SEVERE AUTONOMIC DYSFUNCTION ASSOCIATED WITH AUTOIMMUNE THYROIDITS IN POST-COVID-19 PATIENT: CASE REPORT AND LITERATURE REVIEW

Gordana Milic; Milica Milosevic; Masa Ristic; Nikola Mitovic; Ljubica Dimitrijevic; Bojana Salovic; Tanja Jesic Petrovic

doi:10.5937/medi58-55623

Gordana Milic Department of Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Dr Subotića 13, 11000 Belgrade, Serbia https://orcid.org/0009-0005-6415-8063
Milica Milosevic Department of Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Dr Subotića 13, 11000 Belgrade, Serbia https://orcid.org/0009-0004-6138-8819
Masa Ristic Department of Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Dr Subotića 13, 11000 Belgrade, Serbia https://orcid.org/0009-0000-5861-3422
Nikola Mitovic Institute of Pathophysiology, University Clinical Centre of Serbia, Dr. Subotica 1, 11000 Belgrade, Serbia https://orcid.org/0000-0002-4642-0110
Ljubica Dimitrijevic Department of Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Dr Subotića 13, 11000 Belgrade, Serbia https://orcid.org/0009-0000-5861-3422
Bojana Salovic University of Belgrade, Faculty of Medicine, dr Subotica starijeg 8, 11000 Belgrade, Serbia https://orcid.org/0009-0009-0921-1780
Tanja Jesic Petrovic Public Primary Health Care Center Doboj https://orcid.org/0009-0006-2345-4402

DOI: https://doi.org/10.5937/medi58-55623

Abstract

Introduction We present a case of Hashimoto’s thyroiditis and severe autonomic dysfunction three months after the resolution of the acute phase of COVID-19 infection in a patient with no prior thyroid disease and autonomic dysfunction.

Patient Review We discuss clinical presentation, diagnostic evaluation, and subsequent management and follow-up in our patient. Patient tested positive for COVID-19 infection to diagnosis. A 59-year-old female developed Hashimoto’s thyroiditis with normal thyroid function and severe autonomic dysfunction (HRV depressed, HV high ).

Conclusion The temporal relationship between COVID-19 infection in patient described here raises the question of the possible effects of COVID-19 on the immune system the thyroid gland and the autonomic nervous system.

Teška autonomna disfunkcija povezana sa autoimunim tireoiditisom kod post-COVID-19 pacijenta: prikaz slučaja i pregled literature

Abstract