Uticaj materijala za šivenje na zarastanje rana – eksperimentalna studija na psima
Sažetak
Uvod/Cilj. Najčešći materijali koji se ugrađuju u organizam čoveka jesu materijali za šavove koji se klasifikuju prema više kriterijuma, najčešće prema poreklu, strukturi i osobinama. Osobine šavnog materijala odnose se na njegovu resorptivnost, odnosno neresorptivnost. Pri upotrebi resorptivnih materijala važno je utvrditi da li njegova resorptivnost i tenziona snaga pomažu zarastanju rane u funkciji vremena. Sami konci mogu postati izvor upale koji može sniziti ili ugrozititi potencijal reparacije i regeneracije. Cilj ove eksperimentalne studije bio je da se utvrdi da li se brzina resorpcije i stepen lokalne reakcije tkiva razlikuju od podataka koje daje proizvođač, da li postoje razlike između primenjenih materijala za šavove, kao i koji od njih bolje utiče na zarastanje rane. Metode. Eksperimentalna studija sprovedena je na šest nemačkih ovčara, kojima su načinjene po tri identične incizije u sva četiri kvadranta (sa leve i desne strane u gornjoj i donjoj vilici). Tako je kod svake životinje formirano 12 horizontalnih incizija, dužine 10 mm, međusobno udaljenih 20–25 mm, koje su ušivene trima različitim šavnim materijalima: ketgat, Dexon®, Vicryl-Rapide®, a eksperiment je okončan patohistološkim pregledom preparata, uzetih trećeg, sedmog, četrnaestog i dvadesetprvog postoperativnog dana, kako bi se video efekat zarastanja i stepen lokalne reakcije. Rezultati. Rezultati pokazuju da najbržu resorpciju ima ketgat, a najsporiju Dexon®. Najmanji stepen lokalne reakcije izaziva Vicryl-Rapide®, a najveći Dexon®. Zaključak. Idealan materijal za šavove ne postoji. Različiti faktori koji su povezani sa pacijentom takođe utiču na proces zarastanja rane.
Reference
Capperauld I. Suture materials: a review. Clin Mater 1989; 4: 3−12.
Margota R. The story of medicine. New York: Golden Press; 1968.
Sabiston DC. Textbook of surgery. 14th ed. Philadelphia: WB Saunders Co; 1991.
Snyder CC. On the history of suture. Plast Reconstr Surg 1976; 58(4): 401−6.
LaBagnara J Jr. A review of absorbable suture materials in head & neck surgery and introduction of monocryl: a new absorba-ble suture. Ear Nose Throat J 1995; 74(6): 409−15.
Kostić I. The influence of suture material and the type of stitching up upon tracheal anastomonis healing [dissertation]. Niš: Faculty of Medicine, University of Niš; 1989. (Serbian)
Capanglou D. (1999-2000) Spring term sutures. Available from: http//www.biometu.edu.tr/biomed/sutures.htm
O'Neal RB, Alleyn CD. Suture materials and techniques. Curr Opin Periodontol 1997; 4: 89−95.
Stone IK, von Fraunhofer JA, Masterson BJ. A comparative study of suture materials: chromic gut and chromic gut treated with glycerin. Am J Obstet Gynecol 1985; 151(8): 1087−939.
Stone IK. Suture materials. Clin Obstet Gynecol 1988; 31(3): 712−7.
Racey GL, Wallace WR, Cavalaris CJ, Marquard JV. Comparison of a polyglycolic-polylactic acid suture toblack silk and plain catgut in human oral tissues. J Oral Surg 1978; 36: 776−70.
Guyuron B, Vaughan C. A comparison of absorbable and non-absorbable suture materials for skin repair. Plast Reconstr Surg 1992; 89(2): 234−6.
Peterson L, Ellis E, Hupp JR, Tucker MR. Contemporary Oral and Maxillofacial Surgery. 3rd ed. St Louis, Mo: Mosby Year-Book; 1998.
Aderriotis D, Sàndor GK. Outcomes of irradiated polyglactin 910 Vicryl Rapide fast-absorbing suture in oral and scalp wounds. J Can Dent Assoc 1999; 65(6): 345−7.
Quayle AA, El Bawdrawy H. Clinical and Experimental Studies with a Resorbable Transosseous Ligature. Br J Oral Maxillofac Surg 1984; 22(1): 24−9.
Pini Prato GP, Cortellini P, Agudio G, Clauser C. Human fibrin glue versus sutures in periodontal surgery. J Periodontol 1987; 58(6): 426−31.
Mirković S. Influence of suturing material on wound healing af-ter mucoperiostal incision [thesis]. Novi Sad: Faculty of Denti-stry, University of Novi Sad; 2000. (Serbian)
Greene JC, Vermillion JR. Simplified oral hygiene index. J Am Dent Assoc 1964; 68: 7−13.
Loë H. The Gingival Index, the Plaque Index and the Reten-tion Index Systems. J Periodontol 1957; 38: 610−6.
Lalević P. Anestesiology IV. Beograd: Zavod za udžbenike i nastavna sredstva; 1999. (Serbia)
Nary Filho H, Matsumoto MA, Batista AC, Lopes LC, de Góes FC, Consolaro A. Comparative Study of Tissue Response to Polyg-lecaprone 25, Polyglactin 910 and Polytetrafluorethylene Suture Materials in Rats. Braz Dent J 2002; 13(2): 86−91.
Certosimo FJ, Nicoll BK, Nelson RR, Wolfgang M. Wound healing and repair: a review of the art and science. Gen Dent 1998; 46(4): 362−9.
Beswada RS, Jamiolkowski DD, Lee IY, Agarwal V, Persivale J, Trenka-Benthin S, et al. Monocryl suture, a new ultra-pliable absorbable monofilament suture. Biomaterials 1995; 16(15): 1141−8.
Shaw RJ, Negus TW, Mellor TK. A prospective clinical evaluation of the longevity of resorbable sutures in oral mucosa. Br J Oral Maxillofac Surg 1996; 34(3): 252−4.
Nary Filho H, Okamoto T, Padovan LEM. Estudo comparativo da resposta tecidual frente a fios de sutura de catgut e polig-lecaprone 25 em subcutaneo de ratos. Salusvita 1996; 15: 127−42.
McCaul LK, Bagg J, Jenkins WM. Rate of loss of irradiated po-lyglactin 910 (Vicryl Rapide) from the mouth: a prospective study. Br J Oral Maxillofac Surg 2000; 38(4): 328−30.
Duprez K, Bilweis J, Merle M. Experimental and clinical study of fast absorption cutaneous suture material. Ann Chir Main 1988; 7(1): 91−6.
Winstanley RP. The use of sutures in the mouth. Br J Maxillofac Surg 1985; 23(5): 381−5.
Craig PH, Wiliams JA, Davis KW, Magoun AD, Levy AJ, Bogdansky S, et al. Somerville, New Jersey. A biologic comparison of Polyglactin 910 and Polyglycolic acid synthetic absorbable su-tures. Surg Gynecol Obstet 1975; 141(1): 1−9.
Mirković S, Đurđević-Mirković T. Influence of different types of surgical suture materials on mehanical damage of oral mucosa. Med Pregled 2011; 64(3−4): 157−60. (Serbian)
Mirković S, Đurđević-Mirković T, Bajkin B, Šarčev I. Choice of surgical suture material used in oral cavity-clinacal study. Med Pregled 2010; 63(7−8): 497−501. (Serbian)
Wallace WR, Maxwel GR, Cavalaris CJ. Comparison of polygli-colic acid to black silk, chromic, and plain catgut in human oral tissues. J Oral Surgery 1970; 28(10): 739−16.
