Multidisciplinary approach to management of hipofibrinogenaemia in pregnancy, a case report

  • Slagjana Simeonova Krstevska Univerzitetska ginekolosko akuserska klinika Skopje, oddelenje za peripartalnu intenivnu negu
  • Elizabeta Todorovska Republic institute for transfusion medicine
  • Tatjana Makarovska Bojadzieva
  • Elena Petkovic
  • Saso Stojcevski
  • Igor Samardziski
  • Saso Spasovski
  • Violeta Dejanova
  • Radica Grubovic
  • Florije Raka
  • Viktorija Jovanovska
  • Irena Todorovska
  • Vesna Livrinova
  • Aneta Sima
  • Sasa Jovcevski
  • Daniel Milkovski

Sažetak


Inherited fibrinogen disorders introduce risk for recurrent abortions, sub-chorionic haematoma, placental abruption and postpartum haemorrhage. This is a case report of a successful pregnancy outcome in a 37-year old woman with hypofibrinogenaemia. She was referred to a coagulation test in the first trimester because of history of preeclampsia and HELLP syndrome in previous pregnancy. Hypofibrinogenaemia was diagnosed with fibrinogen level of 0.7 g/L. During the pregnancy she was regularly monitored for fibrinogen levels and multiple cryoprecipitate concentrates were given. She delivered at 39th gestation week, with elective caesarean section under general anaesthesia. There was one episode of postpartum haemorrhage treated with 2 units of red blood cells, repeated infusions of cryoprecipitate to obtain the level of fibrinogen of 2 g/L. She was discharged on the 6th postpartum day in a good condition. In these disorders levels of fibrinogen should be higher than 1 g/L during pregnancy or 2 g/L in case of caesarean section for successful prenatal and peripartal management.

Biografije autora

Slagjana Simeonova Krstevska, Univerzitetska ginekolosko akuserska klinika Skopje, oddelenje za peripartalnu intenivnu negu
Specijalista ginekologije i akuserstva, docent na katedru ginekologije i akuserstva, Medicinski fakultet, Skopje
Elizabeta Todorovska, Republic institute for transfusion medicine

spec transfuzione medicine, PhD

Tatjana Makarovska Bojadzieva

prof dr, spec transfuzione medicine, PhD

Elena Petkovic

specijalista transfuzione medicine, dr medicinskih nauka, asistent

Saso Stojcevski

spec ginekologije i akuserstva, subspecijalista uroginekologije, dr medicinskih nauka, docent

Igor Samardziski

spec ginekologije i akuserstva, perinatolog, dr medicinskih nauka, docent

Saso Spasovski

spec anesteziologije

Violeta Dejanova

specijalista transfuzione medicine, dr med nauka

Radica Grubovic

spec transfuziologije, dr med nauka

Florije Raka

specialist transfuzione medicine

Viktorija Jovanovska

spec ginekologije, dr med nauka, docent

Irena Todorovska

spec ginekologije i akuserstva, subspecijalista perinatologije, asistent

Vesna Livrinova

spec ginekologije, perinatolog, dr med nauka, docent

Aneta Sima

spec ginekologije, docent

Sasa Jovcevski

spec ginekologije i akuserstva

Daniel Milkovski

spec ginekologije i akuserstva, asistent

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2020/06/30
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