Facing dengue fever – our first experience

Dejan Miroslav Cvjetković; Sandra Stefan Mikić; Ivana B. Hrnjaković Cvjetković

doi:10.2298/VSP151117247C

Dejan Miroslav Cvjetković University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Clinical Center of Vojvodina, Clinic for Infectious Disease, Novi Sad, Serbia.
Sandra Stefan Mikić University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Clinical Center of Vojvodina, Clinic for Infectious Disease, Novi Sad, Serbia.
Ivana B. Hrnjaković Cvjetković University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Institute of Public Health of Vojvodina, Center for Virology, Novi Sad, Serbia

DOI: https://doi.org/10.2298/VSP151117247C

Keywords: dengue, diagnosis, signs and symptoms, leukopenia, thrombocytopenia, creatine kinase,

Abstract

Introduction. Dengue fever is a mosquito-borne disease caused by dengue virus, endemic in tropical and subtropical regions, where it is mostly imported from. The most common clinical form is classic dengue fever. We presented the first dengue case microbiologically confirmed in Serbia.
Case report. A 34-year-old male got classic dengue fever after arrival from Cuba. The disease occurred suddenly with fever, myalgias, skin rash, hepatosplenomegaly, cytopenia, abnormal aminotransferase and creatine kinase levels. The diagnosis was confirmed with virological diagnostic methods. Significant leukopenia and thrombocytopenia as well as elevation of serum creatine kinase activity were recorded from the very beginning of hospitalization, but were gradually normalized. The whole duration of hospitalization was accompanied by laboratory signs of liver lesion. The disease had favourable outcome. At hospital discharge, the patient was afebrile, asymptomatic, with discrete erythematous rash on torso and arms, normal hemathological values and creatine kinase level and moderately elevated alanine-aminotransferase level. Conclusion. Considering global climate changes and growing international traffic, our health care service needs to be ready for possible massive outbreaks of dengue and other tropical infectious diseases in forthcoming years.

Author Biographies

Dejan Miroslav Cvjetković, University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Clinical Center of Vojvodina, Clinic for Infectious Disease, Novi Sad, Serbia.

Šef Odseka za herpes virusne infekcije i nejasna febrilna stanja

Vanredni profesor na Katedri za infektivne bolesti

Sandra Stefan Mikić, University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Clinical Center of Vojvodina, Clinic for Infectious Disease, Novi Sad, Serbia.

Načelnik Odeljenja za respiratorne infekcije i nejasna febrilna stanja

Vanredni profesor na Katedri za infektivne bolesti

Ivana B. Hrnjaković Cvjetković, University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Institute of Public Health of Vojvodina, Center for Virology, Novi Sad, Serbia

Šef Odeljenja za kulturu ćelija i drugu virusološku dijagnostiku

Vanredni profesor na Katedri za mikrobiologiju

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