Unilateral galactocele in a male infant
Abstract
Introduction. Galactocele, generally occuring in young women during or after lactation, is an extremely rare cause of breast enlargement in infants and children of exclusively male gender. Only 26 cases have been published so far, including two our cases. Case report. We described unilateral, cystic, breast enlargement, without any endocrinologic and other abnormalities in a 29-month-old boy. A typical clinical and histopathologic presentation of galactocele was followed with a complete excision. Conclusion. This was a 27th well documented case of galactocele in a male infant with typical clinical and histopathologic presentation. There are several hypotheses regarding etiology of the lesion, but it is likely to be multifactorial. Because of its extreme rarity, there are some difficulties in differential diagnosis and treatment options of galactocele in male infants.
References
Boyle M, Lakhoo K, Ramani P. Galactocele in a male infant: case report and review of literature. Pediatr Pathol 1993; 13(3): 305−8.
Doneray H, Ozkan B, Erdogan F, Salman AB. Bilateral galactocele in a male infant. Turk J Med Sci 2008; 38(5): 481−3.
de Chadarévian JP, Arthur LG, Rezvani GA, Duke DS, Davis WJ, et al. The galactocele of male infants: an intriguing entity. Study and reflection about a case, with review of the literature. Pediatr Dev Pathol 2011; 14(2): 144−8.
Vlahovic A, Djuricic S, Todorovic S, Djukic M, Milanovic D, Vujanic GM. Galactocele in male infants: report of two cases and re-view of the literature. Eur J Pediatr Surg 2012; 22(3): 246−50.
Cattani G. On the study of galactocele. Ann Ostet Ginec Pe-diatr 1880; 2: 420−31.
Pettinato G, Manivel JC, Kelly DR, Wold LE, Dehner LP. Lesions of the breast in children exclusive of typical fibroadenoma and gynecomastia. A clinicopathologic study of 13 cases. Pathol Ann 1989; 24(2): 296−328.
Welch ST, Babcock DS, Ballard ET. Sonography of pediatric male breast masses: gynecomastia and beyond. Pediatr Radiol 2004; 34(12): 952−7.
Rahman N, Davenport M, Buchanan C. Galactocele in a male in-fant with congenital hypopituitarism. J Pediatr Endocrinol Me-tab 2004; 17(10): 1451−3.
Tomasi PA, Fanciulli G, Casti T, Delitala G. Persistent hyperpro-lactinemia and bilateral galactocele in a male infant. Int J Pe-diatr Endocrinol 2009; 2009: 578610.
Al Salem AH, Al Nazer M. An unusual cause of breast en-largement in a 5-year-old boy. Pediatr Pathol Mol Med 2002; 21(5): 485−9.
Obrist P, Schwabegger A, Brunhuber T, Schäfer G, Kreczy A. Galac-tocele in a young male patient. Plast Reconstr Surg 2003; 112(1): 186−8.
