A SHORT LOOK AT MICROBIAL PRODUCERS OF BIOBUTANOL – NEW TRENDS, POTENTIALITIES AND LIMITATIONS
Keywords:
biobutanol; substrates ABE; clostridia, microorganisms
Abstract
Butanol production by microorganisms was first reported by Louis Pasteur in 1861. However, it was not until 60 years later that Chaim Weizmann used anaerobic bacteria of the genera Clostridium for butanol production on a large scale. Interest in acetone-butanol-ethanol fermentation was developed in the 1980s, due to the escalating price of petroleum. Nowadays, the energy crisis, climate change and greenhouse effect have created strong demand for the development of alternative energy sources. Researchers have made an attempt to produce biobutanol from various second-generation feedstocks with new microbial strains and new technologies. The use of numerous waste materials, improved strains and co-cultivation have the potential to improve butanol yield. This paper is dedicated to reviewing recent advances in butanol production by microorganisms.
References
Abdelaal, A.S.,·Jawed, K., Yazdani, S.S., 2019. CRISPR/Cas9‑mediated engineering of Escherichia coli for n‑butanol production from xylose in defined medium. Journal of Industrial Microbiology & Biotechnology 46, 965–975.
Amiri, H., Azarbaijani, R., Parsa Yeganeh, L., Shahzadeh Fazeli, A., Tabatabaei, M., Salekdeh, G.H., Karimi, K., 2016. Nesterenkonia sp. strain F, a halophilic bacterium producing acetone, butanol, and ethanol under aerobic conditions. Scientific Reports 6, 18408.
Amoozegar, M.A., Safarpour, A., Noghabi, K.A., Bakhtiary, T., Ventosa, A., 2019. Halophiles and their vast potential in biofuel production. Frontiers in Microbiology 10, 1895.
Atsumi, S., Cann, A.F., Connor, M.R., Shen, C.R., Smith, K.M., Brynildsen, M.P., Chou K.J., Hanai, T., Liao, J.C., 2008. Metabolic engineering of Escherichia coli for 1-butanol production. Metabolic Engineering 10(6), 305-311.
Berezina, O.V., Brandt, A., Yarotsky, S., Schwarz, W.H., Zverlov, V.V., 2009. Isolation of a new butanol-producing Clostridium strain: high level of hemicellulosic activity and structure of solventogenesis genes of a new Clostridium saccharobutylicum isolate. Systematic and Applied Microbiology 32 (7), 449-459.
Berezina, O.V., Zakharova, N.V., Brandt, A., Yarotsky, S.V., Schwarz, W.H., Zverlov, V.V., 2010. Reconstructing the clostridial n-butanol metabolic pathway in Lactobacillus brevis. Applied Microbiology and Biotechnology, 87 (2), 635-646.
Dellomonaco, C., Clomburg, J.M., Miller, E.N., Gonzalez, R., 2011. Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals. Nature 476 (7360), 355-359.
Dos Santos Vieira, C.F., Maugeri Filho, F., Maciel Filho, R., Pinto Mariano, A., 2019. Acetone-free biobutanol production: Past and recent advances in the Isopropanol-Butanol-Ethanol (IBE) fermentation. Bioresource Technology 287, 121425.
Ferreira, S., Pereira, R., Liu, F., Vilaça, P., Rocha I., 2019. Discovery and implementation of a novel pathway for n-butanol production via 2-oxoglutarate. Biotechnology for Biofuels 12, 230.
Garcia, V.,Pakkila, J., Ojamo, H., Muurinen, E., Keiski, R.L., 2011. Challenges in biobutanol production: how to improve the efficiency? Renewable & Sustainable Energy Reviews 15 (2), 964-980.
Gulevich, A.Y., Skorokhodova, A.Y., Sukhozhenko, A.V., Shakulov, R.S., Debabov, V.G., 2012. Metabolic engineering of Escherichia coli for 1-butanol biosynthesis through the inverted aerobic fatty acid β-oxidation pathway. Biotechnology Letters 34 (3), 463-469.
Guo, J., Ho, J.C.S., Chin, H., Mark, A.E., Zhou, C., Kjelleberg, S., Liedberg, B., Parikh, A.N., Cho. N.J., Hinks, J., Mu, Y., Seviour, T., 2019. Response of microbial membranes to butanol: interdigitation vs. disorder. Physical Chemistry Chemical Physics 21 (22), 11903-11915.
Guo, J., Chia, G.W.N., Berezhnoy, N.V., Cazenave-Gassiot, A., Kjelleberg, S., Hinks, J., Mu, Y., Seviour, T., 2020. Bacterial lipopolysaccharide core structures mediate effects of butanol ingress. Biochimica et Biophysica Acta (BBA) 1862(2):183150.
Halder, P., Azad, K., Shah, S., Sarker, E. 8 - Prospects and technological advancement of cellulosic bioethanol ecofuel production. In: Azad K. (Ed.), Advances in Eco-Fuels for a Sustainable Environment, Woodhead Publishing Series in Energy, 2019, 211-236.
Inui, M., Suda, M., Kimura, S., Yasuda, K., Suzuki, H., Toda, H., Yamamoto, S., Okino, S., Suzuki, N., Yukawa, H., 2008. Expression of Clostridium acetobutylicum butanol synthetic genes in Escherichia coli. Applied Microbiology and Biotechnology 77 (6), 1305-1316.
Jiang, Y., Guo, D., Lu, J., Dürre, P., Dong, W., Yan W, Zhang, W., Ma, J., Jiang, M., Xin, F., 2018. Consolidated bioprocessing of butanol production from xylan by a thermophilic and butanologenic Thermoanaerobacterium sp. M5. Biotechnology for Biofuels 11, 89.
Kolesinska, B., Fraczyk, J., Binczarski, M., Modelska, M., Berlowska, J., Dziugan, P., Antolak, H., Kaminski, Z.J., Witonska, I.A., Kregiel, D., 2019. Butanol synthesis routes for biofuel production: Trends and perspectives. Materials (Basel) 12 (3), pii: E350.
Kuroda, K., Ueda, M., 2016. Cellular and molecular engineering of yeast Saccharomyces cerevisiae for advanced biobutanol production. FEMS Microbiology Letters 363 (3), pii: fnv247.
Lee, S.Y., Park, J.H., Jang, S.H., Nielsen, L.K., Kim, J., Jung, K.S., 2008. Fermentative butanol production by clostridia. Biotechnology and Bioengineering 101 (2), 209-228.
Li, G., Lee, T.H., Liu, Z., Lee, C.F., Zhang C., 2019a. Effects of injection strategies on combustion and emission characteristics of a common-rail diesel engine fueled with isopropanol-butanol-ethanol and diesel blends. Renewable Energy 130, 677-686.
Li, Y., Tang, W., Chen, Y., Liu, J., Lee C.F., 2019b. Potential of acetone-butanol-ethanol (ABE) as a biofuel. Fuel, 242, 673-686.
Lin, Y.L.; Blaschek, H.P., 1983. Butanol production by a butanol-tolerant strain of Clostridium acetobutyricum in extruded corn broth. Applied Environmental Microbiology 45 (3), 966-973.
Liu, X., Gua, Q., Liao, C., Yu, X., 2014. Enhancing butanol tolerance and preventing degeneration in Clostridium acetobutylicum by 1-butanol–glycerol storage during long-term preservation. Biomass and Bioenergy 69,192-197.
Mařík, J. Pexa, M., Kotek, M., Hönig, V., 2014. Comparison of the effect of gasoline – ethanol E85 – butanol on the performance and emission characteristics of the engine Saab 9-5 2.3 l turbo. Agronomy Research 12 (2), 359–366.
Máté de Gérando, H., Wasels, F., Bisson, A., Clement, B., Bidard, F., Jourdier, E., López-Contreras, A.M., Lopes Ferreira, N., 2018. Genome and transcriptome of the natural isopropanol producer Clostridium beijerinckii DSM6423. BMC Genomics 19 (1), 242.
Niglio, S., Marzocchella A., Rehmann, L., 2019. Clostridial conversion of corn syrup to Acetone-Butanol-Ethanol (ABE) via batch and fed-batch fermentation. Heliyon 5 (3), e01401.
Nimbalkar, P.R., Khedkar, M.A., Chavan, P.V., Bankar, S.B., 2018. Biobutanol production using pea pod waste as substrate: Impact of drying on saccharification and fermentation. Renewable Energy 117, 520-529.
Russmayer, H., Marx, H., Sauer, M., 2019. Microbial 2-butanol production with Lactobacillus diolivorans. Biotechnology for Biofuels 12, 262.
Steen, E.J., Chan, R., Prasad, N., Myers, S., Petzold, C.J., Redding, A., Ouellet, M., Keasling, J.D., 2008. Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol. Microbial Cell Factories 7, 36.
Swidah, R., Ogunlabi, O., Grant, C.M., Ashe, M.P., 2018. n-Butanol production in S. cerevisiae: co-ordinate use of endogenous and exogenous pathways. Applied Microbiology and Biotechnology 102 (22), 9857-9866.
Syed,Q.-A., Nadeem, M., Nelofer, R., 2008. Enhanced butanol production by mutant strains of Clostridium acetobutylicum in molasses medium. Turkish Journal of Biochemistry33 (1), 25-30.
Tan, S.Z., Manchester, S., Prather, K.L., 2016. Controlling central carbon metabolism for improved pathway yields in Saccharomyces cerevisiae. ACS Synthetic Biology 5 (2), 116-124.
Xin, F., Chen, T., Jiang, Y., Dong, W., Zhang, W., Zhang, M., Wu, H., Ma, J., Jiang M., 2017. Strategies for improved isopropanol–butanol production by a Clostridium strain from glucose and hemicellulose through consolidated bioprocessing. Biotechnology for Biofuels 10, 118-130.
Xin, F., Yan, W., Zhou, J., Wu, H., Dong, W., Ma, J., Zhang, W., Jiang M., 2018. Exploitation of novel wild type solventogenic strains for butanol production. Biotechnology for Biofuels 11, 252-259.
Zhao, E.M., Zhang, Y., Mehl, J., Park, H., Lalwani, M.A., Toettcher, J.E., Avalos, J.L., 2018. Optogenetic regulation of engineered cellular metabolism for microbial chemical production. Nature 555 (7698), 683-687.
Amiri, H., Azarbaijani, R., Parsa Yeganeh, L., Shahzadeh Fazeli, A., Tabatabaei, M., Salekdeh, G.H., Karimi, K., 2016. Nesterenkonia sp. strain F, a halophilic bacterium producing acetone, butanol, and ethanol under aerobic conditions. Scientific Reports 6, 18408.
Amoozegar, M.A., Safarpour, A., Noghabi, K.A., Bakhtiary, T., Ventosa, A., 2019. Halophiles and their vast potential in biofuel production. Frontiers in Microbiology 10, 1895.
Atsumi, S., Cann, A.F., Connor, M.R., Shen, C.R., Smith, K.M., Brynildsen, M.P., Chou K.J., Hanai, T., Liao, J.C., 2008. Metabolic engineering of Escherichia coli for 1-butanol production. Metabolic Engineering 10(6), 305-311.
Berezina, O.V., Brandt, A., Yarotsky, S., Schwarz, W.H., Zverlov, V.V., 2009. Isolation of a new butanol-producing Clostridium strain: high level of hemicellulosic activity and structure of solventogenesis genes of a new Clostridium saccharobutylicum isolate. Systematic and Applied Microbiology 32 (7), 449-459.
Berezina, O.V., Zakharova, N.V., Brandt, A., Yarotsky, S.V., Schwarz, W.H., Zverlov, V.V., 2010. Reconstructing the clostridial n-butanol metabolic pathway in Lactobacillus brevis. Applied Microbiology and Biotechnology, 87 (2), 635-646.
Dellomonaco, C., Clomburg, J.M., Miller, E.N., Gonzalez, R., 2011. Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals. Nature 476 (7360), 355-359.
Dos Santos Vieira, C.F., Maugeri Filho, F., Maciel Filho, R., Pinto Mariano, A., 2019. Acetone-free biobutanol production: Past and recent advances in the Isopropanol-Butanol-Ethanol (IBE) fermentation. Bioresource Technology 287, 121425.
Ferreira, S., Pereira, R., Liu, F., Vilaça, P., Rocha I., 2019. Discovery and implementation of a novel pathway for n-butanol production via 2-oxoglutarate. Biotechnology for Biofuels 12, 230.
Garcia, V.,Pakkila, J., Ojamo, H., Muurinen, E., Keiski, R.L., 2011. Challenges in biobutanol production: how to improve the efficiency? Renewable & Sustainable Energy Reviews 15 (2), 964-980.
Gulevich, A.Y., Skorokhodova, A.Y., Sukhozhenko, A.V., Shakulov, R.S., Debabov, V.G., 2012. Metabolic engineering of Escherichia coli for 1-butanol biosynthesis through the inverted aerobic fatty acid β-oxidation pathway. Biotechnology Letters 34 (3), 463-469.
Guo, J., Ho, J.C.S., Chin, H., Mark, A.E., Zhou, C., Kjelleberg, S., Liedberg, B., Parikh, A.N., Cho. N.J., Hinks, J., Mu, Y., Seviour, T., 2019. Response of microbial membranes to butanol: interdigitation vs. disorder. Physical Chemistry Chemical Physics 21 (22), 11903-11915.
Guo, J., Chia, G.W.N., Berezhnoy, N.V., Cazenave-Gassiot, A., Kjelleberg, S., Hinks, J., Mu, Y., Seviour, T., 2020. Bacterial lipopolysaccharide core structures mediate effects of butanol ingress. Biochimica et Biophysica Acta (BBA) 1862(2):183150.
Halder, P., Azad, K., Shah, S., Sarker, E. 8 - Prospects and technological advancement of cellulosic bioethanol ecofuel production. In: Azad K. (Ed.), Advances in Eco-Fuels for a Sustainable Environment, Woodhead Publishing Series in Energy, 2019, 211-236.
Inui, M., Suda, M., Kimura, S., Yasuda, K., Suzuki, H., Toda, H., Yamamoto, S., Okino, S., Suzuki, N., Yukawa, H., 2008. Expression of Clostridium acetobutylicum butanol synthetic genes in Escherichia coli. Applied Microbiology and Biotechnology 77 (6), 1305-1316.
Jiang, Y., Guo, D., Lu, J., Dürre, P., Dong, W., Yan W, Zhang, W., Ma, J., Jiang, M., Xin, F., 2018. Consolidated bioprocessing of butanol production from xylan by a thermophilic and butanologenic Thermoanaerobacterium sp. M5. Biotechnology for Biofuels 11, 89.
Kolesinska, B., Fraczyk, J., Binczarski, M., Modelska, M., Berlowska, J., Dziugan, P., Antolak, H., Kaminski, Z.J., Witonska, I.A., Kregiel, D., 2019. Butanol synthesis routes for biofuel production: Trends and perspectives. Materials (Basel) 12 (3), pii: E350.
Kuroda, K., Ueda, M., 2016. Cellular and molecular engineering of yeast Saccharomyces cerevisiae for advanced biobutanol production. FEMS Microbiology Letters 363 (3), pii: fnv247.
Lee, S.Y., Park, J.H., Jang, S.H., Nielsen, L.K., Kim, J., Jung, K.S., 2008. Fermentative butanol production by clostridia. Biotechnology and Bioengineering 101 (2), 209-228.
Li, G., Lee, T.H., Liu, Z., Lee, C.F., Zhang C., 2019a. Effects of injection strategies on combustion and emission characteristics of a common-rail diesel engine fueled with isopropanol-butanol-ethanol and diesel blends. Renewable Energy 130, 677-686.
Li, Y., Tang, W., Chen, Y., Liu, J., Lee C.F., 2019b. Potential of acetone-butanol-ethanol (ABE) as a biofuel. Fuel, 242, 673-686.
Lin, Y.L.; Blaschek, H.P., 1983. Butanol production by a butanol-tolerant strain of Clostridium acetobutyricum in extruded corn broth. Applied Environmental Microbiology 45 (3), 966-973.
Liu, X., Gua, Q., Liao, C., Yu, X., 2014. Enhancing butanol tolerance and preventing degeneration in Clostridium acetobutylicum by 1-butanol–glycerol storage during long-term preservation. Biomass and Bioenergy 69,192-197.
Mařík, J. Pexa, M., Kotek, M., Hönig, V., 2014. Comparison of the effect of gasoline – ethanol E85 – butanol on the performance and emission characteristics of the engine Saab 9-5 2.3 l turbo. Agronomy Research 12 (2), 359–366.
Máté de Gérando, H., Wasels, F., Bisson, A., Clement, B., Bidard, F., Jourdier, E., López-Contreras, A.M., Lopes Ferreira, N., 2018. Genome and transcriptome of the natural isopropanol producer Clostridium beijerinckii DSM6423. BMC Genomics 19 (1), 242.
Niglio, S., Marzocchella A., Rehmann, L., 2019. Clostridial conversion of corn syrup to Acetone-Butanol-Ethanol (ABE) via batch and fed-batch fermentation. Heliyon 5 (3), e01401.
Nimbalkar, P.R., Khedkar, M.A., Chavan, P.V., Bankar, S.B., 2018. Biobutanol production using pea pod waste as substrate: Impact of drying on saccharification and fermentation. Renewable Energy 117, 520-529.
Russmayer, H., Marx, H., Sauer, M., 2019. Microbial 2-butanol production with Lactobacillus diolivorans. Biotechnology for Biofuels 12, 262.
Steen, E.J., Chan, R., Prasad, N., Myers, S., Petzold, C.J., Redding, A., Ouellet, M., Keasling, J.D., 2008. Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol. Microbial Cell Factories 7, 36.
Swidah, R., Ogunlabi, O., Grant, C.M., Ashe, M.P., 2018. n-Butanol production in S. cerevisiae: co-ordinate use of endogenous and exogenous pathways. Applied Microbiology and Biotechnology 102 (22), 9857-9866.
Syed,Q.-A., Nadeem, M., Nelofer, R., 2008. Enhanced butanol production by mutant strains of Clostridium acetobutylicum in molasses medium. Turkish Journal of Biochemistry33 (1), 25-30.
Tan, S.Z., Manchester, S., Prather, K.L., 2016. Controlling central carbon metabolism for improved pathway yields in Saccharomyces cerevisiae. ACS Synthetic Biology 5 (2), 116-124.
Xin, F., Chen, T., Jiang, Y., Dong, W., Zhang, W., Zhang, M., Wu, H., Ma, J., Jiang M., 2017. Strategies for improved isopropanol–butanol production by a Clostridium strain from glucose and hemicellulose through consolidated bioprocessing. Biotechnology for Biofuels 10, 118-130.
Xin, F., Yan, W., Zhou, J., Wu, H., Dong, W., Ma, J., Zhang, W., Jiang M., 2018. Exploitation of novel wild type solventogenic strains for butanol production. Biotechnology for Biofuels 11, 252-259.
Zhao, E.M., Zhang, Y., Mehl, J., Park, H., Lalwani, M.A., Toettcher, J.E., Avalos, J.L., 2018. Optogenetic regulation of engineered cellular metabolism for microbial chemical production. Nature 555 (7698), 683-687.
Published
2021/02/03
Section
Papers