ANALIZA KRATKORO^NE VARIJACIJE I DUGORO^NE PROMENE PRILIKOM ZAMENE SETA REAGENASA U BIOHEMIJSKIM LABORATORIJAMA AKREDITOVANIM OD STRANE NABL-A
Sažetak
Background: Kit lot change in clinical biochemistry labs
leads to variations in patient results. This study planned to
identify variations during 60 reagent lot changes in our laboratory during the period from June 2018 to May 2019.
Methods: A statistical analysis was performed to identify
the difference between patient samples results variations
and QC results. The long term drift was analyzed using a
regression test.
Results: There was a significant difference between the
patient and QC results in 16.7% of reagent lot changes.
Moreover, the extent of variation in QC results was 3.3%.
No long-term drift was seen in three analytes which were
studied using regression analysis.
Conclusions: Our results showed that, during reagent kit lot
change, along with QC material, the patient samples
should also be run in order to identify the variation.
However, this practice is presently ignored by most of the
laboratories. There was no accumulated effect in our laboratory due to reagent kit lot change.
Sva prava zadržana (c) 2020 Sibin Madathan Kandi
Ovaj rad je pod Creative Commons Autorstvo 4.0 međunarodnom licencom.
The published articles will be distributed under the Creative Commons Attribution 4.0 International License (CC BY). It is allowed to copy and redistribute the material in any medium or format, and remix, transform, and build upon it for any purpose, even commercially, as long as appropriate credit is given to the original author(s), a link to the license is provided and it is indicated if changes were made. Users are required to provide full bibliographic description of the original publication (authors, article title, journal title, volume, issue, pages), as well as its DOI code. In electronic publishing, users are also required to link the content with both the original article published in Journal of Medical Biochemistry and the licence used.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.