Giant left main coronary artery aneurysm

Srpski

  • Kristina Andjelković University Clinical Center of Serbia, Cardiology Clinic, Belgrade, Serbia
  • Kontakt telefon: 063/8010519 Institute for Cardiovascular Diseases “Dedinje”, Belgrade, Serbia
  • Mladen Kočica University Clinical Center of Serbia, Clinic for Cardiac Surgery, Belgrade, Serbia
  • Kontakt: 064/2859737 University of Kragujevac, Faculty of Medical Sciences, Kragujevac, Serbia;
  • Branislava Ivanović University Clinical Center of Serbia, Cardiology Clinic, Belgrade, Serbia
Keywords: cardiac catheterization, coronary aneurysm, coronary angiography, cardiac surgical procedures, diagnosis, non-st elevated myocardial infarction

Abstract


Introduction. Coronary artery aneurysms (CAAs) are rare disorders, especially the left main CAA. In the literature, there are several reported cases with CAAs, various localization, size, clinical presentation, and way of treatment. There is no unique consensus about the most adequate treatment for these patients; however, surgery is still preferable, although there are some new experiences of percutaneous treatment. The decision is made for each patient individually. We report a case of giant left main CAA, with acute coronary syndrome and heart failure presentation, surgically treated. Case report. A 66-year-old female patient was admitted to the emergency department of our clinic due to chest pain and dyspnea. Acute non-ST-elevation segment myocardial infarction (STEMI) of anterolateral localization was diagnosed (creatine kinase max 1,111 U/L, troponin T 3.754 ng/mL), complicated with acute heart failure. Heart catheterization and coronary angiography revealed a giant saccular, 3.5 × 3.5 mm left main CAA full with thrombi, compressing the proximal segments of the left anterior descending and circumflex artery. Conclusion. Giant left main CAAs are rare pathologic findings, and there are no established principles for treatment. Although the percutaneous way of treatment is now available in selected cases, the surgical approach is still preferred for these patients.

References

1.      Abou Sherif S, Ozden Tok O, Taşköylü Ö, Goktekin O, Kilic ID. Coronary Artery Aneurysms. A Review of the Epidemiology, Pathophysiology, Diagnosis, and Treatment. Front Cardiovasc Med 2017; 4: 24.

2.      Topaz O, DiSciascio G, Crowley MJ, Goudreau E, Soffer A, Nath A, et al. Angiographic features of the left main coronary artery aneurysms.  Am J Cardiol 1991; 67(13): 1139–42.

3.      Kawsara A, Núñez Gil IJ, Alqahtani F, Moreland J, Rihal CS, Alkhouli M. Management of Coronary Artery Aneurysms. JACC Cardiovasc Interv 2018; 11(13): 1211–23.

4.      Sheikh AS, Hailan A, Kinnaird T, Choudhury A, Smith D. Coronary Artery Aneurysm: Evaluation, Prognosis, and Proposed Treatment Strategies. Heart Views  2019; 20(3): 101–8.

5.      Díaz-Zamudio M, Bacilio-Pérez U, Herrera-Zarza MC, Meave-González A, Alexanderson-Rosas E, Zambrana-Balta GF, et al. Coronary artery aneurysms and ectasia: role of coronary CT angiography. Radiographics 2009; 29(7): 1939–54.

6.      Li D, Wu Q, Sun L, Song Y, Wang W, Pan S, et al. Surgical treatment of giant coronary artery aneurysm. Thorac Cardiovasc Surg 2005; 130(3): 817–21.

7.      Matsuno Y, Fukumoto Y, Ishida N, Shimabukuro K, Takemura H. Mycotic left main coronary artery aneurysm following double-valve replacement for active infective endocarditis. Ann Thorac Cardiovasc Surg 2013; 19(1): 70–2.

8.      Li X, Song L, Guo H, Jin J, Xu M. Surgical Repair of Congenital Coronary Artery Fistula With Giant Aneurysm. Heart Surg Forum 2020; 23(2): e151–3.

9.      Deitz R, Okusanya O, Kilic A, Emerel L, Sultan I. Giant coronary artery aneurysm masquerading as an anterior mediastinal mass. Gen Thorac Cardiovasc Surg 2021; 69(3): 534–7.

10.   Lima B, Varma SK, Lowe JE. Nonsurgical management of left main coronary artery aneurysms: report of 2 cases and review of the literature. Tex Heart Inst J 2006; 33(3): 376–9.

11.   Yan Q, Ning L, Jian Y, Yang W, Yuan Q, Du Z. Could the Novel Oral Anticoagulants Be Used for Coronary Artery Aneurysm? Case Rep Med 2020; 2020: 5073814.

12.   Tengiz I, Ercan E, Aliyev E, Sekuri C, Duman C, Altuglu I. Elevated levels of matrix metalloprotein-3 in patients with coronary aneurysm: A case control study. Curr Control Trials Cardiovasc Med 2004; 5(1): 10.

13.   Gülec S, Aras O, Atmaca Y, Akyürek O, Hanson NQ, Sayin T, et al. Deletion polymorphism of the angiotensin I converting enzyme gene is a potent risk factor for coronary artery ectasia.  Heart 2003; 89(2): 213–4.

14.   Will M, Kwok CS, Nagaraja V, Potluri R, Weiss TW, Mascherbauer J, et al. Outcomes of Patients Who Undergo Elective Covered Stent Treatment for Coronary Artery Aneurysms. Cardiovasc Revasc Med 2022; 36: 91–6.

15.   Burzotta F, Trani C, Romagnoli E, Mazzari MA, Savino M, Schiavoni G, et al. Percutaneous treatment of a large coronary aneurysm using the self-expandable Symbiot PTFE-covered stent. Chest 2004; 126(2): 644–5.

16.   Win HK, Polsani V, Chang SM, Kleiman NS. Stent-Assisted Coil Embolization of a Large Fusiform Aneurysm of Proximal Anterior Descending Artery: Novel Treatment for Coronary Aneurysms. Circ Cardiovasc Interv 2012; 5(1): e3–5.

17.   Dai HL, Guang XF, Lu YB, Xue Q, Zhang WH. Multiple Overlapping Stents Might Be a Promising Therapeutic Target for Coronary Artery Aneurysms. JACC Cardiovasc Interv 2018; 11(21): 2234–5.

18.   Chou HH, Huang HL, Ko YL. Acute Myocardial Infarction Due to Prolapse of Covered Stent Into Coronary Artery Aneurysm. JACC Cardiovasc Interv 2018; 11(18): e147–8.

19.   Matsubayashi K, Asai T, Nishimura O, Kinoshita T, Ikegami H, Kambara A, et al. Giant Coronary Artery Aneurysm in the Left Main Coronary Artery: A Novel Surgical Procedure. Ann Thorac Surg 2008; 85(6): 2130–2.

20.   Soletti GJ, Lau C, Cancelli G, Robinson NB, Audisio K, Girardi LN, et al. Surgical repair of a giant coronary artery aneurysm. J Card Surg 2021; 36(9): 3396–8.

21.   Baman TS, Cole JH, Devireddy CM, Sperling LS. Risk factors and outcomes in patients with coronary artery aneurysms. Am J Cardiol 2004; 93(12): 1549–51.

Published
2023/08/28
Section
Case report