Sarcoidosis of the pleura – A case report

Dragana Jovanović; Violeta Vučinić; Ruža Stević; Marina Roksandić-Milenković; Natalija Samardžić; Marta Velinović; Mihailo Stjepanović

doi:10.2298/2391

Dragana Jovanović Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Violeta Vučinić Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Ruža Stević Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Center for Radiology and Magnetic Resonance Imaging, Clinical Center of Serbia, Belgrade, Serbia
Marina Roksandić-Milenković Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia
Natalija Samardžić Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia
Marta Velinović Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia
Mihailo Stjepanović Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia

DOI: https://doi.org/10.2298/2391

Keywords: sarcoidosis, pleural effusion, biopsy, therapeutics,

Abstract

Introduction. Pleural involvement is an uncommon manifestation of sarcoidosis. It may manifest as pleural effusion, pneumothorax, pleural thickening and nodules, hydropneumothorax, trapped lung, hemothorax, or chylothorax. The incidence of pleural effusion with sarcoidosis ranges from 0% to 5% but has been reported to be as high as 7.5%. Pleural effusions complicate sarcoidosis in < 3% of patients. Case report. We reported a 64-year-old male patient with chronic multiorgan sarcoidosis. This patient developed pleural sarcoidosis with massive pleural effusion several years after the diagnosis of sarcoidosis. A definitive diagnosis of a sarcoid pleural effusion was based on a biopsy demonstrating noncaseating granuloma. The patient responded well to the treatment (methotrexate and methylprednisolone) with a complete withdrawal of pleural effusion following five weeks of the treatment beginning. Conclusion. The presented patient is a rare case of pleural involvement of sarcoidosis with massive effusion, who responded well to the treatment.

Author Biographies

Dragana Jovanović, Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Sistem neće strelicama da napravi adekvatan raspored autora Dr Jovanovic je 1 autor

Violeta Vučinić, Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Sistem neće strelicama da napravi adekvatan raspored autora Dr Vučinić je 2 autor

Ruža Stević, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Center for Radiology and Magnetic Resonance Imaging, Clinical Center of Serbia, Belgrade, Serbia

Sistem neće strelicama da napravi adekvatan raspored autora Dr Stević je 3 autor

Marina Roksandić-Milenković, Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia

Sistem neće strelicama da napravi adekvatan raspored autora Dr Roksandić je 4 autor

Natalija Samardžić, Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia

Sistem neće strelicama da napravi adekvatan raspored autora Dr Samardžić je 5 autor

Marta Velinović, Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia

Sistem neće strelicama da napravi adekvatan raspored autora Dr Velinović je 6 autor

Mihailo Stjepanović, Clinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Serbia

Sistem neće strelicama da napravi adekvatan raspored autora Dr Stjepanović je 7 autor

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