Advancing Point-of-Care Diagnostics in Community Medicine: Evaluation of the Portable ENNOLIFE HCA-TC-200 Analyzer for Hepatorenal and Urinary Testing

Portable Analyzer for Hepatorenal and Urinary Testing

DOI: https://doi.org/10.5937/jomb0-58353

Sažetak


Background: Accurate and efficient chemical analyzers play a critical role in modern healthcare, particularly in community medicine where early diagnosis and intervention can significantly improve patient outcomes. This study evaluated the diagnostic performance of the novel portable ENNOLIFE HCA-TC-200 analyzer compared to the established Beckman UniCel DxC 880i analyzer, emphasizing its application for point-of-care testing in community settings.

Methods: A total of 600 healthy subjects were recruited from Shuang Ho Hospital, Taiwan. The diagnostic accuracy of ENNOLIFE HCA-TC-200 was validated using clinical chemistry assays, specifically assessing hepatic, renal, and urinary biomarkers. The analyzers were compared based on linearity, inter-method agreement, accuracy, and precision.

Results: The ENNOLIFE HCA-TC-200 analyzer demonstrated diagnostic accuracy and precision comparable to the Beckman UniCel DxC 880i. High linear correlations (R > 0.97) were found for most hepatic, renal, and urinary markers, with minor deviations observed for albumin (R = 0.92) and urine creatinine (R = 0.80), which remained within clinically acceptable diagnostic ranges. Accuracy assessments showed >97% inter-method agreement across all analytes after excluding extreme outliers, with 100% agreement for hepatic and renal markers.

Conclusions: Chronic liver and kidney diseases remain significant public health challenges, especially within community healthcare contexts. The portable ENNOLIFE HCA-TC-200 analyzer effectively addresses these challenges by facilitating rapid, accurate point-of-care diagnostics in community-based settings. This device supports timely disease detection, enhances preventive medicine practices, and promotes personalized healthcare, ultimately contributing to improved community health outcomes.

Biografije autora

Ping-Jen Hu, Shuang-Ho Hospital

I am Ping-Jen Hu, MD, MS, a gastroenterologist at Shuang Ho Hospital in Taiwan, specializing in endoscopic ultrasound (EUS), endoscopic retrograde cholangiopancreatography (ERCP), and advanced biliary-pancreatic interventions. I earned my MD from Chung Shan Medical University in 2010 and completed internal medicine and gastroenterology fellowship training at Shuang Ho Hospital. In 2018, I served at Mackay Memorial Hospital in Taitung, gaining experience in managing gastrointestinal diseases in underserved areas. In 2019, I trained in EUS and cholangioscopy at Kitasato University Endoscopy Center in Japan, focusing on minimally invasive techniques. I obtained my Master’s in Biomedical Sciences from Taitung University in 2021 and received lecturer certification from the Ministry of Education. Returning to Shuang Ho Hospital, I was appointed Director of the Endoscopy Center, leading advancements in biliary-pancreatic endoscopy and training programs. I later became Deputy Director of the Department of Community Medicine, integrating clinical expertise with public health initiatives. My research focuses on chronic kidney disease, biliary-pancreatic diseases, hepatitis, and community medicine, utilizing big data analytics to improve patient outcomes. I have been invited as a speaker and live demonstration expert at national and international conferences, contributing to advancements in endoscopic techniques and gastroenterological healthcare.

Yung-Han Lai, Department of Education, Taipei Municipal Wanfang Hospital, Taipei, Taiwan

I am Yung-Han Lai, M.D., a Postgraduate Year (PGY) physician at Wanfang Municipal Hospital in Taiwan, where I focus on clinical training and research. My passion lies in improving patient care through data-driven insights, evidence-based medicine, and preventive healthcare strategies. I believe that integrating research with clinical practice enhances medical decision-making and leads to better long-term health outcomes for individuals and communities. I earned my Doctor of Medicine (M.D.) from Poznan University of Medical Sciences in 2021, after completing a Bachelor of Arts (B.A.) in Biochemistry at the University of Washington in 2016. My academic background provides a strong foundation in biological sciences and analytical research methodologies, which I actively apply in my medical and scientific work. Building on my passion for family medicine, my research focuses on preventive medicine and community healthcare services, particularly integrating point-of-care (POC) solutions to enhance early disease detection and timely interventions. I am interested in big data and epidemiological research to identify risk factors for chronic diseases and develop effective screening and prevention strategies. By combining critical thinking, data analysis, and evidence synthesis, I aim to advance disease prevention, health promotion, and community-based healthcare. My expertise in research design, biostatistics, and systematic literature review allows me to critically evaluate medical data and translate findings into meaningful clinical applications. Beyond research, I am committed to lifelong learning and interdisciplinary collaboration. My ultimate goal is to become a leading expert in preventive and community medicine, helping to shape healthcare policies and strategies that promote disease prevention and improved quality of life.

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Objavljeno
2025/12/27
Broj časopisa
Ahead of print
Rubrika
Original paper

Sva prava zadržana (c) 2025 Ping-Jen Hu, Yung-Han Lai, Cai-Mei Zheng, Hsin-Ting Lin, Pei-Yu Wang, Chi-Chen Yang, Yu-Ann Fang, Tian-Jong Chang, Chia-Wei Lin, Yuh-Feng Lin, Ming-Yao Chen, Hsiao-Chung Tsai, Huai-Chih Chiang

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