SEVERE AUTONOMIC DYSFUNCTION ASSOCIATED WITH AUTOIMMUNE THYROIDITS IN POST-COVID-19 PATIENT: CASE REPORT AND LITERATURE REVIEW

Gordana Milić; Milica Milošević; Maša Ristić; Nikola Mitović; Ljubica Dimitrijević; Bojana Šalović; Tanja Ješić Petrović

doi:10.5937/medi58-55623

Gordana Milić Department of Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Dr Subotića 13, 11000 Belgrade, Serbia https://orcid.org/0009-0005-6415-8063
Milica Milošević Department of Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Dr Subotića 13, 11000 Belgrade, Serbia https://orcid.org/0009-0004-6138-8819
Maša Ristić Department of Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Dr Subotića 13, 11000 Belgrade, Serbia https://orcid.org/0009-0000-5861-3422
Nikola Mitović Institute of Pathophysiology, University Clinical Centre of Serbia, Dr. Subotica 1, 11000 Belgrade, Serbia https://orcid.org/0000-0002-4642-0110
Ljubica Dimitrijević Department of Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Dr Subotića 13, 11000 Belgrade, Serbia https://orcid.org/0009-0000-5861-3422
Bojana Šalović University of Belgrade, Faculty of Medicine, dr Subotica starijeg 8, 11000 Belgrade, Serbia https://orcid.org/0009-0009-0921-1780
Tanja Ješić Petrović Public Primary Health Care Center Doboj https://orcid.org/0009-0006-2345-4402

DOI: https://doi.org/10.5937/medi58-55623

Ključne reči: COVID-19, Hashimoto’s thyroiditis, autonomic dysfunction

Sažetak

Uvod Cilj našeg rada je prikazati slučaj Hašimotovog tireoiditisa i teške autonomne disfunkcije koji su se razvili tri meseca nakon oporavka od akutne faze COVID-19 infekcije kod 59-godišnje pacijentkinje bez prethodne istorije bolesti štitaste žlezde i autonomnih poremećaja.

Prikaz slučaja Klinička evaluacija pokazala je normalnu funkciju štitaste žlezde uprkos dijagnozi Hašimotovog tireoiditisa, uz izraženu autonomnu disfunkciju (smanjena varijabilnost srčanog ritma i povišen HV). Diskutovani su klinički tok, dijagnostički pristup i strategije lečenja, kao i praćenje pacijentkinje.

Zaključak Povezanost između COVID-19 infekcije i razvoja ovih stanja ukazuje na potrebu za daljim istraživanjem potencijalnog uticaja COVID-19 na imuni sistem, štitastu žlezdu i autonomni nervni sistem.