

Name="Table Grid 3"/>

Name="Table Grid 4"/>

Name="Table Grid 5"/>

Name="Table Grid 6"/>

Name="Table Grid 7"/>

Name="Table Grid 8"/>

Name="Table List 1"/>

Name="Table List 2"/>

Name="Table List 3"/>

Name="Table List 4"/>

Name="Table List 5"/>

Name="Table List 6"/>

Name="Table List 7"/>

Name="Table List 8"/>

Name="Table 3D effects 1"/>

Name="Table 3D effects 2"/>

Name="Table 3D effects 3"/>

Name="Table Contemporary"/>

Name="Table Elegant"/>

Name="Table Professional"/>

Name="Table Subtle 1"/>

Name="Table Subtle 2"/>

Name="Table Web 1"/>

Name="Table Web 2"/>

Name="Table Web 3"/>

Name="Balloon Text"/>

Name="Table Theme"/>

Name="List Paragraph"/>

Name="Intense Quote"/>

Name="Subtle Emphasis"/>

Name="Intense Emphasis"/>

Name="Subtle Reference"/>

Name="Intense Reference"/>

UnhideWhenUsed="true" Name="Bibliography"/>

UnhideWhenUsed="true" QFormat="true" Name="TOC Heading"/>

Name="Grid Table 1 Light Accent 1"/>

Name="Grid Table 6 Colorful Accent 1"/>

Name="Grid Table 7 Colorful Accent 1"/>

Name="Grid Table 1 Light Accent 2"/>

Name="Grid Table 6 Colorful Accent 2"/>

Name="Grid Table 7 Colorful Accent 2"/>

Name="Grid Table 1 Light Accent 3"/>

Name="Grid Table 6 Colorful Accent 3"/>

Name="Grid Table 7 Colorful Accent 3"/>

Name="Grid Table 1 Light Accent 4"/>

Name="Grid Table 6 Colorful Accent 4"/>

Name="Grid Table 7 Colorful Accent 4"/>

Name="Grid Table 1 Light Accent 5"/>

Name="Grid Table 6 Colorful Accent 5"/>

Name="Grid Table 7 Colorful Accent 5"/>

Name="Grid Table 1 Light Accent 6"/>

Name="Grid Table 6 Colorful Accent 6"/>

Name="Grid Table 7 Colorful Accent 6"/>

Name="List Table 1 Light Accent 1"/>

Name="List Table 6 Colorful Accent 1"/>

Name="List Table 7 Colorful Accent 1"/>

Name="List Table 1 Light Accent 2"/>

Name="List Table 6 Colorful Accent 2"/>

Name="List Table 7 Colorful Accent 2"/>

Name="List Table 1 Light Accent 3"/>

Name="List Table 6 Colorful Accent 3"/>

Name="List Table 7 Colorful Accent 3"/>

Name="List Table 1 Light Accent 4"/>

Name="List Table 6 Colorful Accent 4"/>

Name="List Table 7 Colorful Accent 4"/>

Name="List Table 1 Light Accent 5"/>

Name="List Table 6 Colorful Accent 5"/>

Name="List Table 7 Colorful Accent 5"/>

Name="List Table 1 Light Accent 6"/>

Name="List Table 6 Colorful Accent 6"/>

Name="List Table 7 Colorful Accent 6"/>

/* Style Definitions */

table.MsoNormalTable

{mso-style-name:"Table Normal";

mso-tstyle-rowband-size:0;

mso-tstyle-colband-size:0;

mso-style-noshow:yes;

mso-style-priority:99;

mso-style-parent:"";

mso-padding-alt:0cm 5.4pt 0cm 5.4pt;

mso-para-margin:0cm;

mso-para-margin-bottom:.0001pt;

mso-pagination:widow-orphan;

font-size:10.0pt;

font-family:"Times New Roman",serif;}

1.      Nikolić Lj. Cataract surgery. 1st ed. Belgrade: Zavod za udžbenike; 2009. (Serbian)

2.      WHO. Blindness and vision impairment. Available from: https://www.who.int/en/news-room/fact-sheets/detail/blind
/>ness-and-visual-impairment  [accessed 2021 April 21].

3.      National Eye Institute. Cataract Data and Statistics. Available from: https://www.nei.nih.gov/learn-about-eye-health/resour
/>ces-for-health-educators/eye-health-data-and-statistics/catarac
t-data-and-statistics [accessed 2021 April 21].

4.      Prokofyeva E, Wegener A, Zrenner E. Cataract prevalence and prevention in Europe: a literature review. Acta Ophthalmol 2013; 91(5): 395‒405.

5.      Hugosson M, Ekström C. Prevalence and risk factors for age-related cataract in Sweden. Ups J Med Sci 2020; 125(4): 311‒5.

6.      Institute of Public Health "Dr. Milan Jovanovic Batut". Selected health indicators for 2017. Belgrade: Institute of Public Health “Dr. Milan Jovanovic Batut”; 2018. (Serbian)

7.      American Academy of Ophthalmology. Cataract in the Adult Eye Preferred Practice Pattern 2016. San Francisco, CA: American Academy of Ophthalmology; 2016.

8.      Manaf MRA, Aljunid SM, Annuar FH, Leong CK, Mansor N. Cost-effectiveness analysis of cataract surgery with intraocular lens implantation: extracapsular cataract extraction versus phacoemulsification. Med J Indones 2007; 16(1): 25‒31.

9.      Assia-Pacific Association of Cataract & Refractive Surgeons (APACRS). Principles of Preferred Practice in Cataract Surgery. Available from: https://apacrs.org/ppp_cataract_EN
/>/index.html#6

10.   Republic Health Insurance Fund. Rulebook on prices of health services at the secondary and tertiary level. ("Sl. glasnik RS", br. 55/2019). (Serbian)

11.   Thevi T, Reddy SC, Shantakumar C. Outcome of phacoemulsification and extracapsular cataract extraction: A study in a district hospital in Malaysia. Malays Farm Physician 2014; 9(2): 41‒7.

12.   Clark A, Morlet N, Ng JQ, Preen DB, Semmens JB. Whole population trends in cataract surgery over 22 years in Western Australia. Ophthalmology 2011; 118(6): 1055–60.

13.   Kara N Jr, Sirtoli MG, Santhiago MR, Parede TR, Espíndola RF, Carvalho Rde S. Phacoemulsification versus extracapsular extraction: governmental costs. Clinics (Sao Paulo) 2010; 65(4): 357‒61.

14.   Rochmah TN, Wulandari A, Dahlui M, Ernawaty, Wulandari RD. Cost Effectiveness Analysis Using Disability-Adjusted Life Years for Cataract Surgery. Int J Environ Res Public Health 2020; 17(16): 6010.

15.   Muralikrishnan R, Venkatesh R, Prajna NV, Frick KD. Economic cost of cataract surgery procedures in an established eye care centre in Southern India. Ophthalmic Epidemiol 2004; 11(5): 369‒80.

16.   Agarwal A. Measuring the cost-effectiveness of cataract surgery. Available from: https://www.healio.com/news/ophthal
/>mology/20120325/measuring-the-cost-effectiveness-of-cataract-surgery [accessed 2022 February 03].

17.   Asimakis P, Coster DJ, Lewis DJ. Cost effectiveness of cataract surgery. A comparison of conventional extracapsular surgery and phacoemulsification at Flinders Medical Centre. Aust N Z J Ophthalmol 1996; 24(4): 319‒25.

18.   Loo CY, Kandiah M, Arumugam G, Goh PP, John E, Gurusami B, et al. Cost efficiency and cost effectiveness of cataract surgery at the Malaysian Ministry of Health ophthalmic services. Int Ophthalmol 2004; 25(2): 81‒7.

19.   de Silva SR, Riaz Y, Evans JR. Phacoemulsification with posterior chamber intraocular lens versus extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens for age-related cataract. Cochrane Database Syst Rev 2014; (1): CD008812.

20.   Griffiths UK, Bozzani FM, Gheorghe A, Mwenge L, Gilbert C. Cost-effectiveness of eye care services in Zambia. Cost Eff Resour Alloc 2014; 12: 6.

21.   Agarwal A, Kumar DA. Cost-effectiveness of cataract surgery. Curr Opin Ophthalmol 2011; 22(1): 15‒8.

22.   Eye Care Comparative Effectiveness Research Team (ECCERT). Hiratsuka Y, Yamada M, Akune Y, Murakami A, Okada AA, Yamashita H, et al. Cost-utility analysis of cataract surgery in Japan: a probabilistic Markov modeling study. Jpn J Ophthalmol 2013; 57(4): 391‒401.

23.   Lansingh VC, Carter MJ, Martens M. Global cost-effectiveness of cataract surgery. Ophthalmology 2007; 114(9): 1670‒8.

24.   Baltussen R, Sylla M, Mariotti SP. Cost-effectiveness analysis of cataract surgery: a global and regional analysis. Bull World Health Organ 2004; 82(5): 338‒45.

25.   Nowak MS, Grabska-Liberek I, Michalska-Małecka K, Grzybowski A, Kozioł M, Niemczyk W, et al. Incidence and Characteristics of Cataract Surgery in Poland, during 2010-2015. Int J Environ Res Public Health 2018; 15(3): 435.

26.   Randleman JB, Wolfe JD, Woodward M, Lynn MJ, Cherwek DH, Srivastava SK. The Resident Surgeon Phacoemulsification Learning Curve. Arch Ophthalmol 2007; 125(9): 1215‒9.

Published
2023/02/13
Section
Original Paper